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Cerebrovascular Manifestations of SARS-CoV-2: A Comprehensive Review
AbstractPurpose of reviewThe risks of cerebrovascular manifestations due to SARS-CoV-2 infection are significantly increased within the first 6 months of the infection. Our work aims to give an update on current clinical aspects of diagnosis and treatment of cerebrovascular manifestations during acute and long-term SARS-CoV-2 infection.Recent findingsThe incidence of acute ischemic stroke and haemorrhagic stroke during acute SARS-CoV-2 patients is estimated at 0.9 to 4.6% and 0.5 –0.9%, respectively, and were associated with increased mortality. The majority presented with hemiparesis, dysarthria, sensory deficits, and a...
Source: Current Treatment Options in Neurology - March 4, 2023 Category: Neurology Source Type: research

Observational Study of Patients Hospitalized With Neurologic Events After SARS-CoV-2 Vaccination, December 2020-June 2021
Discussion All cases in this study were determined to have at least 1 risk factor and/or known etiology accounting for their neurologic syndromes. Our comprehensive clinical review of these cases supports the safety of mRNA COVID-19 vaccines.
Source: Neurology Clinical Practice - May 25, 2023 Category: Neurology Authors: Kim, C. Y., McNeill, E. N., Young, C., King, F., Clague, M., Caldwell, M., Boruah, A., Zucker, J., Thakur, K. T. Tags: Autoimmune diseases, Post-infectious, Inclusion, Diversity, Equity, Anti-racism, and Social Justice (IDEAS), COVID-19 Research Article Source Type: research

Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description
We describe pathological and radiological data consistent with thrombotic microangiopathy caused by endotheliopathy with a haemorrhagic predisposition.
Source: Brain - July 9, 2020 Category: Neurology Source Type: research

Intracranial hemorrhage in hospitalized SARS-CoV-2 Patients: A Case Series
The SARS-CoV-2 virus causing Coronavirus Disease 2019 (COVID-19) is a global pandemic with almost 30 million confirmed worldwide cases. Prothrombotic complications arising from those affected with severe symptoms have been reported in various medical journals. Currently, clinical trials are underway to address the questions regarding anticoagulation dosing strategies to prevent thrombosis for these critically ill patients. However, given the increasing use of therapeutic anticoagulation in patients admitted with COVID-19 to curtail this prothrombotic state, our institution has witnessed six cases of devastating intracrania...
Source: Journal of Stroke and Cerebrovascular Diseases - October 31, 2020 Category: Neurology Authors: Fady Mousa-Ibrahim, Stephanie Berg, Oluwatobi Odetola, Michael Teitcher, Sean Ruland Source Type: research