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Teaching NeuroImages: HIV-associated cerebral vasculopathy with multiple nodular aneurysms
HIV-associated cerebral vasculopathy with multiple aneurysms has been widely reported in children1 and has to be considered in HIV-infected patients with high CSF viral load, but only few cases in adults have been published so far. Nodular and fusiform aneurysms (figure, A–D) are a typical imaging finding2 that may lead to suspicion of an autoimmune etiology by mimicking polyarteritis nodosa. These aneurysms might carry clinical significance with regard to the risk of subarachnoid or intracerebral hemorrhage, or causing infarction through formation of emboli. Highly active antiretroviral therapy leads to remission of...
Source: Neurology - April 3, 2017 Category: Neurology Authors: Seiler, A., You, S.-J., Wagner, M., Klein, J. C. Tags: Stroke in young adults, All Imaging, Vasculitis, HIV, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Stroke in HIV-infected African Americans: a retrospective cohort study
Abstract The risk of having a first stroke is nearly twice as high among African Americans compared to Caucasians. HIV/AIDS is an independent risk factor for stroke. Our study aimed to report the risk factors and short-term clinical outcomes of African Americans with HIV infection and new-onset stroke admitted at the Johns Hopkins Hospitals (2000–2012). Multivariate linear regression was used to examine the association between potential predictors and odds of an unfavorable outcome, defined as a higher modified Rankin Scale (mRS) score on hospital discharge. African Americans comprised 105/125 (84 %) of HIV-inf...
Source: Journal of NeuroVirology - July 9, 2015 Category: Neurology Source Type: research