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Condition: Thrombosis
Drug: Estradiol

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Total 151 results found since Jan 2013.

Hormonal therapies in females with blood disorders: thrombophilia, thrombosis, hemoglobinopathies, and anemias
Res Pract Thromb Haemost. 2023 Apr 24;7(4):100161. doi: 10.1016/j.rpth.2023.100161. eCollection 2023 May.ABSTRACTThere is widespread use of gonadal steroid hormone therapy for a variety of indications throughout the reproductive and postreproductive lifespan. These therapies may have particular benefits and specific risk among those with blood disorders, including inherited or acquired bleeding disorders, thrombophilia, thrombosis, or anemia. This clinical review is intended to provide a guidance for counseling and management of adolescent and adult biologic females with thrombophilic risk factors and/or thrombosis who req...
Source: Thrombosis and Haemostasis - June 5, 2023 Category: Hematology Authors: Maureen K Baldwin Bethany Samuelson Bannow Rachel P Rosovsky Nancy Sokkary Lakshmi V Srivaths Source Type: research

Hormones and thrombosis: the dark side of the moon
We describe physio-pathological changes occurring during the administration of hormonal therapies. Furthermore, we analyze the risk of venous and arterial thrombosis associated with different products, routes of administration and additional risk factors. New hormonal preparations, such as estradiol combined with dienogest, as well as non-oral hormonal therapies, are suggested to decrease thrombotic risk significantly.DISCUSSION: The availability of many products and different routes of administration allow most women to use safely contraception, as well as HRT. We encourage careful counselling instead of inflexible or fea...
Source: Blood Transfusion - May 26, 2023 Category: Hematology Authors: Doris Barcellona Elvira Grandone Francesco Marongiu Source Type: research