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Exploring the Recent Trends in Management of Dementia and Frailty: Focus on Diagnosis and Treatment
Curr Med Chem. 2022 Apr 8. doi: 10.2174/0929867329666220408102051. Online ahead of print.ABSTRACTDementia and frailty increase health adversities in older adults, which are topics of growing research interest. Frailty is considered to correspond to a biological syndrome associated with age. Frail patients may ultimately develop multiple dysfunctions across several systems, including stroke, transient ischemic attack, vascular dementia, Parkinson's disease, Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, cortico-basal degeneration, multiple system atrophy, amyotrophic lateral sclerosis, and Creutzfe...
Source: Current Medicinal Chemistry - April 11, 2022 Category: Chemistry Authors: Md Mominur Rahman Sadia Afsana Mim Md Rezaul Islam Anwar Parvez Fahadul Islam Mohammad Borhan Uddin Md Saidur Rahaman Pollob Ahmed Shuvo Muniruddin Ahmed Nigel H Greig Mohammad Amjad Kamal Source Type: research

Role Of Glp-1 Analogs In The Management Of Diabetes And Its Secondary Complication
Mini Rev Med Chem. 2021 Apr 21. doi: 10.2174/1389557521666210422114909. Online ahead of print.ABSTRACTThe cardiovascular complications of type 2 diabetes mellitus (T2DM) include myocardial infarction, heart failure, peripheral vascular disease and, stroke and retinopathy, nephropathy and neuropathy are microvascular complications. While the newer therapies like glitazones or even dipeptidyl-peptidase-IV (DPP-IV) inhibitors increase the risk of therapy, the Glucagon Like Peptide-1 Receptor Agonists (GLP-1RAs), were reported as suitable alternates. The GLP-1RAs reduce the major adverse cardiovascular events (MACE), have anti...
Source: Mini Reviews in Medicinal Chemistry - April 23, 2021 Category: Chemistry Authors: Ponnurengam Malliappan Sivakumar B Premkumar Prabhawathi Veluchamy Pranav Kumar Prabhakar Source Type: research