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A Nomogram for Predicting Patent Foramen Ovale-Related Stroke Recurrence
ConclusionsNomogram 1, based on Hcy, hsCRP, and ALB levels, provided a more clinically realistic prognostic prediction for patients with PFO-related stroke. This model could help patients with PFO-related stroke to facilitate personalized prognostic evaluations.
Source: Frontiers in Neurology - June 9, 2022 Category: Neurology Source Type: research

Stroke territory and atherosclerosis in ischemic stroke patients with a history of migraine with aura
DiscussionCryptogenic and cerebellar stroke and fewer vascular risk factors and clinical atherosclerosis seem to characterize stroke patients with MA.
Source: Frontiers in Neurology - February 27, 2023 Category: Neurology Source Type: research

Structural Equation Model (SEM) of Stroke Mortality in Spanish Inpatient Hospital Settings: The Role of Individual and Contextual Factors
Conclusion. Contextual variables, and specifically the availability of stroke units, make a positive impact on individual variables that affect prognosis and mortality in ischemic stroke. Moreover, the determination of this impact is feasible through the use of structural equation methodology. We analyze the methodological and clinical implications of this type of study for hospital policies. Key words: Stroke; mortality; structural equation model; predictive model
Source: Frontiers in Neurology - May 16, 2019 Category: Neurology Source Type: research

Smoking Does Not Alter Treatment Effect of Intravenous Thrombolysis in Mild to Moderate Acute Ischemic Stroke —A Dutch String-of-Pearls Institute (PSI) Stroke Study
Conclusions: In patients with mild to moderate AIS admitted within 12 h of symptom onset, smoking did not modify treatment effect of thrombolysis.
Source: Frontiers in Neurology - July 30, 2020 Category: Neurology Source Type: research

Bilateral Vertebral Artery Hypoplasia and Fetal-Type Variants of the Posterior Cerebral Artery in Acute Ischemic Stroke
Conclusion: Patients with bilateral vertebral hypoplasia displayed a unique collateral supply, special stroke pattern, and younger stroke onset. Early recognition and stroke prevention should be considered critical in clinical practice.
Source: Frontiers in Neurology - April 8, 2021 Category: Neurology Source Type: research

Stroke Related Knowledge, Prevention Practices and Associated Factors Among Hypertensive Patients at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2021
ConclusionThe proportion of participants with good-related knowledge and prevention practice is relatively good.
Source: Frontiers in Neurology - April 19, 2022 Category: Neurology Source Type: research

Higher comorbidity burden is associated with lower self-reported quality of life after stroke
ConclusionIn patients with AIS, high comorbidity burden and polypharmacy are frequent. Comorbidity burden at admission is independently associated with worse self-reported physical and mental health three months after stroke.
Source: Frontiers in Neurology - November 10, 2022 Category: Neurology Source Type: research

Outcomes associated with antithrombotic strategies in heart failure with reduced ejection fraction and sinus rhythm following acute ischemic stroke
ConclusionIn HFrEF patients with an acute stroke, there was no difference in outcomes of antithrombotic strategies. While this study was limited by non-randomized treatment allocation, the results support future trials of stroke patients with HFrEF which may randomize patients to anticoagulation or antiplatelet.
Source: Frontiers in Neurology - December 15, 2022 Category: Neurology Source Type: research

Risk factor identification and prediction models for prolonged length of stay in hospital after acute ischemic stroke using artificial neural networks
ConclusionThe artificial neural network model achieved adequate discriminative power for predicting prolonged length of stay after acute ischemic stroke and identified crucial factors associated with a prolonged hospital stay. The proposed model can assist in clinically assessing the risk of prolonged hospitalization, informing decision-making, and developing individualized medical care plans for patients with acute ischemic stroke.
Source: Frontiers in Neurology - February 9, 2023 Category: Neurology Source Type: research

Delivering acute stroke care in a middle-income country. The Mexican model: “ResISSSTE Cerebro”
ConclusionWith the implementation of a modified hub-and-spoke model, this study shows that delivery of AS care in low- and middle-income countries is feasible and achieves good clinical outcomes.
Source: Frontiers in Neurology - February 22, 2023 Category: Neurology Source Type: research

Angiotensin-converting enzyme gene insertion/deletion polymorphism and risk of ischemic stroke complication among patients with hypertension in the Ethiopian population
ConclusionThere is a significant correlation between the ACE gene I/D polymorphism and the development of ischemic stroke in patients with a history of hypertension in the Ethiopian population.
Source: Frontiers in Neurology - March 22, 2023 Category: Neurology Source Type: research

Distance Neurological Supervision Using Telestroke Does Not Increase Door-to-Needle Time in Acute Ischemic Stroke Management: The Experience of Two Regional Stroke Units
Conclusions: On-site systematic evaluation by a neurologist did not appear to influence door-to-needle time OWH, suggesting distance supervision may be time-efficient in thrombolysis. This supports existing prospective studies in hyperacute telestroke management. The relevance lies in optimizing resource use considering the increasing demand for emergency neurological management.
Source: Frontiers in Neurology - March 19, 2021 Category: Neurology Source Type: research

Functional outcome prediction of ischemic stroke patients with atrial fibrillation accepting post-acute care training
ConclusionIn the current study, nearly half of the enrolled patients showed favorable functional recovery. The outcome assessments seem to correlate well with NIHSS and Barthel Index scores, rather than mRS. The anxiety/depression and usual activities domains of the EQ-5D results are associated with and have a great impact after the patients undertake the PAC rehabilitative strategy. Moreover, the variables obtained through carotid duplex and plaque index might also play a significant role in determining the patient's functional outcome.
Source: Frontiers in Neurology - September 23, 2022 Category: Neurology Source Type: research

Differences in clinical and biological factors between patients with PFO-related stroke and patients with PFO and no cerebral vascular events
We present a study concerning clinical, demographic, and laboratory factors associated with stroke and transient ischemic attack in patients with patent foramen ovale (PFO), as well as comparing PFO-patients with and without cerebrovascular ischemic events (CVEs).Patients and methodsConsecutive patients with PFO-associated CVEs were included in the study; control group was selected from patients with a PFO and no history of stroke. All participants underwent peripheral routine blood analyses, as well as, on treating physician's recommendations, screening for thrombophilia.ResultsNinety-five patients with CVEs and 41 contro...
Source: Frontiers in Neurology - March 14, 2023 Category: Neurology Source Type: research

Effect of Hyperhomocysteinemia on Clinical Outcome and Hemorrhagic Transformation After Thrombolysis in Ischemic Stroke Patients
Conclusion: We found that Hhcy was an independent risk factor for poor outcome, but not an independent risk factor for HT after thrombolysis in ischemic stroke patients. In addition, there was no significant interaction of Hhcy and hypertension on the clinical outcome or HT after thrombolysis.
Source: Frontiers in Neurology - June 3, 2019 Category: Neurology Source Type: research

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