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Impaired perfusion modifies the relationship between blood pressure and stroke risk in major cerebral artery disease
Conclusions Impaired perfusion modified the relationship between blood pressure and stroke risk, although this study had limitations including the retrospective analysis, the potentially biased sample, the small number of critical events and the fact that BP was measured only as a snapshot in clinic.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Yamauchi, H., Higashi, T., Kagawa, S., Kishibe, Y., Takahashi, M. Tags: Open access, Stroke, Hypertension, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Enhancing cerebral perfusion with external counterpulsation after ischaemic stroke: how long does it last?
Conclusions Blood pressure elevation persists throughout ECP treatment, which consists of 35 sessions. However, cerebral blood flow augmentation may last at least 3 weeks and then appears to return to baseline 1 month after acute stroke onset.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 13, 2016 Category: Neurosurgery Authors: Xiong, L., Lin, W., Han, J., Chen, X., Leung, T., Soo, Y., Wong, K. S. Tags: Stroke, Hypertension Cerebrovascular disease Source Type: research

A perfusion territory shift attributable solely to the secondary collaterals in moyamoya patients: a potential risk factor for preoperative hemorrhagic stroke revealed by t-ASL and 3D-TOF-MRA.
CONCLUSIONS: t-ASL could reveal comprehensive MMD cerebral blood perfusion and the vivid perfusion territory shifts fed by the unilateral ICA and ECA and bilateral VAs in a noninvasive, straightforward, nonradioactive, and nonenhanced manner. 3D-TOF-MRA could subdivide t-ASL perfusion territory shifts according to their shunt arteries. A perfusion territory shift attributable to the secondary collaterals is a potential independent risk factor for preoperative hemorrhage in MMD patients. A perfusion territory shift fed by the primary collaterals may not have a strong effect on preoperative hemorrhage in MMD patients. These ...
Source: Journal of Neurosurgery - August 8, 2019 Category: Neurosurgery Authors: Gao XY, Li Q, Li JR, Zhou Q, Qu JX, Yao ZW Tags: J Neurosurg Source Type: research

E-073 safety and efficacy of flow reversal in carotid angioplasty and stenting using mo. ma device
ConclusionFlow reversal using MO. MA device is a safe and effective tool in preventing distal embolization during carotid stenting.DisclosuresR. Bo: None. A. Tiwari: None. K. Arcot: None. H. Dababneh: None. J. Farkas: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Bo, R., Tiwari, A., Arcot, K., Dababneh, H., Farkas, J. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Evidence for Cerebral Hemodynamic Measurement-based Therapy in Symptomatic Major Cerebral Artery Disease.
Authors: Yamauchi H Abstract In patients with atherosclerotic internal carotid artery or middle cerebral artery occlusive disease, chronic reduction in cerebral perfusion pressure (chronic hemodynamic compromise) increases the risk of ischemic stroke and can be detected by directly measuring hemodynamic parameters. However, strategies for selecting treatments based on hemodynamic measurements have not been clearly established. Bypass surgery has been proven to improve hemodynamic compromise. However, the benefit of bypass surgery for reducing the stroke risk in patients with hemodynamic compromise is controversial....
Source: Neurologia Medico-Chirurgica - June 5, 2015 Category: Neurosurgery Tags: Neurol Med Chir (Tokyo) Source Type: research

P-016 role of balloon guiding catheter in mechanical thrombectomy using stentretrivers subgroup analysis of swift prime
ConclusionBGC use in the SWIFT PRIME cohort of patients treated with rTPA and mechanical thrombectomy with Solitaire demonstrated significantly lower infarct size and higher reperfusion rates at 27 h. Overall procedure times were shorter for BGC group. These findings suggest that there is likely benefit from use of BGC when treating AIS with mechanical thrombectomy; however, randomized trials are required to confirm this finding.Abstract P-016 Table 1Distribution of variables among BGC and no BGC group Characteristic No BGC BGC Total p-value Number394887Age (years)61.8 ± 13.566.8 ± 11.764.6 ± 12....
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Pereira, V., Siddiqui, A., Jovin, T., Yavagal, D., Levy, E., Bonafe, A., Cognard, C., Jansen, O., Nogueira, R., Jahan, R., Slater, L., Coutinho, J., Saver, J., Goyal, M. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

O-013 Hypertension Decreases the Number and Duration of Collateral Openings during Middle Cerebral Artery Occlusion (MCAO) and Impairs Reperfusion
ConclusionsThese results demonstrate that collateral flow during ischemia, and reperfusion, was impaired in hypertension likely due to vasoconstriction of LMAs. Understanding the function of pial collaterals under conditions such as hypertension, that is associated with little penumbral tissue, may provide targeted therapies to prevent collateral failure and extend the time window for treatment in these patients.DisclosuresM. Cipolla: 1; C; NIH grants. J. Sweet: None. K. Chan: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Cipolla, M., Sweet, J., Chan, K. Tags: Oral abstracts Source Type: research

Postoperative hemorrhage during the acute phase after direct or combined revascularization for moyamoya disease: risk factors, prognosis, and literature review.
CONCLUSIONS: Preoperative hypertension, CTP stage > III, and posterior circulation involvement are independent risk factors for postoperative ICH after direct or combined revascularization for MMD. After appropriate perioperative management, postoperative ICH has no significant correlations with the postoperative short-term and long-term neurofunctional status. PMID: 31628285 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 17, 2019 Category: Neurosurgery Authors: Chen Y, Ma L, Lu J, Chen X, Ye X, Zhang D, Zhang Y, Wang R, Zhao Y Tags: J Neurosurg Source Type: research

E-088 Visualization of the anterior temporal artery as a predictor of outcome after mechanical thrombectomy
ConclusionThough the presence of the anterior temporal artery in patients undergoing recanalization for MCA occlusion did not reach statistical significance for predicting independent outcomes, there was a strong trend for improved outcomes. Particularly for institutions without CTP capability or when CTP data is not-reliable, this association with ATA visualization should be further investigated as a predictor for good outcome after successful mechanical thrombectomy.Disclosures J. Parish: None. W. Stetler: None. D. Strong: None. T. Prasad: None. J. Rhoten: None. R. Karamchandani: None. J. Clemente: None. G. Defilipp: Non...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Parish, J., Stetler, W., Strong, D., Prasad, T., Rhoten, J., Karamchandani, R., Clemente, J., Defilipp, G., Hines, A., Bernard, J., Asimos, A. Tags: Electronic poster abstracts Source Type: research