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Condition: Dystonia
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Total 70 results found since Jan 2013.

The BioFIND Study (Fox Investigation For New Discovery Of Biomarkers In Parkinson's Disease): Design And Methodology (P4.043)
CONCLUSIONS:The BioFIND study will provide a valuable biospecimen resource for the discovery and validation of novel biomarkers in typical, moderate to advanced PD. Promising markers can then be verified in longitudinal cohorts and more heterogeneous PD subjects.Study Supported by:This study is sponsored by MJFF with support from NINDS. We also thank supports from NIH CTSA (RNA).Disclosure: Dr. Kang has received personal compensation for activities with Caremark Inc. as a medical advisory board member. Dr. Kang has received research support from Allergan, Inc. Dr. Alcalay has received personal compensation for activities w...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Kang, U., Alcalay, R., Goldman, J., Henchcliffe, C., Hogarth, P., Tuite, P., Xie, T., Frasier, M., Kopil, C., Vincent, L., Willis, N., Casaceli, C., Rudolph, A. Tags: Movement Disorders: Parkinson ' s Disease Biomarkers Source Type: research

Response to IncobotulinumtoxinA After Resistance to OnabotulinumtoxinA and RimabotulinumtoxinB (P7.061)
CONCLUSIONS:Switching to incobotulinumtoxinA after secondary resistance to onabotulinumtoxinA and rimabotulinumtoxinB may be a viable treatment option in dystonia.Study Supported by:National Institutes of Health- National Institutes of Neurological Diseases and Stroke and the Dystonia Medical Research FoundationDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Karp has nothing to disclose. Dr. Lungu has nothing to disclose. Dr. Alter has nothing to disclose. Dr. Hallett has received personal compe...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Karp, B., Lungu, C., Alter, K., Hallett, M. Tags: Movement Disorders: Dystonia Treatment Source Type: research

Three Sib-Pairs of Autopsy-Confirmed Progressive Supranuclear Palsy (P5.248)
CONCLUSIONS:Affected members from all three families presented classical clinical and pathological PSP features. However, the age at onset in a sib-pair carrying a MAPT mutation was younger than typical. Future studies are warranted on our MAPT mutation negative families with the goal of identifying a novel gene for PSP associated with late-onset and typical tau pathology.Study Supported By: P50NS72187; the Family of Carl Edward Bolch, Jr. and Susan Bass Bolch; the Society for PSP and the Mayo Foundation for Research and Education and the Max Kade Foundation.Disclosure: Dr. Fujioka has nothing to disclose. Dr. Sanchez Cont...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Fujioka, S., Sanchez Contreras, M., Strongosky, A., Ogaki, K., Whaley, N., Tacik, P., Van Gerpen, J., Uitti, R., Ross, O., Wszolek, Z., Rademakers, R., Dickson, D. Tags: Movement Disorders: Atypical Parkinsonism Source Type: research

Spinning Out of Control: The Black Box of Basilar and Hemiplegic Migraine (P7.176)
CONCLUSIONS:In this retrospective study, triptans were used effectively with no subsequent vascular events for the abortive treatment of migraines with basilar and hemiplegic features. This data also suggests that beta blockers, tricyclic anti-depressants, anti-convulsants, and Botox injections have some efficacy in the treatment of migraines with basilar type and hemiplegic features.Disclosure: Dr. Krel has nothing to disclose. Dr. Mathew has nothing to disclose. Dr. Spinner has received personal compensation for activities with Merz Pharma and Allergan Inc. as speaker bureau member. Dr. Joshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Krel, R., Mathew, P., Spinner, W., Joshi, S. Tags: Headache: Treatment Source Type: research

High Accordance Rate of Neurologist Referrals for Psychogenic Patients with Expert Opinion at the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke (S49.006)
CONCLUSIONS:Neurologist referrals to the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke of psychogenic patients have a high accordance rate (94%) with expert opinion from our Institution.Study Supported by:NIH-NINDSDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Villegas has nothing to disclose. Dr. Esquenazi has nothing to disclose. Dr. Hallett has received personal compensation for activities with Neurotoxin I...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Villegas, M. A. F., Esquenazi, A., Hallett, M. Tags: Practice, Policy, and Ethics Source Type: research

Diagnosis and Treatment of Abductor Hallucis Focal Dystonia With Botulinum Toxin Injection: A Case Presentation
Orthopedic foot deformities can result from neurologic conditions such as stroke, multiple sclerosis, and cerebral palsy . In such cases, imaging studies of the foot are often not diagnostic of the underlying problem. Although it is not always considered, electrodiagnostic assessment can detect dystonia, spasticity, and neuropathy . The information gained from these electrodiagnostic studies can guide therapy, including medical and surgical management. This case study describes the successful evaluation and treatment of abducted hallux deformity by using electrodiagnostic testing and botulinum injection treatment.
Source: PM and R - August 1, 2013 Category: Rehabilitation Authors: Nathan S. Rosenberg, Ib R. Odderson Tags: Case Presentation Source Type: research

S1-4. The effect of repetitive Transcranial Magnetic Stimulation (rTMS) in patients with intractable cervical dystonia and/or post-stroke central pain
In conclusion, rTMS is useful as one of the option in the treatment of intractable CD and CPSP.
Source: Clinical Neurophysiology - July 16, 2013 Category: Neuroscience Authors: Norihiro Muraoka, Minoru Shigemori, Fumihiko Koike, Masao Hiromatu, Keiko Suematu, Motohiro Morioka Tags: Society Proceedings Source Type: research

Systematic Literature Review of AbobotulinumtoxinA in Clinical Trials for Therapeutic Uses (P02.069)
CONCLUSIONS: Based on data extracted from 20 randomized clinical studies, a strong evidence base exists for the use of ABO in limb spasticity. Based on data from 8 studies, ABO appears efficacious for blepharospasm, hemifacial spasm, sialorrhea, truncal dystonia, and writers cramp.Supported by: Ipsen.Disclosure: Dr. Chen has received personal compensation for activities with Teva Neuroscience. Dr. Dashtipour has received personal compensation for activities with Teva Neuroscience, Allergan, Inc., Ipsen, Merz Pharma, Solstice and Lundbeck. Dr. Chen has received personal compensation for activities with Teva Neuroscience.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Chen, J., Dashtipour, K., Braun, L. Tags: P02 Movement Disorders: Dystonia Source Type: research

Adverse Events with Implantable Deep Brain Stimulators - Trends and Insight from the FDA MAUDE Database, 2001 - 2007 (P02.074)
CONCLUSIONS: The frequency of AEs with DBS devices increased dramatically between 2001 and 2007. Within the accepted limitations of a voluntary database, infection and device malfunction are common AEs and often lead to explantation. More serious events such as death or stroke are uncommon. This study includes larger numbers of AEs than prior published reports and reinforces the need for device registries for long-term safety evaluation.Disclosure: Dr. Diaz has nothing to disclose. Dr. McMurtray has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Diaz, N., McMurtray, A. Tags: P02 Movement Disorders: Dystonia Source Type: research