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E-023 Predictors of outcomes in tandem anterior circulation occlusions following mechanical thrombectomy
In this study, we present outcomes of patients undergoing tandem mechanical thrombectomy. We demonstrate that stenting is associated with improved final reperfusion, but increased odds of asymptomatic ICH. Additional clinical trials should be performed to optimize the procedure and improve patient outcomes.Disclosures J. Catapano: None. D. Farhadi: None. A. Naik: None. S. Koester: None. E. Winkler: None. V. Srinivasan: None. K. Karahalios: None. J. Rulney: None. S. Desai: None. A. Jadhav: None. F. Albuquerque: None. A. Ducruet: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Catapano, J., Farhadi, D., Naik, A., Koester, S., Winkler, E., Srinivasan, V., Karahalios, K., Rulney, J., Desai, S., Jadhav, A., Albuquerque, F., Ducruet, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-092 Use of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients
ConclusionUse of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients.Disclosures A. Baig: None. J. Neumaier: None. M. Waqas: None. A. Monteiro: None. J. Cappuzzo: None. W. Khawar: None. B. Donnelly: None. E. Levy: 2; C; : Claret Medical, GLG Consulting, Guidepoint Global, Imperial Care, Medtronic, Rebound, StimMed, Misionix, Mosiac, Clarion, IRRAS. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care, Rebound Therapeutics, StimMed, Three Ri...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Baig, A., Neumaier, J., Waqas, M., Monteiro, A., Cappuzzo, J., Khawar, W., Donnelly, B., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-139 Use of drug-eluding, balloon-expandable resolute onyx coronary stent as a new treatment strategy for vertebral artery ostial stenosis
ConclusionWe report the first clinical series investigating the use of drug-eluding, balloon-expandable Resolute Onyx coronary stent as a safe, efficacious, and durable treatment option for both symptomatic and asymptomatic vertebral ostial stenosis.Disclosures J. Lim: None. A. Baig: None. A. Aguirre: None. A. Monteiro: None. E. Levy: 2; C; : Claret Medical, GLG Consulting, Guidepoint Global, Imperial Care, Medtronic, Rebound, StimMed, Misionix, Mosiac, Clarion, IRRAS.. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care, Rebound Therapeutics, StimMed, Three Rivers Medical. A. Siddiqu...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lim, J., Baig, A., Aguirre, A., Monteiro, A., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-153 Transfemoral flow-reversal using walrus balloon-guide catheter for carotid artery stenting technical description and single-center experience
ConclusionsIn our institution’s experience, this technique was safe, feasible and efficient, with 100% technical success and no periprocedural thromboembolic complications. More extensive studies are needed to establish the role of proximal protection with flow-reversal using modern BGCs.Disclosures J. Cappuzzo: None. A. Monteiro: None. M. Waqas: None. A. Baig: None. D. Popoola: None. F. Almayman: None. W. Khawar: None. Z. Farkash: None. A. Siddiqui: 2; C; Amnis Therapeutics, Apellis Pharmaceuticals, Inc., Boston Scientific, Canon Medical Systems USA, Inc., Cardinal Health 200, LLC, Cerebrotech Medical Systems, Inc.,...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Cappuzzo, J., Monteiro, A., Waqas, M., Baig, A., Popoola, D., Almayman, F., Khawar, W., Farkash, Z., Siddiqui, A., Levy, E., Snyder, K. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-187 Pipeline embolization stent for treatment of giant supraclinoid aneurysms: a case series
ConclusionThe Pipeline embolization device is a novel technique that can be utilized for treatment of giant cerebrovascular aneurysms with emerging evidence of immediate and long-term success. Further patient enrollment and clinical trials will be required to assess its efficacy in comparison to other endovascular and surgical approaches for the treatment of giant aneurysms.Disclosures M. Fana: None. O. Alsrouji: None. M. Rehman: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fana, M., Alsrouji, O., Rehman, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

O-052 The pennsylvania post-market multicenter experience with flow re-direction endoluminal device (FRED)
ConclusionThe results of the early post-market experience with the FRED device show reasonable safety and adequate aneurysmal occlusion rates comparable to other flow diverters. However, more extensive multicenter studies with more extended follow-up data are needed to assess the long-term safety and durability of the device.Abstract O-052 Table 1Baseline descriptive statistics Number of patients n=61 Gender Male 11 (18%) Female 50 (82%) Age (Years: median; IQR) 58 (51 – 68) Multiple Intracranial Aneurysms 21 (34.4%) Family history of aneurysms 9 (14.8%) Smoking History Never smokers 26 (42.6%) Past smokers 13 (21.3...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Salem, M., Kvint, S., Hendrix, P., Al Saiegh, F., Gajjar, A., Goren, O., Gross, B., Jabbour, P., Lang, M., Schirmer, C., Tjoumakaris, S., Griessenauer, C., Burkhardt, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

