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Source: Journal of the Neurological Sciences
Condition: Hemorrhagic Stroke

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Total 94 results found since Jan 2013.

Repeated intravenous thrombolysis after recurrent stroke. A case series and review of the literature
Conclusions: IV re-thrombolysis may be safe and effective when recurrent stroke occurs after a period of complete neurologic regression lasting at least 24h or minor disability (mRS score ≤2) lasting at least 3months since the previous stroke.Highlights:
Source: Journal of the Neurological Sciences - July 25, 2014 Category: Neurology Authors: Manuel Cappellari, Giuseppe Moretto, Paolo Bovi Tags: Original Articles Source Type: research

Associations between stroke type, stroke severity, and pre-stroke osteoporosis with the risk of post-stroke fracture: A nationwide population-based study
BackgroundRecognizing the post-stroke fracture risk factors is crucial for targeted intervention and primary fracture prevention. We aimed to investigate whether stroke types, stroke severity, and pre-stroke osteoporosis are associated with post-stroke fracture.MethodsIn a nationwide cohort, we identified previously fracture-free patients who suffered from first-ever stroke, either acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH), between 2003 and 2015. Information regarding stroke severity, osteoporosis, comorbidity, and medication information was collected.
Source: Journal of the Neurological Sciences - May 27, 2021 Category: Neurology Authors: Hung-Ping Wang, Sheng-Feng Sung, Hsin-Yi Yang, Wan-Ting Huang, Cheng-Yang Hsieh Source Type: research

The efficacy and safety of aspirin plus dipyridamole versus aspirin in secondary prevention following TIA or stroke: A meta-analysis of randomized controlled trials
Conclusions: Aspirin plus dipyridamole combination therapy was beneficial in reducing the recurrence of stroke, and did not increase the bleeding event. Hence, aspirin plus dipyridamole combination therapy is effective and safe for the secondary prevention of stroke.
Source: Journal of the Neurological Sciences - July 19, 2013 Category: Neurology Authors: Xia Li, Guoyu Zhou, Xueying Zhou, Shengnian Zhou Tags: Original Articles Source Type: research

Predicting symptomatic intracerebral hemorrhage after intravenous thrombolysis: Stroke territory as a potential pitfall
Conclusions: The risk of SICH after intravenous thrombolysis in patients with posterior circulation stroke was low enough to render the SITS SICH risk score or other similar prediction models unnecessary. Awareness of stroke territory might help clinicians judiciously use the risk assessment models.
Source: Journal of the Neurological Sciences - September 19, 2013 Category: Neurology Authors: Sheng-Feng Sung, Chih-Hung Chen, Yu-Wei Chen, Mei-Chiun Tseng, Hsiu-Chu Shen, Huey-Juan Lin Tags: Original Articles Source Type: research

Experience of pediatric stroke from a tertiary medical center in North India
Conclusion: AIS is more common than ICH in this study and 8.9% patients died. Infection is the most common cause of pediatric stroke in Northern India which is amenable to therapy and is preventable.
Source: Journal of the Neurological Sciences - December 26, 2012 Category: Neurology Authors: Jayantee Kalita, Gourav Goyal, Usha Kant Misra Tags: Original Articles Source Type: research

The Sub-Saharan Africa Conference on Stroke (SSACS): An idea whose time has come
Stroke is a leading cause of global morbidity and mortality. Sub-Saharan Africa (SSA), where an unprecedented rise in stroke burden is currently raging, has the highest age-standardized stroke incidence, stroke prevalence, and stroke mortality rates. This is in sharp contrast to the relative decline in stroke incidence in high-income countries over the past four decades through better awareness and control of vascular risk factors. Compared to other groups, Africans tend to have a higher risk of stroke, higher percentage of the hemorrhagic type and much poorer outcomes.
Source: Journal of the Neurological Sciences - March 28, 2019 Category: Neurology Authors: Mayowa Owolabi, Fred Stephen Sarfo, Rufus Akinyemi, Mehari Gebreyohanns, Bruce Ovbiagele Tags: Review Article Source Type: research

Early initiation of new oral anticoagulants in acute stroke and TIA patients with nonvalvular atrial fibrillation
Conclusions: The NOAC may be safe in acute stroke or TIA patients with NVAF. A large, prospective study is needed to confirm this.
Source: Journal of the Neurological Sciences - June 5, 2013 Category: Neurology Authors: Kensaku Shibazaki, Kazumi Kimura, Junya Aoki, Naoki Saji, Kenichiro Sakai Tags: Original Articles Source Type: research

Stroke warning syndrome: 18 new cases
Conclusion: SWS is an under-recognized syndrome. Intravenous rt-PA treatment seems to have lower efficacy than in other subtypes of strokes, but none of the patients with SWS undergoing treatment presented haemorrhagic transformation or other complications.
Source: Journal of the Neurological Sciences - June 13, 2013 Category: Neurology Authors: Rossana Tassi, Alfonso Cerase, Maurizio Acampa, Paolo D’Andrea, Francesca Guideri, Giuseppe Lo Giudice, Giovanna Marotta, Sandra Bracco, Giuseppe Martini Tags: Short Communictions Source Type: research

