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Low Incidence of Paravalvular Leakage With the Balloon-Expandable Sapien 3 Transcatheter Heart Valve.
CONCLUSIONS: The present study shows excellent clinical and hemodynamic outcomes of high-risk transapical valve replacement patients treated with the new S3 THV. The S3 THV shows a low incidence of postoperative aortic regurgitation, with 98% presenting with less than mild aortic regurgitation. PMID: 26117587 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - June 24, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Wendt D, Al-Rashid F, Kahlert P, Eißmann M, El-Chilali K, Janosi A, Pasa S, Tsagakis K, Liakopoulos O, Erbel R, Jakob H, Thielmann M Tags: Ann Thorac Surg Source Type: research

Low Incidence of Paravalvular Leakage With the Balloon-Expandable Sapien 3 Transcatheter Heart Valve
Conclusions The present study shows excellent clinical and hemodynamic outcomes of high-risk transapical valve replacement patients treated with the new S3 THV. The S3 THV shows a low incidence of postoperative aortic regurgitation, with 98% presenting with less than mild aortic regurgitation.
Source: The Annals of Thoracic Surgery - June 24, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Transapical Transcatheter Aortic Valve Implantation Using the JenaValve: A One-Year Follow-up.
Conclusion The JenaValve transapical TAVI system is a safe and feasible procedure with low peri- and postoperative complications and convincing midterm performance of the prosthesis. PMID: 26030120 [PubMed - as supplied by publisher]
Source: The Thoracic and Cardiovascular Surgeon - June 1, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Reuthebuch O, Koechlin L, Kaufmann BA, Kessel-Schaefer A, Gahl B, Eckstein FS Tags: Thorac Cardiovasc Surg Source Type: research

Transapical Transcatheter Aortic Valve Implantation Using the JenaValve: A One-Year Follow-up
Conclusion The JenaValve transapical TAVI system is a safe and feasible procedure with low peri- and postoperative complications and convincing midterm performance of the prosthesis.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text
Source: The Thoracic and Cardiovascular Surgeon - June 1, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Reuthebuch, OliverKoechlin, LucaKaufmann, Beat A.Kessel-Schaefer, ArnheidGahl, BrigittaEckstein, Friedrich S. Tags: Original Cardiovascular Source Type: research

Outcomes of Treatment of Nonagenarians With Severe Aortic Stenosis.
CONCLUSIONS: Treatment of AS approximates natural life expectancy in select nonagenarians, with no significant difference in long-term survival between SAVR and TAVR. Importantly, patient quality of life improved at 1 year. With appropriate selection, nonagenarians with severe AS can benefit from treatment. PMID: 26013708 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - May 23, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Mack MC, Szerlip M, Herbert MA, Akram S, Worley C, Kim RJ, Prince BA, Harrington KB, Mack MJ, Holper EM Tags: Ann Thorac Surg Source Type: research

Outcomes of Treatment of Nonagenarians With Severe Aortic Stenosis
Conclusions Treatment of AS approximates natural life expectancy in select nonagenarians, with no significant difference in long-term survival between SAVR and TAVR. Importantly, patient quality of life improved at 1 year. With appropriate selection, nonagenarians with severe AS can benefit from treatment.
Source: The Annals of Thoracic Surgery - May 23, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Thirty-day VARC-2 and performance data of a new self-expanding transcatheter aortic heart valve.
CONCLUSIONS: In this first-in-human study, the feasibility of implantation of the BIOVALVE system and its re-sheathing functionality was demonstrated, and short-term safety data were encouraging. Larger studies are required to confirm the performance of the device. PMID: 25983028 [PubMed - as supplied by publisher]
Source: EuroIntervention - May 21, 2015 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Early and late outcomes of AVR with aortic annular enlargement in octogenarian
Conclusion AVR with aortic annular enlargement in octogenarians with small aortic annulus was safe and led to good operative and long-term outcomes.
Source: General Thoracic and Cardiovascular Surgery - May 14, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Preliminary outcomes after transcatheter aortic valve implantation in patients with systemic sclerosis.
CONCLUSIONS: The present case series suggests that the TAVI procedure is feasible in patients with SSc and severe AS. PMID: 25912392 [PubMed - in process]
Source: EuroIntervention - May 1, 2015 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

