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Cerebral fungal infections as a cause of stroke in cardiac surgery patients: Be Cautious!!
Neurological dysfunction in the postoperative period following cardiac surgery is most commonly attributed to thromboembolism or an intracranial bleed. Fungal infection is a rare cause of cerebral infarction and hemiparesis in an otherwise healthy patient. Cerebral Aspergillus infections are common in immunocompromised patients and is not considered as the first-line differential diagnosis of cerebral infarcts in a cardiac surgery patient. The infection is usually a secondary from lung, paranasal sinuses, or heart and forms microthrombi in large or medium sized cerebral vessels.
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 30, 2023 Category: Anesthesiology Authors: Avneet Singh, Arushi Goyal, Manpreet Singh, Sidharth Garg, Sandeep Moudgil, Vipin Gupta Tags: Letter to the Editor Source Type: research

Pentraxin 3 in Cardiovascular Disease
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research

Pediatric cavernous sinus thrombosis: A case series and review of the literature
Conclusion: Our case series demonstrates low morbidity and mortality with early, aggressive surgical, antimicrobial, and anticoagulation therapies. Although anticoagulation and surgery were not associated with significantly different outcomes, more study is needed.
Source: Neurology - August 31, 2015 Category: Neurology Authors: Smith, D. M., Vossough, A., Vorona, G. A., Beslow, L. A., Ichord, R. N., Licht, D. J. Tags: Childhood stroke, Secondary headache disorders, Pediatric headache, All Imaging, Cerebral venous thrombosis ARTICLE Source Type: research