White Matter Lesion Severity is Associated with Intraventricular Hemorrhage in Spontaneous Intracerebral Hemorrhage
Background: Intraventricular hemorrhage (IVH) and white matter lesion (WML) severity are associated with higher rates of death and disability in intracerebral hemorrhage (ICH). A prior report identified an increased risk of IVH with greater WML burden but did not control for location of ICH. We sought to determine whether a higher degree of WML is associated with a higher risk of IVH after controlling for ICH location. Methods: Utilizing the patient population from 2 large ICH studies; the Genetic and Environmental Risk Factors for Hemorrhagic Stroke (GERFHS III) Study and the Ethnic/Racial Variations of Intracerebral Hemorrhage study, we graded WML using the Van Swieten Scale (0-1 for mild, 2 for moderate, and 3-4 for severe WML) and presence or absence of IVH in baseline CT scans.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Vaibhav Vagal, Simone U. Venema, Tyler P. Behymer, Eva A. Mistry, Padmini Sekar, Russell P. Sawyer, Lee Gilkerson, Charles J. Moomaw, Mary Haverbusch, Elisheva R. Coleman, Matthew L. Flaherty, Carson Van Sanford, Robert J. Stanton, Christopher Anderson, J Source Type: research
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