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Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
Conclusion Bioinformatics and data science training programs in developing countries necessitate incremental and collaborative strategies for their feasible and sustainable development. The progress described here covered decades of collaborative efforts centered on training and research on computationally intensive topics. These efforts laid the groundwork and platforms conducive for hosting a bioinformatics and data science training program in Mali. Training programs are perhaps best facilitated through Africa’s university systems as they are perhaps best positioned to maintain core resources during lapses in sho...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

Anthropometric measures are simple and accurate paediatric weight-prediction proxies in resource-poor settings with a high HIV prevalence
Conclusion The development of nomograms using these equations is warranted to allow for rapid and accurate weight prediction from these simple anthropometric measures in HIV-endemic, resource-constrained settings.
Source: Archives of Disease in Childhood - December 13, 2016 Category: Pediatrics Authors: Whitfield, K. C., Wozniak, R., Pradinuk, M., Karakochuk, C. D., Anabwani, G., Daly, Z., MacLeod, S. M., Larson, C. P., Green, T. J. Tags: Immunology (including allergy), HIV/AIDS, Child health, Sexual health Original article Source Type: research

Partner-based adherence intervention for second-line antiretroviral therapy (ACTG A5234): a multinational randomised trial
Publication date: Available online 11 December 2014 Source:The Lancet HIV Author(s): Robert Gross , Lu Zheng , Alberto La Rosa , Xin Sun , Susan L Rosenkranz , Sandra Wagner Cardoso , Francis Ssali , Rob Camp , Catherine Godfrey , Susan E Cohn , Gregory K Robbins , Anthony Chisada , Carole L Wallis , Nancy R Reynolds , Darlene Lu , Steven A Safren , Lara Hosey , Patrice Severe , Ann C Collier Background Adherence is key to the success of antiretroviral therapy. Enhanced partner support might benefit patients with previous treatment failure. We aimed to assess whether an enhanced partner-based support intervention with mo...
Source: The Lancet HIV - December 11, 2014 Category: Infectious Diseases Source Type: research

UCLA study: To stop spread of HIV, African governments should target hot zones
David Gerberry Efficiency of reducing transmission of HIV in South African provinces, from red (best) to orange (moderate) to green (worst). Blue and pink bars show prevalence of HIV for men and women, respectively. While Ebola has attracted much of the world’s attention recently, a severe HIV epidemic rages on around the world and in sub-Saharan Africa in particular. Globally, more than 34 million people are infected with HIV; in sub-Saharan Africa alone, 3 million new infections occur annually. In an attempt to stop the spread of HIV, governments in the region are considering providing antiretroviral drugs to people w...
Source: UCLA Newsroom: Health Sciences - December 2, 2014 Category: Universities & Medical Training Source Type: news

Isoniazid prophylaxis started at 3-4 months of life does not prevent tuberculosis disease or infection in both HIV-infected and uninfected children
Setting: South Africa and Botswana Patients: The study looked at infants who were born to HIV-infected women. To be included in the study, the infants had to be between 91 and 120 days of life, not infected with or exposed to a case of tuberculosis, without other chronic illness, or immunosuppressed from an infection other than HIV. A total of 1351 children were included in the analysis and were split into two groups based on their HIV status after testing: HIV positive and HIV negative (table 1). Intervention: The infants in both groups were randomly assigned to receive either isoniazid at a daily dose of 10–20...
Source: Archives of Disease in Childhood - Education and Practice - January 16, 2013 Category: Pediatrics Authors: Iro, M. A., Brown, N. Tags: Epidemiologic studies, Immunology (including allergy), Drugs: infectious diseases, HIV/AIDS, Child health, Infant health, Sexual health Structured abstracts of sentinel articles: Picket Source Type: research