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Heterozygous CARD9 mutation favors the development of allergic bronchopulmonary aspergillosis
CONCLUSION: Our study provides the genetic evidence showing that the heterozygous mutation of CARD9S12N, followed by allele expression imbalance of CARD9S12N, facilitates the development of ABPA.PMID:37461235 | DOI:10.1097/CM9.0000000000002786
Source: Chinese Medical Journal - July 18, 2023 Category: General Medicine Authors: Xia Xu Haiwen Lu Jianxiong Li Jielin Duan Zhongwei Wang Jiawei Yang Shuyi Gu Rongguang Luo Shuo Liang Wei Tang Fengying Zhang Jingqing Hang Juan Ge Xin Lin Jieming Qu Xinming Jia Jinfu Xu Source Type: research

Factors associated with parental burden among parents of children with food allergies in China: a cross-sectional study
Conclusions Health professionals should pay more attention to parents who are not at work and whose children have more highly suspected food allergens and more FA-affected systems because these parents often have a higher parental burden. Furthermore, it is important to improve financial support for children’s FA and social support for parents of children with FA to decrease their parental burden.
Source: BMJ Open - September 23, 2022 Category: General Medicine Authors: Li, Z., Tian, L., Liu, H., Tang, S., Chen, Q. Tags: Open access, Public health Source Type: research

Vitamin D supplementation in pregnant women or infants for preventing allergic diseases: a systematic review and meta-analysis of randomized controlled trials
CONCLUSIONS: Supplementation of vitamin D in pregnant women or infants does not have an effect on the primary prevention of allergic diseases.SYSTEMATIC REVIEW REGISTRATION: PROSPERO (CRD42020167747).PMID:35108226 | DOI:10.1097/CM9.0000000000001951
Source: Chinese Medical Journal - February 2, 2022 Category: General Medicine Authors: Chao Luo Yaning Sun Zuojing Zeng Ying Liu Shunlin Peng Source Type: research

Climate change, air pollution, and allergic respiratory diseases: a call to action for health professionals.
Abstract Rising emissions of greenhouse gases in the atmosphere have warmed the planet substantially and are also accompanied by poor air quality. The increased prevalence of allergic airway disease worldwide can be partially attributed to those global environmental changes. Climate change and air pollution pose adverse impacts on respiratory allergies, and that the mechanisms are complex and interactive. Adverse weather conditions, such as extreme temperatures, can act directly on the respiratory tract to induce allergic respiratory illnesses. Thunderstorms and floods can alter the production and distribution of ...
Source: Chinese Medical Journal - June 23, 2020 Category: General Medicine Authors: Deng SZ, Jalaludin BB, Antó JM, Hess JJ, Huang CR Tags: Chin Med J (Engl) Source Type: research

Association between allergic diseases, allergic sensitization and attention-deficit/hyperactivity disorder in children: A large-scale, population-based study
Conclusion Our results suggest that AD and asthma with allergic sensitization are associated with ADHD in children. As allergic sensitization is an increased factor of developing allergic diseases, early control of environmental and allergens exposure could help to modify the burden of ADHD.
Source: Journal of the Chinese Medical Association - November 25, 2017 Category: General Medicine Source Type: research