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Specialty: Pathology
Condition: Translocation
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Total 591 results found since Jan 2013.
The incidence of translocation t(11;14) among patients with multiple myeloma in a single clinic
CONCLUSIONS: This report suggests that some patients may need to retest for this genetic aberration due to the possibility of false negatives and the potential benefit of identifying the t(11;14) marker for patients who may be candidates for a highly effective targeted therapy consisting of the BCL-2 inhibitor venetoclax.PMID:37611113 | DOI:10.1093/ajcp/aqad103
Source: American Journal of Clinical Pathology - August 23, 2023 Category: Pathology Authors: Scott Jew Marissa-Skye Goldwater Sean Bujarski Bernard Regidor Marsiye Emamy-Sadr Regina Swift Benjamin Eades Jonathan Said James R Berenson Source Type: research
Cellular localization of FOXO3 determines its role in cataractogenesis
In conclusion, we demonstrated the correlation between the localization of FOXO3 and its function in cataract formation. We also determined that H2 protects HLECs from injury by leading FOXO3 mitochondrial translocation via MAPK1 activation. Mitochondrial FOXO3 can increase mtDNA transcription, stabilize mitochondrial function in HLECs.PMID:37517685 | DOI:10.1016/j.ajpath.2023.06.016
Source: The American Journal of Pathology - July 30, 2023 Category: Pathology Authors: Xiaoqi Li Yingxin Qu Qinghua Yang Runpu Li Yumei Diao Junyi Wang Lingling Wu Chuyue Zhang Shaoyuan Cui Limin Qin Deyi Zhuo Huiyi Wang Liqiang Wang Yifei Huang Source Type: research
