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Specialty: Neurosurgery
Condition: Thrombosis
Education: Study

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Total 317 results found since Jan 2013.

O-012 Acute clot formation on the surface of flow diverters can be reduced by using phosphoryl-choline surface modification
Conclusion Our preliminary study supported our hypothesis that using phosphoryl-choline surface modified flow diverter can be useful to decrease the occurrence of micro-clot formation, especially post-angioplasty. Importantly, S-PED reduced clot formation at the origin of covered side-branches. References . AJNR 2015;36:98–107. . J. Neurosurg 2016;1–6. Disclosures M. Marosfoi: None. F. Clarencon: None. E. Langan: None. R. King: None. O. Brooks: None. T. Tamura: None. M. Gounis: 1; C; Medtronic Neurovascular. A. Puri: 1; C; Medtronic Neurovascular.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Marosfoi, M., Clarencon, F., Langan, E., King, R., Brooks, O., Tamura, T., Gounis, M., Puri, A. Tags: Oral Abstracts Source Type: research

O-030 Aspiration catheter with extension tip exhibits improved suction
Conclusion The Mi-R4Q demonstrates a substantial increase in aspiration catheter capability by applying known relationships in Fluid Dynamics to more effectively convey vacuum and aspirate fluid than anything else currently on the market. Simulated use validates effectiveness of design and paves the way for in-vivo study. Disclosures A. Halaszyn: 1; C; MIVI Neuroscience Inc. A. Berenstein: 6; C; MIVI Neuroscience Inc.. T. Shigematsu: None. P. Coletti: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Halaszyn, , Berenstein, A., Shigematsu, T., Coletti, P. Tags: Oral Abstracts Source Type: research

E-018 Post endovascular treatment of acute vertebro-basilar stroke: anticoagulation versus antiplatelet therapy
Conclusion Preliminary analysis of this ongoing systematic review did not show any differences in outcome or hemorrhagic complications in patients with AVBS on APT versus ACT post intervention. Either modality of treatment was superior to no treatment with a higher risk of hemorrhagic complications. Disclosures M. Weber: None. N. Khan: None. F. Siddiqui: None. J. Blessman: None. A. Elias: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Weber, M., Khan, N., Siddiqui, F., Blessman, J., Elias, A. Tags: Electronic Poster Abstracts Source Type: research

E-077 Laboratory analogs of challenging thromboemboli in acute ischemic stroke
Conclusion Thrombus analogs with mechanical characteristics similar to those of challenging clinical thrombi were successfully developed. The calcium apatite thrombus analog was found to be stiffer than the fibrin-rich thrombus analog. References . Saver JL et al: Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015, 372(24):2285–2295. . Dorn F et al: Endovascular treatment of acute intracerebral artery occlusions with the solitaire stent: single-centre experience with 108 recanalization procedures. Cerebrovasc Dis 2012, 34(1):70–77. Disclosures: J. Chueh: None. J....
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Chueh, J., Litchman, J., Arslanian, R., Carniato, S., Rex, D., Howk, M., Gounis, M., Puri, A. Tags: Electronic Poster Abstracts Source Type: research

E-088 Investigation of safety termination of antiplatelet therapy after lvis stent-assisted cerebral aneurysm coiling
Conclusion Termination of AT at 3 months postoperatively did not result in ischemic events among patients who underwent LSAC. Neointimal formation of Lvis stent may be a criterion for termination of AT without increasing the risk of ischemic event. Disclosures: K. Takayama: None. K. Myouchin: None. T. Wada: None. S. Kurokawa: None. K. Kichikawa: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Takayama, K., Myouchin, K., Wada, T., Kurokawa, S., Kichikawa, K. Tags: Electronic Poster Abstracts Source Type: research

Effective use of balloon guide catheters in reducing incidence of mechanical thrombectomy related distal embolization
ConclusionsThe risk of distal embolization was significantly decreased with the use of a BGC.
Source: Acta Neurochirurgica - July 9, 2017 Category: Neurosurgery Source Type: research

The natural progression of VGAMs and the need for urgent medical attention: a systematic review and meta-analysis
Conclusions Over time, the rate of preoperative sudden death in patients with VGAM gradually declined and the rate of emergency operations gradually increased. The outcome of patients with early spontaneous thromboses was good. Our study provides a definitive description of the natural progression of VGAMs and the need for urgent medical attention.
Source: Journal of NeuroInterventional Surgery - May 30, 2017 Category: Neurosurgery Authors: Yan, J., Gopaul, R., Wen, J., Li, X.-s., Tang, J.-f. Tags: Hemorrhagic stroke Source Type: research

Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome: a systematic review
Conclusions The hyperdense artery sign is associated with RBC-rich thrombi and improved recanalization rates. However, there was no association between the histopathological characteristics of thrombi and stroke etiology and angiographic outcomes.
Source: Journal of NeuroInterventional Surgery - May 30, 2017 Category: Neurosurgery Authors: Brinjikji, W., Duffy, S., Burrows, A., Hacke, W., Liebeskind, D., Majoie, C. B. L. M., Dippel, D. W. J., Siddiqui, A. H., Khatri, P., Baxter, B., Nogeuira, R., Gounis, M., Jovin, T., Kallmes, D. F. Tags: Editor''s choice, Ischemic stroke Source Type: research

