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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African men: The SABPA study
Conclusion: Novel findings of behavioural resilience were apparent in the AC African female despite a high prevalence of risk markers. In AC males, chronic hyperglycaemia facilitated endothelial dysfunction, i.e. a physiological “loss of control” and susceptibility to stroke risk.
Source: International Journal of Cardiology - November 19, 2012 Category: Cardiology Authors: L. Malan, M. Hamer, M.P. Schlaich, G.W. Lambert, T. Ziemssen, M. Reimann, H.S. Steyn, R. Schutte, W. Smith, J.M. van Rooyen, C.M.T. Fourie, N.T. Malan Tags: Original Articles Source Type: research
Left atrial size and function as predictors of new-onset of atrial fibrillation in patients with asymptomatic aortic stenosis: The simvastatin and ezetimibe in aortic stenosis study
Abstract: Background: Left atrial (LA) size and function change with chronically increased left ventricular (LV) filling pressures. It remains unclear whether these variations in LA parameters can predict new-onset atrial fibrillation (AF) in asymptomatic patients with aortic stenosis (AS).Methods: Data were obtained in asymptomatic patients with mild-to-moderate AS (2.5≤ transaortic Doppler velocity ≤4.0m/s), preserved LV ejection fraction (EF), no previous AF, and were enrolled in the Simvastatin and Ezetimibe in Aortic Stenosis study. Peak-aortic velocity, LAmax volume & LAmin volume were measured by echocardiograph...
Source: International Journal of Cardiology - February 18, 2013 Category: Cardiology Authors: Casper N. Bang, Morten Dalsgaard, Anders M. Greve, Lars Køber, Christa Gohlke-Baerwolf, Simon Ray, Anne B. Rossebø, Kenneth Egstrup, Kristian Wachtell Tags: Original Articles Source Type: research
Cholesterol-adjusted vitamin E serum levels are associated with cardiovascular events in patients with non-valvular atrial fibrillation
Abstract: Background: Non-valvular atrial fibrillation is associated with an increase in thromboembolism, i.e. stroke, and atherosclerotic events, i.e. myocardial infarction. Vitamin E possesses anti-coagulant as well as anti-atherosclerotic properties.Our aim was to assess whether vitamin E is associated with cardiovascular events in patients with non-valvular atrial fibrillation.Methods: Serum levels of cholesterol-adjusted vitamin E were measured in 1012 patients with non-valvular atrial fibrillation. Patients were followed for a mean time of 27.0months, and cardiovascular events, such as cardiovascular death and fatal ...
Source: International Journal of Cardiology - May 7, 2013 Category: Cardiology Authors: Roberto Cangemi, Pasquale Pignatelli, Roberto Carnevale, Gino Roberto Corazza, Daniele Pastori, Alessio Farcomeni, Stefania Basili, Giovanni Davì, Domenico Ferro, William R. Hiatt, Giuseppe Licata, Gregory Y.H. Lip, Lorenzo Loffredo, Pier Mannuccio Mannu Tags: Original Articles Source Type: research
There is a need for independent studies about new oral anticoagulants in atrial fibrillation patients
Dabigatran, rivaroxaban, and apixaban are new oral anticoagulants (NOAC) which have been investigated in patients with atrial fibrillation (AF) for primary and secondary prevention of stroke and thromboembolism . In RELY, ROCKET-AF and ARISTOTLE, NOAC had a similar efficacy and safety profile like vitamin-K-antagonists (VKA). Based on these results, NOAC are recommended by national and international societies as an alternative to VKA or even the first choice drug for the prevention of stroke or embolism in AF-patients.