E-025 Aspiration thrombectomy of acute ischemic stroke patients with intracranial atherosclerotic disease or tandem lesion
ConclusionAspiration thrombectomy was effective in restoring blood flow and resulting in good 90-day functional outcome in AIS patients with anterior circulation tandem lesion, and the 90-day mortality rate in these patients was low. No significant difference in outcomes was detected between patients with a stent and patients without a stent.Disclosures O. Zaidat: 1; C; Genentech, Medtronic Neurovascular, Stryker. 2; C; Codman, Medtronic Neurovascular, National Institutes of Health StrokeNet, Penumbra, Stryker. J. Fifi: 1; C; Microvention, Penumbra, Stryker. 2; C; Microvention, Stryker. 4; C; Imperative Care. A. Hassan: 2;...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Zaidat, O., Fifi, J., Hassan, A. Tags: Electronic poster abstracts Source Type: research

Submaximal angioplasty for symptomatic intracranial atherosclerosis: a prospective Phase I study.
CONCLUSIONS This study demonstrates the safety of the submaximal angioplasty technique, with no permanent periprocedural complications in 24 treated patients. PMID: 26745485 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 8, 2016 Category: Neurosurgery Authors: Dumont TM, Sonig A, Mokin M, Eller JL, Sorkin GC, Snyder KV, Nelson Hopkins L, Levy EI, Siddiqui AH Tags: J Neurosurg Source Type: research

Insufficient platelet inhibition and thromboembolic complications in patients with intracranial aneurysms after stent placement.
CONCLUSIONS The ADP inhibition percentage is related to thromboembolic complications after stent placement for intracranial aneurysms. The increase of the ADP inhibition may decrease the risk of thromboembolic complications. PMID: 26587657 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 20, 2015 Category: Neurosurgery Authors: Yang H, Li Y, Jiang Y Tags: J Neurosurg Source Type: research

The detrimental clinical impact of severe angiographic vasospasm may be diminished by maximal medical therapy and intensive endovascular treatment
Conclusions An intensive endovascular approach of TBA and/or intra-arterial verapamil in combination with induced hypertension for severe aVSP may result in comparable clinical outcomes to those without vasospasm.
Source: Journal of NeuroInterventional Surgery - November 13, 2015 Category: Neurosurgery Authors: Mortimer, A. M., Steinfort, B., Faulder, K., Bradford, C., Finfer, S., Assaad, N., Harrington, T. Tags: Ischemic stroke Source Type: research

E-029 symptomatic hemodynamic depression occurring before balloon inflation during carotid angioplasty/stenting
ConclusionDuring CAS, hemodynamic depression is caused by the stretch-induced stimulation of the carotid sinus baroreceptors located in the adventitial walls of the carotid bulb. This baroreceptor activation caused by balloon dilatation and stent deployment causes increased afferent signals to the caudal medulla by way of the carotid sinus and glossopharyngeal nerves. The medulla subsequently responds by increasing parasympathetic impulses and decreasing sympathetic vascular tone, which results in bradycardia and hypotension. Reported incidences of HD as well as individual hemodynamic parameters following CAS procedures va...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Lee, J. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-073 safety and efficacy of flow reversal in carotid angioplasty and stenting using mo. ma device
ConclusionFlow reversal using MO. MA device is a safe and effective tool in preventing distal embolization during carotid stenting.DisclosuresR. Bo: None. A. Tiwari: None. K. Arcot: None. H. Dababneh: None. J. Farkas: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Bo, R., Tiwari, A., Arcot, K., Dababneh, H., Farkas, J. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Is the 'liberation procedure' for multiple sclerosis really liberating?
Multiple sclerosis (MS) is an inflammatory disease, which is immune-mediated, and responds to immune-modulating therapies. However, it is uncertain what antigen, or antigens, trigger the immune system to attack the central nervous system's (CNS's) myelin. Could it be iron? The predominantly venotopic location of MS lesions in the CNS has recently been postulated to be a consequence of congenital stenosis of the internal jugular or azygous veins, causing venous congestion and hypertension, and local transmural extravasation of erythrocytes into the white matter. The erythrocytes subsequently degrade, but the residual iron r...
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 5, 2014 Category: Neurosurgery Authors: Hankey, G. J., Sandercock, P., Cantisani, T. A., Celani, M. G. Tags: Immunology (including allergy), Multiple sclerosis, Stroke, Hypertension Editorial commentaries Source Type: research

Low-dose intravenous heparin infusion in patients with aneurysmal subarachnoid hemorrhage: a preliminary assessment.
Conclusions In patients with Fisher Grade 3 aSAH whose aneurysm is secured, postprocedure use of a low-dose intravenous heparin infusion may be safe and beneficial. PMID: 24032706 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - September 13, 2013 Category: Neurosurgery Authors: Simard JM, Aldrich EF, Schreibman D, James RF, Polifka A, Beaty N Tags: J Neurosurg Source Type: research