Reservations against new oral anticoagulants after stroke and cerebral bleeding
Abstract: Dabigatran, rivaroxaban, and apixaban are the new oral anticoagulants (NOAC) which have been investigated in patients with atrial fibrillation (AF) for primary and secondary prevention of stroke and thromboembolism. In these trials NOAC had a similar efficacy and safety profile compared to traditional vitamin-K-antagonists such as warfarin. We advise caution in the use of NOAC in patients with stroke or cerebral hemorrhage because of the following reasons:1) Patients with cerebral bleeding were excluded from the trials. 2) Stroke within 14days and severe stroke within 6months before screening were exclusion crite...
Source: Journal of the Neurological Sciences - April 29, 2013 Category: Neurology Authors: Claudia Stöllberger, Josef Finsterer Tags: Opinion Source Type: research

Intravenous thrombolysis with rt-PA for acute ischemic stroke within 24h of a transient ischemic attack
Conclusion: TIA within 24h prior to ischemic stroke can portend severe intracerebral bleeding in patients qualified to iv-thrombolysis with the use of rt-PA.
Source: Journal of the Neurological Sciences - March 13, 2014 Category: Neurology Authors: Piotr Sobolewski, Waldemar Brola, Małgorzata Wiszniewska, Wiktor Szczuchniak, Małgorzata Fudala, Mariusz Domagalski, Monika Śledzińska-Dźwigał Tags: Original Articles Source Type: research

Increased circulating endothelial progenitor cells in patients with haemorrhagic and ischaemic stroke: The role of Endothelin-1
Abstract: Ischaemic stroke induces endothelial progenitor cell (EPC) mobilisation from bone marrow into peripheral blood. Circulating EPCs play an important role in post-injury regeneration of vasculature, whereas endothelial cells (ECs) have been shown to reflect endothelial damage and may be responsible for increased Endothelin-1 (ET-1) expression. We investigated herein the association between numbers of circulating ECs and EPCs, the levels of soluble factors regulating their migration and function, and the clinical outcome in patients with haemorrhagic (HS) or ischaemic stroke (IS). Sixteen patients with HS and eightee...
Source: Journal of the Neurological Sciences - January 7, 2013 Category: Neurology Authors: E. Paczkowska, M. Gołąb-Janowska, A. Bajer-Czajkowska, A. Machalińska, P. Ustianowski, M. Rybicka, P. Kłos, V. Dziedziejko, K. Safranow, P. Nowacki, B. Machaliński Tags: Original Articles Source Type: research

Development of a short form of Stroke-Specific Quality of Life Scale for patients after aneurysmal subarachnoid hemorrhage
Conclusions: The 12-item Chinese version of SSQOL-a has a satisfactory internal consistency and criterion validity for SAH patients at 12month assessments.
Source: Journal of the Neurological Sciences - October 11, 2013 Category: Neurology Authors: George Kwok Chu Wong, Sandy Wai Lam, Karine Ngai, Adrian Wong, Wai Sang Poon, Vincent Mok Tags: Original Articles Source Type: research

Reply to effect of CYP2C19*2 and *3 on clinical outcome in ischemic stroke patients treated with Clopidogrel
We read with great interest the recent publication of Wang et al. [1] evaluating the relationship between CYP2C19 genotypes with nonfatal ischemic stroke, myocardial infarction, or vascular death. The striking finding of this study was that the presence of CYP2C19 loss of function (LOF) alleles may increase the recurrent risk of ischemic events. The polymorphisms of CYP2C19 may be predictors of poor functional outcome of patients without stent and the effect may be weakened by time [1]. Similarly, the authors recently demonstrated that in patients with transient ischemic attack (TIA) or minor stroke who can be treated with...
Source: Journal of the Neurological Sciences - October 31, 2016 Category: Neurology Authors: Demetrios Moris, Chris Bakoyiannis, Georgios Karaolanis, Sotirios Georgopoulos Tags: Letter to the Editor Source Type: research

Association of hyperglycemia and computed tomographic perfusion deficits in patients who underwent endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion: A subgroup analysis of a randomized phase 3 trial (MR CLEAN)
Hyperglycemia is highly prevalent in patients with acute ischemic stroke and is associated with increased risk of symptomatic intracranial hemorrhage, larger infarct size and unfavorable outcome. Furthermore, glucose may modify the effect of endovascular treatment (EVT) in patients with ischemic stroke. Hyperglycemia might lead to accelerated conversion of penumbra into infarct core. However, it remains uncertain whether hyperglycemia on admission is associated with the size of penumbra or infarct core in acute ischemic stroke.
Source: Journal of the Neurological Sciences - June 30, 2022 Category: Neurology Authors: C.J.B.A. Kersten, A.A.M. Zandbergen, O.A. Berkhemer, J. Borst, M. Haalboom, Y.B.W.E.M. Roos, D.W.J. Dippel, R.J. van Oostenbrugge, A. van der Lugt, W.H. van Zwam, C.B. Majoie, H.M. den Hertog, on behalf of the MR CLEAN investigators Source Type: research