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MiR-18a inhibits BMP4 and HIF-1 α Normalizing Brain Arteriovenous Malformations.
Conclusions: MiR-18a may have significant clinical value in preventing, reducing and potentially reversing AVM. PMID: 32755283 [PubMed - as supplied by publisher]
Source: Circulation Research - August 4, 2020 Category: Cardiology Authors: Marín-Ramos NI, Thein TZ, Ghaghada KB, Chen TC, Giannotta SL, Hofman F Tags: Circ Res Source Type: research

Subclinical atherosclerotic calcification and cognitive functioning in middle-aged adults: The CARDIA study
We examined the association of coronary artery and abdominal aortic calcified plaque (CAC and AAC, respectively) with cognitive functioning in middle-aged adults.Methods: This cross-sectional study included 2510 black and white adults (age: 43–55 years) without heart disease or stroke who completed a year 25 follow-up exam (2010–11) as part of the Coronary Artery Risk Development in Young Adults Study. CAC and AAC were measured with non-contrast computed tomography. Cognition was assessed with the Digit Symbol Substitution Test (DSST) (psychomotor speed), Stroop Test (executive function), and Rey Auditory Verbal Learni...
Source: Atherosclerosis - October 14, 2013 Category: Cardiology Authors: Jared P. Reis, Lenore J. Launer, James G. Terry, Catherine M. Loria, Adina Zeki Al Hazzouri, Stephen Sidney, Kristine Yaffe, David R. Jacobs, Christopher T. Whitlow, Na Zhu, J. Jeffrey Carr Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research