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Condition: Ataxia

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Total 492 results found since Jan 2013.

Recurrent Strokes in Giant Cell Arteritis: Treatment Dilemma (P4.374)
Conclusions: Steroid resistant, aggressive GCA cases can lead to severe extracranial vasculopathy, dissection, recurrent strokes, and death. Thus we suggest that aggressive immunosuppression be considered early, particularly if complicated with arterial dissection and stroke. These patients may benefit from other potent immunosuppressant drugs such as disease modifying anti-rheumatic drugs, acyclovir, or monoclonal antibodies.Disclosure: Dr. Yadala has nothing to disclose. Dr. Kaur has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Lleva has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yadala, V., Kaur, P., Sahni, R., Lleva, P. E. Tags: Cerebrovascular Case Reports Source Type: research

A Novel Variant in Non-coding Region of GJB1 Is Associated With X-Linked Charcot-Marie-Tooth Disease Type 1 and Transient CNS Symptoms
Conclusion A novel GJB1 variant of c.-170T>G in non-coding region was found in this big Chinese CMTX1 pedigree. This is the first report of variant in non-coding DNA sequence associated with transient CNS symptoms. Thyroid malfunction may contribute to the CNS symptoms in this case. Ethics Statement This study has been reviewed and approved by the Ethics Committee of the China-Japan Union Hospital of Jilin University. Each member of the family provided written informed consent to the participation in the study, the genetic test, and authorized to publish the study including the photos in accordance with the Decl...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Paradoxical Embolism in a Case of Hereditary Hemorrhagic Telangiectasia: Case Report with Literature Review
We describe a 48-year-old male who presented with acute onset giddiness, mild dysarthria, right hemiparesis, and ataxia. Clinical examinations indicated left cerebellar signs with right hemiparesis. Additionally, the patient had significant clubbing and mild cyanosis. A strong family history of epistaxis and hemoptysis was noted. His Magnetic resonance imaging of the brain showed acute left cerebellar and left frontal cortical infarct with normal vessels. The routine stroke and cardiac workup were normal. Chest X-ray showed bilateral lower zone opacities. Contrast-enhanced computerized tomogram (CT) of the chest showed bil...
Source: Neurology India - July 5, 2020 Category: Neurology Authors: Neena Baby Sabu George Kunnathuparambil Prasanth Varghese Aneesh Mangalasseril Kuriakose Source Type: research

Itemized NIHSS subsets predict positive MRI strokes in patients with mild deficits (P5.138)
Conclusion: NIHSS score subsets predict DWI positivity in mild strokes. The presence of neglect or visual field deficits on the NIHSS subsets is most likely to have an MRI correlate even in patients with low NIHSS.Disclosure: Dr. Yaghi has nothing to disclose. Dr. Herber has nothing to disclose. Dr. Willey has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Andrews has nothing to disclose. Dr. Marshall has nothing to disclose. Dr. Lazar has received personal compensation for activities with Claret Medical, Inc. as a clinical steering committee participant. Dr. Boden-Albala has received personal compensation fo...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Yaghi, S., Herber, C., Willey, J., Boehme, A., Andrews, H., Marshall, R., Lazar, R., Boden-Albala, B. Tags: Cerebrovascular Disease and Interventional Neurology: Clinical Research Tools, Methods, and Innovations Source Type: research

Can emergency physicians accurately rule out a central cause of vertigo using the HINTS exam? A systematic review and meta-analysis.
CONCLUSIONS: The HINTS exam when used in isolation by emergency physicians has not been shown to be sufficiently accurate to rule out a stroke in those presenting with AVS. PMID: 32167642 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - March 12, 2020 Category: Emergency Medicine Authors: Ohle R, Montpellier RA, Marchadier V, Wharton A, McIsaac S, Anderson M, Savage D Tags: Acad Emerg Med Source Type: research

O-040 Initial clinical experience with the bendit steerable articulating tip microcatheter for intracranial access and intervention
ConclusionsInitial clinical experience with the controlled articulation that permits flexion at the tip of the microcatheter demonstrated it to be safe. Access to difficult proximal origin curves, and distal clinoidal/ophthalmic segment anatomy may be improved due to the high torque transmission, and acute angulation of this microcatheter. Further experience with the delivery of therapeutic devices will be necessary to better understand the potential role that the present catheter may play in modern neurointerventional procedures.Abstract O-040 Table 1 Patient/Indication/Comorbidities/Treatment/Bendit 21 Role 60s F Cerebr...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Qiao, Y., Zhang, Y., Tsappidi, S., Mehta, T., Hui, F. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