Source: International Journal of Cardiology - January 21, 2014 Category: Cardiology Authors: Claudia Stöllberger, Birke Schneider, Josef Finsterer Tags: Online Letters to the Editor Source Type: research
The CHA2DS2-VASc score predicts 320-slice CT-based coronary artery plaques and >50% stenosis in subjects with chronic and paroxysmal atrial fibrillation
The CHADS2 score is a simple score to evaluate the risk of occurrence of cerebral infarction in subjects with atrial fibrillation (AF) that includes the variables of age (≥75yrs), hypertension, diabetes mellitus, previous stroke, and heart failure. Furthermore the CHA2DS2-VASc score is a more detailed assessment scheme than the CHADS2 score to further stratify the risk of occurrence of cerebral infarction in subjects with AF considering the following factors; female sex, presence of vascular disease, and age (≥65yrs) as stroke risk factors. Since both CHADS2 score and CHA2DS2-VASc score include coronary risk factors, t...
Source: International Journal of Cardiology - January 23, 2014 Category: Cardiology Authors: Nobusada Funabashi, Masae Uehara, Hiroyuki Takaoka, Yoshio Kobayashi Tags: Online Letters to the Editor Source Type: research
The value of CHADS score in predicting new-onset atrial fibrillation in Chinese patients with acute myocardial infarction
Previous studies have shown that new-onset atrial fibrillation (AF) in the setting of acute myocardial infarction (AMI) was associated with increased in-hospital and long term mortality [1,2]. Therefore, it was crucial to recognize the patients with AMI who were on the increased risk for developing new-onset AF. CHADS2 score (congestive heart failure, hypertension, age≥75years, diabetes and previous stroke or transient ischemic attack) was a very useful and convenient scoring system, which was widely used for the stroke risk stratification in the patients with non-valvular AF [3].
Source: International Journal of Cardiology - August 5, 2014 Category: Cardiology Authors: Xiaowei Zhang, Guangping Li, Zhiqiang Zhao, Yanmin Xu, Tong Liu Source Type: research
Red blood cell distribution width and left atrial thrombus or spontaneous echo contrast in patients with non-valvular atrial fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with an increased risk of cardio-embolic stroke and mortality. AF patients are under an increased risk of thromboembolism and stroke primarily from the development of thrombi within the left atrium. Pathological changes in blood constituents like slow blood flow, stasis, form a vortex, promote atrial endothelial damage and left atrial thrombus (LAT) formation [1]. Transesophageal echocardiography (TEE) can help us to identify LAT and left atrial spontaneous echo contrast (LASEC) which has been demonstrated as a precursor of LAT [2].
Source: International Journal of Cardiology - November 25, 2014 Category: Cardiology Authors: Jianping Zhao, Tong Liu, Panagiotis Korantzopoulos, Huaying Fu, Qingmiao Shao, Ya Suo, Chenghuan Zheng, Gang Xu, Enzhao Liu, Yanmin Xu, Changyu Zhou, Guangping Li Tags: Letter to the editor Source Type: research
Antiplatelet Properties of Oral Anticoagulants
Until recently, vitamin K antagonists (VKA) were the only oral anticoagulant drugs used in clinical practice for stroke or systemic embolism prevention in patients with non-valvular atrial fibrillation (AF). New oral anticoagulant drugs such as dabigatran etexilate and rivaroxaban have been developed and are currently available as an alternative in this indication. Both drugs were demonstrated to be non-inferior to warfarin for the prevention of stroke or systemic embolism in patients with non-valvular AF in the RE-LY and ROCKET trials [1,2].
Source: International Journal of Cardiology - December 23, 2014 Category: Cardiology Authors: Corinne Frère, Marc Laine, Franck Paganelli, Françoise Dignat-George, Laurent Bonello Tags: Letter to the Editor Source Type: research
Underuse and Overuse of Anticoagulation for Atrial Fibrillation: A Study in Indigenous and Non-Indigenous Australians
Atrial fibrillation (AF) is a leading cause of preventable stroke in Australia. Given anticoagulation therapy can significantly reduce this stroke risk, we sought to characterise anticoagulation use in Indigenous and non-Indigenous Australians with AF.
