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Plasma Neurofilament Light Chain Is Associated with Poor Functional Outcome and Mortality Rate After Spontaneous Subarachnoid Hemorrhage
AbstractThe initial clinical status after subarachnoid hemorrhage (SAH) is an important outcome predictor, but the mechanisms behind the early brain injury (EBI) remains incompletely understood. Elevated neurofilament levels in the cerebrospinal fluid at protracted stages after SAH are associated with poor outcome, but the potential association between plasma neurofilament (pNfL) levels during EBI, disease severity on admission, and poor outcome remains unaddressed. Plasma NfL (pNfL) was measured by single molecule array in 44 SAH patients on admission and 24  h after ictus, as well as in 44 controls. Disease severity on ...
Source: Translational Stroke Research - December 4, 2019 Category: Neurology Source Type: research

Stereotactic Catheter Ventriculocisternostomy for Clearance of Subarachnoid Hemorrhage Clinical Sciences
Conclusions—STX-VCS was feasible and safe in patients with severe aneurysmal subarachnoid hemorrhage. Initial results indicate that DCI and mortality can be reduced, and neurological outcome may be improved with this method.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Roland Roelz, Volker A. Coenen, Christian Scheiwe, Wolf-Dirk Niesen, Karl Egger, Istvan Csok, Rainer Kraeutle, Ramazan Jabbarli, Horst Urbach, Peter C. Reinacher Tags: Cerebral Aneurysm, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Elevated Red Cell Distribution Width is Associated with Cerebral Infarction in Aneurysmal Subarachnoid Hemorrhage
ConclusionsRDW elevation is associated with cerebral infarction and poor outcome after aSAH. Further evaluation of this association is warranted as it may shed light on mechanistic relations between anemia, inflammation, and thrombosis after aSAH.
Source: Neurocritical Care - August 15, 2016 Category: Neurology Source Type: research