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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Disability
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Total 286 results found since Jan 2013.
Plasma D-dimer Level, the Promising Prognostic Biomarker for the Acute Cerebral Infarction Patients
Despite being an important cause of death and functional disability, acute cerebral infarction (ACI) lacks accurate and easy tools to predict the outcome of patients beyond clinical variables such as age and stroke severity.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2016 Category: Neurology Authors: Jing Wang, Ruizhuo Ning, Yuping Wang Source Type: research
Different Characteristics of Anterior and Posterior Branch Atheromatous Diseases with or without Early Neurologic Deterioration
Among several types of ischemic stroke (IS), branch atheromatous disease (BAD) is known to be the leading cause of disability.
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2017 Category: Neurology Authors: Yoshiaki Takahashi, Toru Yamashita, Ryuta Morihara, Yumiko Nakano, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Yasuhiro Manabe, Koji Abe Source Type: research
Increased Risk for Unfavorable Outcome in Patients with Pre-Existing Disability Undergoing Endovascular Therapy
Most studies evaluating endovascular therapy (EVT) for stroke only included patients without pre-existing disabilities. However, in real life many patients have pre-existing disabilities, and whether they can benefit from EVT remains unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2017 Category: Neurology Authors: Ronen R. Leker, Pavel Gavriliuc, Nour Eddine Yaghmour, John M. Gomori, Jose E. Cohen Source Type: research
Relation among Psychopathological Symptoms, Neuropsychological Domains, and Functional Disability in Subacute Poststroke Rehabilitation
Neuropsychiatric disorders are commonly observed in patients following a stroke. Among 30%-60% of poststroke patients suffer from depression and anxiety (18%-25%). Some authors suggest an association between psychological symptoms and lesions in specific brain areas. In particular, lesions in left frontal cortex and left basal ganglia are frequently associated with poststroke depression and with comorbidity of anxiety and depression, whereas isolated anxiety symptoms are frequently observed after right hemispheric lesions.
Source: Journal of Stroke and Cerebrovascular Diseases - February 5, 2018 Category: Neurology Authors: Viviana Lo Buono, Lilla Bonanno, Rosanna Palmeri, Francesco Corallo, Sergio Parisi, Antonia Trinchera, Edoardo Sessa, Patrizia Pollicino, Bruno Galletti, Placido Bramanti, Silvia Marino Source Type: research
Dexmedetomidine Protects Against Neurological Dysfunction in a Mouse Intracerebral Hemorrhage Model by Inhibiting Mitochondrial Dysfunction-Derived Oxidative Stress
Intracerebral hemorrhage (ICH) is a subtype of stroke with high disability and mortality. Dexmedetomidine (Dex) has been shown to provide neuroprotection in several neurological diseases. The aim of present study was to investigate the effects of Dex on ICH-induced neurological deficits and brain injury and the underlying mechanisms.
Source: Journal of Stroke and Cerebrovascular Diseases - February 20, 2019 Category: Neurology Authors: Jing Huang, Qiang Jiang Source Type: research
Retraction notice to “Beneficial Effect of Etidronate Therapy in Chronically Hospitalized, Disabled Patients with Stroke” Journal of Stroke and Cerebrovascular Diseases, Volume 19, Issue 3, May 2010, Pages 198-203
Available online: 29 April 2010
Source: Journal of Stroke and Cerebrovascular Diseases - July 31, 2019 Category: Neurology Authors: Yoshihiro Sato, Jun Iwamoto, Yoshiaki Honda Tags: Retraction notice Source Type: research
Is There Equipoise Regarding the Optimal Medical Treatment of Patients with Asymptomatic White Matter Hyperintensities?
Background: White matter hyperintensity (WMH) is a common manifestation of chronic ischemic microvascular disease that heralds greater risk of functional disability, stroke, and dementia. SPRINT MIND recently reported that intensive blood pressure reduction resulted in lower rates of mild cognitive impairment and WMH progression, suggesting that medical interventions could have a measurable impact on WMH. We conducted an anonymous survey of providers in the NINDS StrokeNet to better understand neurologist attitudes about asymptomatic WMH.
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2019 Category: Neurology Authors: Adam de Havenon, Shyam Prabhakaran, Tanya Turan, Rebecca Gottesman, Sharon Yeatts, Natalia Rost Source Type: research
A Preliminary Study of Dual-Task Training Using Virtual Reality: Influence on Walking and Balance in Chronic Poststroke Survivors
Stroke is a leading cause of death and disability in the Western world, and leads to impaired balance and mobility. Objective: To investigate the feasibility of using a Virtual Reality-based dual task of an upper extremity while treadmill walking, to improve gait and functional balance performance of chronic poststroke survivors.
