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Nontraumatic spontaneous intracerebral hemorrhage: Baseline characteristics and early outcomes
ConclusionThe present study showed that SICH is a serious disease causing high mortality and disability, particularly in the early period after event.
Source: Brain and Behavior - January 12, 2020 Category: Neurology Authors: Mohamed Al ‐Khaled, Samer Awwad, Toralf Brüning Tags: ORIGINAL RESEARCH Source Type: research

Codeine is associated with poor prognosis in acute stroke
ConclusionUse of codeine‐containing analgesics is associated with a poorer short‐term prognosis and an increased occurrence of complications in the acute phase after a stroke. The highly significant findings suggest that codeine has a negative effect on acute stroke patients. The study reflects exploratory analyses and prospective studies are necessary to determine the background of the association observed in our study. Use of codeine‐containing analgesics is associated with a poorer short‐term prognosis and an increased occurrence of complications in the acute phase after a stroke. The highly significant finding...
Source: Brain and Behavior - November 19, 2017 Category: Neurology Authors: Stian T. Ryste, Bernt A. Engelsen, Halvor Naess Tags: ORIGINAL RESEARCH Source Type: research

Nuclear factor-¿B activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research

Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research

Diffuse cerebral petechial hemorrhage in an 8-year-old girl with MRSA pneumonia and sepsis
An 8-year-old girl in septic shock due to necrotizing methicillin-resistant Staphylococcus aureus (MRSA) pneumonia developed signs of end-organ damage, new right hemiplegia, and left gaze preference. Susceptibility-weighted MRI demonstrated extensive multifocal petechial hemorrhage preferentially at the gray–white matter interface due to septic microemboli (figure). Mechanisms of hemorrhage include small-vessel occlusion leading to mycotic aneurysm formation with rupture or pyogenic arteritis without aneurysm formation.1 Intracranial hemorrhage associated with metastatic staphylococcal infections is rarely descr...
Source: Neurology - January 20, 2014 Category: Neurology Authors: Williams, M. T., Jiang, H. Tags: All Imaging, Bacterial infections, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, Intracerebral hemorrhage NEUROIMAGES Source Type: research