The paradox of surgical management of patients with low-flow, low-gradient aortic stenosis
In this issue of the Journal, Parikh and colleagues1 elegantly analyze the institutional outcomes of aortic valve replacement (AVR) at the Cleveland Clinic to illustrate the potential impact of low-flow, low-gradient aortic stenosis (LFLGAS) on 5-year post-AVR mortality. Despite quite acceptable initial operative outcomes, a fifth of their 875 consecutive patients who underwent surgical AVR for severe stenosis during a 2-year period were dead at 5 years. Preoperative left ventricular stroke volume index (LVSVI) was used to identify both LFLGAS with low ejection fraction (EF) and paradoxic LFLGAS with an EF of 50% or greater.
Source: The Journal of Thoracic and Cardiovascular Surgery - March 21, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Vinay Badhwar, John S. Ikonomidis, Jeffrey P. Jacobs Tags: Editorial commentary Source Type: research

Anaesthetic management of transcatheter aortic valve implantation: results from the Italian CoreValve registry.
CONCLUSIONS: Our study indicates that, in experienced centres which have gone beyond their initial learning curve with TAVI, the use of local anaesthesia in a selected patient population can be associated with good clinical outcomes. Nevertheless, as severe procedural complications are possible, an anaesthesiologist should always be present as part of the team. PMID: 25772903 [PubMed - as supplied by publisher]
Source: EuroIntervention - March 20, 2015 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Outcomes of surgical aortic valve replacement for severe aortic stenosis: Incorporation of left ventricular systolic function and stroke volume index
We sought to a) assess predictors of mortality in consecutive patients with severe aortic stenosis (AS) undergoing aortic valve replacement (AVR) and b) determine if there are differences in mortality, separated on the basis of different AS subtypes and left ventricular stroke volume index (LV-SVI).
Source: The Journal of Thoracic and Cardiovascular Surgery - March 11, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Roosha Parikh, Andrew L. Goodman, Tyler Barr, Joseph F. Sabik, Lars G. Svensson, L Leonardo Rodriguez, Bruce W. Lytle, Richard A. Grimm, Brian P. Griffin, Milind Y. Desai Source Type: research

A Randomized Multicenter Trial of Minimally Invasive Rapid Deployment Versus Conventional Full Sternotomy Aortic Valve Replacement
Conclusions RDAVR by the MIS approach is associated with significantly reduced myocardial ischemic time and better valvular hemodynamic function than FS-AVR with a conventional stented bioprosthesis. Rapid deployment valves may facilitate the performance of MIS-AVR.
Source: The Annals of Thoracic Surgery - December 30, 2014 Category: Cardiovascular & Thoracic Surgery Source Type: research

Single-centre experience with next-generation devices for transapical aortic valve implantation ADULT CARDIAC
CONCLUSIONS In a real-world clinical setting, next-generation transapical THV yielded positive haemodynamic results. The incidence of relevant paravalvular regurgitation was scarce in this group and clinical outcomes were encouraging during short-term follow-up. Long-term follow-up is required to investigate the durability of these new devices.
Source: European Journal of Cardio-Thoracic Surgery - December 11, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Seiffert, M., Conradi, L., Kloth, B., Koschyk, D., Schirmer, J., Schnabel, R. B., Blankenberg, S., Reichenspurner, H., Diemert, P., Treede, H. Tags: Electrophysiology - arrhythmias, Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Transcatheter aortic valve implantation using a direct aortic approach: a single-centre Heart Team experience
CONCLUSIONS The TAo TAVI approach is feasible and offers a safe alternative for patients in whom a transfemoral approach is not feasible or desirable.
Source: Interactive CardioVascular and Thoracic Surgery - October 24, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Amrane, H., Porta, F., van Boven, A. J., Boonstra, P. W., Hofma, S. H., Head, S. J., Kappetein, A. P. Tags: Transplantation - heart, Basic research vascular Adult Cardiac Source Type: research

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