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2019 Category: Neurology Authors: Pavel Fishbein, Yeshayahu Hutzler, Motti Ratmansky, Iuly Treger, Ayelet Dunsky Source Type: research
Edaravone Administration Confers Neuroprotection after Experimental Intracerebral Hemorrhage in Rats via NLRP3 Suppression
Intracerebral hemorrhage (ICH) is one of the leading causes of disability and mortality in adult, which lacks effective therapies. Edaravone has showed its neuroprotective effects after ischemia stroke, but its effects and possible mechanisms after ICH are poorly understood. Here, we investigated whether edaravone confers neuroprotection after ICH in rats and explored the potential mechanisms involved.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2019 Category: Neurology Authors: Hongping Miao, Yongxiang Jiang, Junjun Geng, Bo Zhang, Gang Zhu, Jun Tang Source Type: research
White Matter Lesion Severity is Associated with Intraventricular Hemorrhage in Spontaneous Intracerebral Hemorrhage
Background: Intraventricular hemorrhage (IVH) and white matter lesion (WML) severity are associated with higher rates of death and disability in intracerebral hemorrhage (ICH). A prior report identified an increased risk of IVH with greater WML burden but did not control for location of ICH. We sought to determine whether a higher degree of WML is associated with a higher risk of IVH after controlling for ICH location. Methods: Utilizing the patient population from 2 large ICH studies; the Genetic and Environmental Risk Factors for Hemorrhagic Stroke (GERFHS III) Study and the Ethnic/Racial Variations of Intracerebral Hemo...
Source: Journal of Stroke and Cerebrovascular Diseases - February 27, 2020 Category: Neurology Authors: Vaibhav Vagal, Simone U. Venema, Tyler P. Behymer, Eva A. Mistry, Padmini Sekar, Russell P. Sawyer, Lee Gilkerson, Charles J. Moomaw, Mary Haverbusch, Elisheva R. Coleman, Matthew L. Flaherty, Carson Van Sanford, Robert J. Stanton, Christopher Anderson, J Source Type: research
Challenges and Improvements of Developing an Ischemia Mouse Model Through Bilateral Common Carotid Artery Occlusion
Brain ischemia is one of the principal causes of death and disability worldwide in which prevention or an effective treatment does not exist. In order to develop successful treatments, an adequate and useful ischemia model is essential. Transient global cerebral ischemia is one of the most interesting pathological conditions in stroke studies because of the observed degeneration of forebrain and delayed neuronal cell death in selective vulnerable regions such as hippocampus. Transient occlusion of both common carotid arteries is the most convenient model to induce tGCI.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2020 Category: Neurology Authors: Lilia Carolina Le ón-Moreno, Rolando Castañeda-Arellano, Jorge David Rivas-Carrillo, Sergio Horacio Dueñas-Jiménez Tags: Review Article Source Type: research
Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d
In this study, we explored the neuroprotective effects of miR-219a-5p on brain using an in vitro ischemia model (mouse neuroblastoma N2a cells treated with oxyglucose deprivation and reperfusion), and in vivo cerebral I/R model in mice.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2020 Category: Neurology Authors: Min-Yi Lu, Jin-Rong Wu, Rui-Bing Liang, Yu-Peng Wang, You-Cai Zhu, Zi-Ting Ma, Hao Zhang, Jie Zan, Wen Tan Source Type: research
Predicting hemorrhagic transformation in patients not submitted to reperfusion therapies
Well studied in patients with ischemic stroke after reperfusion therapies (RT), hemorrhagic transformation (HT) is also common in patients not treated with RT and can lead to disability even in initially asymptomatic cases. The best predictors of HT in patients not treated with RT are not well established. Therefore, we aimed to identify predictors of HT in patients not submitted to RT and create a user-friendly predictive score (PROpHET).
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Joao Brainer Clares de Andrade, Jay P. Mohr, Fabricio Oliveira Lima, Joao Jos é de Freitas Carvalho, Victor Aguiar Evangelista de Farias, Jamary Oliveira-Filho, Octavio Marques Pontes-Neto, Rodrigo Bazan, Kristel Larisa Back Merida, Luisa Franciscato, Ma Source Type: research
Insulin-Like Growth Factor 2 (IGF-2) Regulates Neuronal Density and IGF-2 Distribution Following Hippocampal Intracerebral Hemorrhage
Memory is the most critical cognitive function in humans. Hippocampus infarcts and artery lesions in stroke and trauma cause levels of memory loss, and it is an apparent cause of disability in the communities.1,2 Intracerebral Hemorrhage (ICH) caused by bleeding in the brain parenchyma and penetration of the hematoma into the hippocampus leads to severe memory damage.3,4 Many arteries supply the hippocampus, most of which branch off of the posterior cerebral artery, the anterior temporal, and the anterior choroidal arteries.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Farzaneh Vafaee, Asadollah Zarifkar, Masoumeh Emamghoreishi, Mohammad Reza Namavar, Shima Shirzad, Hamed Ghazavi, Vahid Mahdavizadeh Source Type: research
