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A Real-World Evaluation of Primary Medication Nonadherence in Patients with Nonvalvular Atrial Fibrillation Prescribed Oral Anticoagulants in the United States
ConclusionsMore than one-quarter of patients experienced PMN within 30 days of their initial prescription order. This rate decreased over a longer period, suggesting a delay in fills. Understanding the factors associated with PMN is warranted to develop effective interventions for improving OAC treatment rates in NVAF.
Source: American Journal of Cardiovascular Drugs - June 10, 2023 Category: Cardiology Source Type: research

Comparative Effectiveness and Safety of Rivaroxaban and Warfarin Among Nonvalvular Atrial Fibrillation (NVAF) Patients with Obesity and Polypharmacy in the United States (US)
ConclusionsThese results suggest that rivaroxaban is an effective and safe treatment option among NVAF patients with obesity and polypharmacy in a commercially-insured US population.
Source: Advances in Therapy - May 25, 2021 Category: Drugs & Pharmacology Source Type: research

Prevalence of atrial fibrillation in hospital encounters with end-stage chronic obstructive pulmonary disease on home oxygen: National trends in the United States.
CONCLUSION: AF prevalence in hospital encounters with end-stage COPD increased from 2003 to 2014. Better management strategies for end-stage COPD patients comorbid with AF are needed, especially in elderly individuals. PMID: 30684473 [PubMed - as supplied by publisher]
Source: Chest - January 23, 2019 Category: Respiratory Medicine Authors: Xiao X, Han H, Wu C, He Q, Ruan Y, Zhai Y, Gao Y, Zhao X, He J Tags: Chest Source Type: research

Stroke prevention strategies in North American patients with atrial fibrillation: the GLORIA ‐AF registry program
ConclusionsIn GLORIA‐AF, 20% of the population comprising males with CHA2DS2‐VASc ≥1 and females with CHA2DS2‐VASc ≥2 did not receive oral anticoagulation therapy. Patient characteristics associated with a lower likelihood of OAC prescription were use of antiplatelet drugs, paroxysmal pattern of AF, a history of falls, and prior bleeding.
Source: Clinical Cardiology - February 1, 2018 Category: Cardiology Authors: William F. McIntyre, David Conen, Brian Olshansky, Jonathan L. Halperin, Emil Hayek, Menno V. Huisman, Gregory Y.H. Lip, Shihai Lu, Jeff S. Healey Tags: CLINICAL INVESTIGATIONS Source Type: research