Neuroprotective strategies and the underlying molecular basis of cerebrovascular stroke.
Abstract Stroke is a leading cause of disability in the US. Although there has been significant progress in the area of medical and surgical thrombolytic technologies, neuroprotective agents to prevent secondary cerebral injury and to minimize disability remain limited. Only limited success has been reported in preclinical and clinical trials evaluating a variety of compounds. In this review, the authors discuss the most up-to-date information regarding the underlying molecular biology of stroke as well as strategies that aim to mitigate this complex signaling cascade. Results of historical research trials involvi...
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Karsy M, Brock A, Guan J, Taussky P, Kalani MY, Park MS Tags: Neurosurg Focus Source Type: research

Combined proximal balloon occlusion and distal aspiration: a new approach to prevent distal embolization during neurothrombectomy
Conclusions A combination of proximal internal carotid artery occlusion using a balloon catheter and distal aspiration through an intermediate catheter represents a safe and efficient adjunct to mechanical thrombectomy with stent retrievers. In our patient cohort, no new thrombembolic complications were detected.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Stampfl, S., Pfaff, J., Herweh, C., Pham, M., Schieber, S., Ringleb, P. A., Bendszus, M., Möhlenbruch, M. A. Tags: Ischemic stroke Source Type: research

Active push deployment technique improves stent/vessel-wall interaction in endovascular treatment of acute stroke with stent retrievers
Conclusions The APD technique improves apposition of the tested devices to the vessel wall. The widening effect comes at the cost of minimal shortening of the devices. Our clinical experience shows that using the APD technique to deploy the Trevo device is effective and safe.
Source: Journal of NeuroInterventional Surgery - February 13, 2017 Category: Neurosurgery Authors: Wiesmann, M., Brockmann, M.-A., Heringer, S., Müller, M., Reich, A., Nikoubashman, O. Tags: Ischemic stroke Source Type: research

Management and outcome of spontaneous cerebral venous sinus thrombosis in a 5-year consecutive single-institution cohort
Conclusions In our series, the majority (92.9%) of patients with spontaneous dural sinus thrombosis had a favorable clinical outcome as defined by a mRS ≤2. Further prospective studies are needed to study the impact of anticoagulation on the clinical course of the disease.
Source: Journal of NeuroInterventional Surgery - December 13, 2016 Category: Neurosurgery Authors: Lee, D. J., Ahmadpour, A., Binyamin, T., Dahlin, B. C., Shahlaie, K., Waldau, B. Tags: Hemorrhagic stroke Source Type: research

Mid-term and long-term follow-up of intracranial aneurysms treated by the p64 Flow Modulation Device: a multicenter experience
Conclusions Endovascular treatment with the p64 Flow Modulation Device is a safe treatment for unruptured cerebral aneurysms, resulting in a high rate of occlusion. As with other flow diverter devices, we recommend this treatment mainly for large-necked aneurysms of the internal carotid artery siphon. However, endovascular treatment with the p64 device should also be encouraged in difficult cases such as aneurysms of the posterior circulation and beyond the circle of Willis.
Source: Journal of NeuroInterventional Surgery - December 13, 2016 Category: Neurosurgery Authors: Briganti, F., Leone, G., Ugga, L., Marseglia, M., Macera, A., Manto, A., Delehaye, L., Resta, M., Resta, M., Burdi, N., Nuzzi, N. P., Divenuto, I., Caranci, F., Muto, M., Solari, D., Cappabianca, P., Maiuri, F. Tags: Open access, New devices Source Type: research

Neck vessel dissection following whiplash-type neck injury
Arterial dissection is a recognised complication of neck manipulation and trauma. In a systematic audit of 148 complex medicolegal whiplash cases 131 had only neck pain, 8 had radiculopathic symptoms, and 9 had symptoms and signs suggesting an arterial dissection of a neck vessel with presumed secondary thromboembolism. Their ages ranged from 28–55. Three had hemipareses supported by scan abnormalities, and one had a probable posterior fossa stroke. Five cases had prolonged symptoms without imaging abnormalities. This series cannot be considered representative of whiplash cases as a whole. The dissection is necessari...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Peatfield, R., Jenkins, H. Tags: Pain (neurology), Stroke, Trauma, Injury ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Revisiting the NIH Stroke Scale as a screening tool for proximal vessel occlusion: can advanced imaging be targeted in acute stroke?
Conclusions In this cohort, specific NIHSS criteria were highly sensitive for emergent large vessel occlusion and, if validated, may allow for clinical screening prior to advanced imaging with CT angiography.
Source: Journal of NeuroInterventional Surgery - November 14, 2016 Category: Neurosurgery Authors: Moore, R. D., Jackson, J. C., Venkatesh, S. L., Quarfordt, S. D., Baxter, B. W. Tags: Ischemic stroke Source Type: research