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Drug: Estradiol

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Total 7339 results found since Jan 2013.

High levels of physical activity in female adolescents with anorexia nervosa: medical and psychopathological correlates
CONCLUSIONS: Results suggest that high levels of physical activity in acute AN associate with worst clinical conditions at admission, especially in terms of endocrinological and medical features.LEVEL OF EVIDENCE: Level III.PMID:33704692 | DOI:10.1007/s40519-021-01126-3
Source: Eating and weight disorders : EWD - March 11, 2021 Category: Eating Disorders & Weight Management Authors: Anna Riva Mariella Falbo Paolo Passoni Serena Polizzi Alessandro Cattoni Renata Nacinovich Source Type: research

Estradiol activates ERK phosphorylation by binding to ER β to inhibit proliferation and promote apoptosis of human chondrocytes
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Mar 25;41(3):336-343. doi: 10.12122/j.issn.1673-4254.2021.03.04.ABSTRACTOBJECTIVE: To explore the effect of estradiol (E2) binding to its receptor ERβ on the proliferation and apoptosis of C28I2 cells.OBJECTIVE: We cloned the sequence of ESR2 into a recombinant adenovirus plasmid (pAd-ESR2) and packaged the plasmid in HEK293 cells. Normal human chondrocyte C28I2 cells were transfected with Ad-ESR2 or small interfering RNA targeting ESR2-siRNA (ESR2-siRNA), and the effects of treatment with DMSO or E2 on the expression of the proteins associated with endoplasmic reticulum (ER) stress and...
Source: Journal of Southern Medical University - April 14, 2021 Category: Universities & Medical Training Authors: M Zhang Y Yang M Liu L Liang R Luo D Yin F Guo Source Type: research

Estradiol inhibits differentiation of mouse macrophage into a pro-inflammatory phenotype by upregulating the IRE1 < em > α < /em > -XBP1 signaling axis
CONCLUSION: Estrogen can inhibit the differentiation of murine macrophages into a pro-inflammatory phenotype by up-regulating the IRE1α-XBP-1 signaling axis, thereby producing an inhibitory effect on inflammatory response.PMID:35426809 | PMC:PMC9010986 | DOI:10.12122/j.issn.1673-4254.2022.03.17
Source: Journal of Southern Medical University - April 15, 2022 Category: Universities & Medical Training Authors: L Zhuo S Wang X Liu B Chen X Li Source Type: research