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Evaluation of an online intervention for improving stroke survivors ’ health-related quality of life: A randomised controlled trial
ConclusionsThe P2S online healthy lifestyle program improved stroke survivors ’ self-reported global ratings of HRQoL (as measured by EQ-VAS) at 6-month follow-up. Online platforms represent a promising tool to engage and support some stroke survivors. Trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12617001205325.
Source: PLoS Medicine - April 19, 2022 Category: Internal Medicine Authors: Ashleigh Guillaumier Source Type: research

Plant-based diets and incident cardiovascular disease and all-cause mortality in African Americans: A cohort study
ConclusionsIn this study of black Americans, we observed that, unlike in prior studies, greater adherence to a plant-based diet was not associated with CVD or all-cause mortality.
Source: PLoS Medicine - January 5, 2022 Category: Internal Medicine Authors: Leah J. Weston Source Type: research

Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
by Yuan Zhang, Hongxi Yang, Shu Li, Wei-dong Li, Yaogang Wang BackgroundPrevious studies have revealed the involvement of coffee and tea in the development of stroke and dementia. However, little is known about the association between the combination of coffee and tea and the risk of stroke, dementia, and poststroke dementia. Therefore, we aimed to investigate the associations of coffee and tea separately and in combination with the risk of developing stroke and dementia. Methods and findingsThis prospective cohort study included 365,682 participants (50 to 74 years old) from the UK Biobank. Participants joined the study f...
Source: PLoS Medicine - November 16, 2021 Category: Internal Medicine Authors: Yuan Zhang Source Type: research

Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study
We examined the associations between DSR and subsequent total and cause-specific mortality among 451,390 adults enrolled in the European Prospective Investigation into Cancer and Nutrition (EPIC) study (1992 to 2014, median follow-up: 17 years), free of cancer, diabetes, heart attack, or stroke at baseline. Usual dietary intakes were assessed at recruitment with country-specific dietary questionnaires (DQs). DSR of an individual ’s yearly diet was calculated based on the absolute number of unique biological species in each (composite) food and drink. Associations were assessed by fitting multivariable-adjusted Cox propor...
Source: PLoS Medicine - October 18, 2021 Category: Internal Medicine Authors: Giles T. Hanley-Cook Source Type: research

Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study
This study investigated associations between risk factors and late-life cognitive decline on a global scale, including comparisons between ethno-regional groups. Methods and findingsWe harmonized longitudinal data from 20 population-based cohorts from 15 countries over 5 continents, including 48,522 individuals (58.4% women) aged 54 –105 (mean = 72.7) years and without dementia at baseline. Studies had 2–15 years of follow-up. The risk factors investigated were age, sex, education, alcohol consumption, anxiety, apolipoprotein E ε4 allele (APOE*4) status, atrial fibrillation, blood pressure and pulse pressure, body mas...
Source: PLoS Medicine - July 22, 2019 Category: Internal Medicine Authors: Darren M. Lipnicki Source Type: research

Metabolic syndrome and risk of Parkinson disease: A nationwide cohort study
by Ga Eun Nam, Seon Mee Kim, Kyungdo Han, Nan Hee Kim, Hye Soo Chung, Jin Wook Kim, Byoungduck Han, Sung Jung Cho, Ji Hee Yu, Yong Gyu Park, Kyung Mook Choi BackgroundThe association of metabolic syndrome (MetS) with the development of Parkinson disease (PD) is currently unclear. We sought to determine whether MetS and its components are associated with the risk of incident PD using large-scale cohort data for the whole South Korean population. Methods and findingsHealth checkup data of 17,163,560 individuals aged ≥40 years provided by the National Health Insurance Service (NHIS) of South Korea between January 1, 2009, a...
Source: PLoS Medicine - August 21, 2018 Category: Internal Medicine Authors: Ga Eun Nam Source Type: research

Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study
ConclusionsThe importance of specific midlife factors in disease progression, from disease-free state to single disease, multimorbidity, and death, varies depending on the disease stage. While clinical risk factors at age 50 determine the risk of incident cardiometabolic disease in a disease-free population, midlife socioeconomic and behavioural factors are stronger predictors of progression to multimorbidity and mortality in people with cardiometabolic disease.
Source: PLoS Medicine - May 21, 2018 Category: Internal Medicine Authors: Archana Singh-Manoux Source Type: research

The current and potential health benefits of the National Health Service Health Check cardiovascular disease prevention programme in England: A microsimulation study
ConclusionsOur model indicates that the current NHS Health Check programme is contributing to improvements in health and reducing health inequalities. Feasible changes in the organisation of the programme could result in more than a 3-fold increase in health benefits.
Source: PLoS Medicine - March 6, 2018 Category: Internal Medicine Authors: Oliver T. Mytton Source Type: research

Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies
by Germ án D. Carrasquilla, Paolo Frumento, Anita Berglund, Christer Borgfeldt, Matteo Bottai, Chiara Chiavenna, Mats Eliasson, Gunnar Engström, Göran Hallmans, Jan-Håkan Jansson, Patrik K. Magnusson, Peter M. Nilsson, Nancy L. Pedersen, Alicja Wolk, Karin Leander BackgroundRecent research indicates a favourable influence of postmenopausal hormone therapy (HT) if initiated early, but not late, on subclinical atherosclerosis. However, the clinical relevance of timing of HT initiation for hard end points such as stroke remains to be determined. Further, no previous research has considered the timing of initiation of HT i...
Source: PLoS Medicine - November 17, 2017 Category: Internal Medicine Authors: Germ án D. Carrasquilla Source Type: research