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The battle against malaria in Africa has stalled. Can research in Mozambique explain why?
.news-article__hero--featured .parallax__element{ object-position: 45% 50%; -o-object-position: 45% 50%; } .news-article__figure.inset { float: right !important; width: 33%; margin: 0.5rem 0 0.5rem 1rem; } @media (min-width: 576px) { .news-article__figure.inset { width: 25%; margin: 0.5rem 0 0.5rem 2rem; } } @media (min-width: 768px) { .news-article__figure.inset { width: 40%; margin: 0.5rem 0 0.5rem 1rem; } } Moisés Mapanga, a burly man of 49, is the bait. At 6 p.m. on a mid-April evening, he climbs into an orange tent outside his one-room house in Matutuíne, a hot, swampy district near Maputo, the cap...
Source: Science of Aging Knowledge Environment - September 8, 2022 Category: Geriatrics Source Type: research

The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection
Conclusion In conclusion, our data show that R. rickettsii exerts a modulatory effect on the transcriptional profile the SG of A. aureolatum. Moreover, RNAi experiments demonstrated that the knockdown of one microplusin increases the susceptibility of ticks to infection, suggesting that this is one important factor for the control of R. rickettsii. The functional characterization of the additional CDSs modulated by infection is warranted and might reveal other factors that interfere with the acquisition and/or transmission of this tick-borne pathogen. Ethics Statement All procedures involving vertebrate animals were car...
Source: Frontiers in Physiology - May 2, 2019 Category: Physiology Source Type: research