A Case of Resolution of Thalamic Pain Syndrome Following Endovascular Stenting (P4.352)
Conclusions: CPSP may be in part due to chronic hypoperfusion. Endovascular stenting may have led to the resolution of the patient’s CPSP.Disclosure: Dr. Le has nothing to disclose. Dr. Rasmussen has nothing to disclose. Dr. Noonan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Le, S., Rasmussen, J., Noonan, P. Tags: Cerebrovascular Case Reports Source Type: research

Proximal Occlusion Scale for Rapid Triage of Potential Endovascular Therapy Candidates (S47.002)
Conclusions: We report a proximal occlusion score to rapidly identify and triage patients most likely to benefit from urgent evaluation for endovascular therapy. Using multivariate analysis selected features of the presenting neurological exam were predictive of proximal arterial occlusion significantly better that that achieved by an NIHSS cutoff. The proximal occlusion scale could be performed faster than the NIHSS. Utilization of this tool in community hospitals without direct neurologist support may aid in the triage of stroke patients in need of endovascular therapy. Further evaluation in larger cohorts is required.Di...
Source: Neurology - February 7, 2016 Category: Neurology Authors: Holder, D., Jickling, G. Tags: IV-tPA and Endovascular Therapy Source Type: research

A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T > C Mutation in the Mitochondrial MTND3 Gene
Conclusion The m.10191T>C mutation in the mtDNA of the complex I (CI) subunit of MTND3 results in the substitution of a highly conserved amino acid (p.Ser45Pro) within the ND3 protein, leading to CI dysfunction through impaired enzyme catalysis rather than impaired stability or assembly, causing a broad clinical spectrum of disorders (26). Patients with the m.10191T>C mutation are rare. In the present study, we report on a family of patients with the extremely rare adult-onset Leigh-like syndrome with the m.10191T>C mutation. Including the two patients from our reported family, the m.10191T...
Source: Frontiers in Neurology - April 17, 2019 Category: Neurology Source Type: research

Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships
In conclusion, a complex of clinical, radiological, and laboratory manifestations of stroke-like onset of CJD is outlined. The clinical relationships between CJD and stroke are considered, in an attempt to highlight this rare presentation of an uncommon disease.
Source: Frontiers in Neurology - February 25, 2021 Category: Neurology Source Type: research

Arteria vertebralis thrombosis egy 7 éves gyermekben
We present the case history of a 7-year-old boy who was admitted to the pediatric intensive care unit of a county hospital with symptoms of facial palsy, progrediating ataxia and somnolence. Contrast-enhanced angiographic MR images of the skull revealed acute ischemic lesions and suggested stenosis of the left vertebral artery, then it was confirmed by TOF (time of flight) angiography of vessels of the neck and cervical ultrasound examination. The arterial thrombus causing ischaemia was eliminated by drug treatment and the rehabilitation process could be started. The patient's condition improved considerably following that...
Source: Orvosi Hetilap - November 21, 2021 Category: General Medicine Authors: Alexandra Viczei Istv án Lapis Ádám Marián Brzózka Gy örgy Szeifert Source Type: research

Vertebral artery thrombosis in a 7-year-old child
We present the case history of a 7-year-old boy who was admitted to the pediatric intensive care unit of a county hospital with symptoms of facial palsy, progrediating ataxia and somnolence. Contrast-enhanced angiographic MR images of the skull revealed acute ischemic lesions and suggested stenosis of the left vertebral artery, then it was confirmed by TOF (time of flight) angiography of vessels of the neck and cervical ultrasound examination. The arterial thrombus causing ischaemia was eliminated by drug treatment and the rehabilitation process could be started. The patient's condition improved considerably following that...
Source: Orvosi Hetilap - November 21, 2021 Category: General Medicine Authors: Alexandra Viczei Istv án Lapis Ádám Marián Brzózka Gy örgy Szeifert Source Type: research