Source: International Journal of Cardiology - March 4, 2015 Category: Cardiology Authors: Christopher X. Wong, Sarah W. Lee, Siang Wei Gan, Rajiv Mahajan, Geetanjali Rangnekar, Rajeev K. Pathak, Darragh Twomey, Carlee Schultz, Anand N. Ganesan, Anthony G. Brooks, Kurt C. Roberts-Thomson, Alex Brown, Dennis H. Lau, Prashanthan Sanders Source Type: research
Relation of growth differentiation factor-15 with CHADS-VASc score in Chinese patients with non-valvular atrial fibrillation
Atrial fibrillation (AF) is the most common sustained arrhythmia. AF significantly increases the risk of stroke, systemic thromboembolism and cardiac death. The refined CHA2DS2-VASc score includes additional risk factors and performs better than CHADS2 score in identifying patients who are truly low-risk patients. It is the recommended scheme for stroke risk stratification in patients with non-valvular AF [1]. In a recent substudy of the ARISTOTLE trial, Wallentin et al. [2,3] evaluated the prognostic role of growth differentiation factor-15 (GDF-15), a biomarker of oxidative stress and inflammation, in patients with AF re...
Source: International Journal of Cardiology - March 10, 2015 Category: Cardiology Authors: Tong Liu, Qingmiao Shao, Chee Yuan Ng, Jianping Zhao, Gang Xu, Yanmin Xu, Guangping Li Tags: Letter to the Editor Source Type: research
Health status, geriatric syndromes and prescription of oral anticoagulant therapy in elderly medical in-patients with atrial fibrillation: A prospective observational study
Although oral anticoagulants (OAs) proved to be effective for prevention of stroke in elderly with atrial fibrillation (AF) [1–3], this therapy is widely underused particularly in the oldest patients who, in reason of their high risk of stroke, should derive the greatest benefit from anticoagulant therapy [4–7]. We hypothesized that poor health conditions and presence of common geriatric syndromes might influence physicians’ attitude to prescribe OAs. We investigated prevalence of common geriatric syndromes and contraindications to OAs in real-world older medical in-patients with AF, and whether these variables are a...
Source: International Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: M. Bo, F. Li Puma, M. Badinella Martini, Y. Falcone, M. Iacovino, E. Grisoglio, M. Bonetto, G. Isaia, G. Ciccone, G.C. Isaia, F. Gaita Source Type: research
Reply: Health status, geriatric syndromes and prescription of oral anticoagulant therapy in elderly medical in-patients with atrial fibrillation: A prospective observational study
We agree with the content of the letter from Dr Jolobe OMP and, specifically we concur with his conclusion, where he underlines the fragile evidence for aspirin use in the prevention of atrial fibrillation (AF)-related stroke. According to recent European guidelines [1], our study aimed to assess prevalence of and variables associated with under-prescription of currently recommended anticoagulant therapy for AF patients, including vitamin K antagonists (VKAs) and new direct oral anticoagulants (DOAs), but not those associated with use or under-use of aspirin, which is currently not recommended for prevention of AF-related stroke.
Source: International Journal of Cardiology - April 15, 2015 Category: Cardiology Authors: M. Bo, F. Li Puma, M. Badinella Martini, Y. Falcone, M. Iacovino, E. Grisoglio, M. Bonetto, G. Isaia, G. Ciccone, G.C. Isaia, F. Gaita Tags: Letters to the Editor Source Type: research
Long sheath filling defect during left atrial apppendage occlusion device placement
We report a rare case in which there was periprocedural thrombus formation in sheath and left atrium and its successful recognition and uneventful retrieval during LAA occlusion.
Source: International Journal of Cardiology - July 2, 2015 Category: Cardiology Authors: Rohit Walia, Li-Wei Lo, Yat-Yin Lam, Wen-Chung Yu, Shih-Ann Chen Source Type: research
Long sheath filling defect during left atrial appendage occlusion device placement
We report a rare case in which there was periprocedural thrombus formation in sheath and left atrium and its successful recognition and uneventful retrieval during LAA occlusion.
Source: International Journal of Cardiology - July 2, 2015 Category: Cardiology Authors: Rohit Walia, Li-Wei Lo, Yat-Yin Lam, Wen-Chung Yu, Shih-Ann Chen Tags: Letter to the Editor Source Type: research
