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Reduction in estimated glomerular filtration rate (eGFR) results in an increased risk of spontaneous hemorrhagic transformation in patients with large-artery atherosclerosis stroke.
In conclusion, reduced eGFR was significantly associated with increased risk of spontaneous HT in all ischemic stroke patients, and in large artery atherosclerosis, not in cardio-embolism stroke. Reduced eGFR did not increase the risk of symptomatic HT. PMID: 26503023 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - October 27, 2015 Category: Neurology Authors: Liu B, Wang D, Hao Z, Li D, Zhang J, Liu J, Liu M Tags: Curr Neurovasc Res Source Type: research

Iron Overload is Associated with Perihematoma Edema Growth following Intracerebral Hemorrhage that May Contribute to in-Hospital Mortality and Long-Term Functional Outcome.
Abstract Iron overload may contribute to brain damage that involves delayed brain atrophy, edema, and neuronal cell death as well as unfavorable outcome following ischemic stroke and intracerebral hemorrhage (ICH).This prospective study wasperformed to determine the association of serum ferritin level, an iron storage protein, with perihematoma edema (PHE) growth as well as in-hospital mortality and long-term clinical outcome of patients with ICH.Data was collected prospectively from patients with ICH between February 2011 and April 2012. Demographicand clinical datawere recorded and serum ferritin was measured on...
Source: Current Neurovascular Research - May 30, 2014 Category: Neurology Authors: Bakhshayesh B, Hosseininezhad M, Nazanin S, Saadat SN, Ansar MM, Ramezani H, Saadat SM Tags: Curr Neurovasc Res Source Type: research