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Reduction in estimated glomerular filtration rate (eGFR) results in an increased risk of spontaneous hemorrhagic transformation in patients with large-artery atherosclerosis stroke.
In conclusion, reduced eGFR was significantly associated with increased risk of spontaneous HT in all ischemic stroke patients, and in large artery atherosclerosis, not in cardio-embolism stroke. Reduced eGFR did not increase the risk of symptomatic HT. PMID: 26503023 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - October 27, 2015 Category: Neurology Authors: Liu B, Wang D, Hao Z, Li D, Zhang J, Liu J, Liu M Tags: Curr Neurovasc Res Source Type: research

Increased Neutrophil-to-lymphocyte Ratios are Associated with Greater Risk of Hemorrhagic Transformation in Patients with Acute Ischemic Stroke.
CONCLUSIONS: Higher level of NLR is associated with greater risk of hemorrhagic transformation in patients with acute ischemic stroke, especially in cardio-embolic stroke. Moreover, the results suggest that therapeutic interventions that may increase the risk of bleeding should be undertaken carefully in the management of AIS patients with higher NLR. PMID: 30514190 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - December 4, 2018 Category: Neurology Authors: Song Q, Li Y, Wang Y, Wei C, Liu J, Liu M Tags: Curr Neurovasc Res Source Type: research

Association between coagulation function and spontaneous hemorrhagic transformation in acute ischemic stroke.
CONCLUSION: Not the whole process of coagulation function is associated with spontaneous HT. Prolonged TT, which may indicate an extension of the last step of the coagulation process, is independently and inversely associated with spontaneous HT in patients with acute ischemic stroke. PMID: 32407276 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - May 13, 2020 Category: Neurology Authors: Ye C, Wang Y, Song Q, Liu J, Wei C, Liu M Tags: Curr Neurovasc Res Source Type: research

Prognostic parameters for symptomatic intracranial hemorrhage after intravenous thrombolysis in acute ischemic stroke in an Asian population.
Abstract Symptomatic intracranial hemorrhage (sICH) is a major complication after intravenous thrombolysis leading to severe disability and death. The incidence was higher in Asian than in westernized countries. Prognostic factors across ethnicities are presumably different. Studies in Asian populations are limited. Clinical data from January 2008 to September 2016 in one provincial and four regional hospitals in the northern part of Thailand were retrospectively reviewed. Patients were those with acute ischemic stroke, to whom recombinant tissue plasminogen activator (rt-PA) had been prescribed. They were classif...
Source: Current Neurovascular Research - March 27, 2017 Category: Neurology Authors: Lokeskrawee T, Muengtaweepongsa S, Patumanond J, Tiamkao S, Thamangraksat T, Phankhian P, Pleumpanupatand P, Sribussara P, Kitjavijit T, Supap A, Rattanaphibool W, Prisiri J Tags: Curr Neurovasc Res Source Type: research

The Association of the Spatial Location of Contrast Extravasation with Symptomatic Intracranial Hemorrhage after Endovascular Therapy in Acute Ischemic Stroke Patients
Conclusion The spatial location of CE on NCCT immediately after EVT was an independent and strong risk factor for sICH in acute ischemic stroke patients.PMID:37488759 | DOI:10.2174/1567202620666230721101413
Source: Current Neurovascular Research - July 25, 2023 Category: Neurology Authors: Chen Gong You Wang Jinxian Yuan Jie Zhang Shuyu Jiang Tao Xu Yangmei Chen Source Type: research

Iron Overload is Associated with Perihematoma Edema Growth following Intracerebral Hemorrhage that May Contribute to in-Hospital Mortality and Long-Term Functional Outcome.
Abstract Iron overload may contribute to brain damage that involves delayed brain atrophy, edema, and neuronal cell death as well as unfavorable outcome following ischemic stroke and intracerebral hemorrhage (ICH).This prospective study wasperformed to determine the association of serum ferritin level, an iron storage protein, with perihematoma edema (PHE) growth as well as in-hospital mortality and long-term clinical outcome of patients with ICH.Data was collected prospectively from patients with ICH between February 2011 and April 2012. Demographicand clinical datawere recorded and serum ferritin was measured on...
Source: Current Neurovascular Research - May 30, 2014 Category: Neurology Authors: Bakhshayesh B, Hosseininezhad M, Nazanin S, Saadat SN, Ansar MM, Ramezani H, Saadat SM Tags: Curr Neurovasc Res Source Type: research

U-Shaped Association Between Serum Uric Acid and Hemorrhagic Transformation After Thrombolysis
CONCLUSION: The data show the U-shaped relationship between serum UA levels and the risk of HT and sICH after intravenous thrombolysis.PMID:35796447 | DOI:10.2174/1567202619666220707093427
Source: Current Neurovascular Research - July 7, 2022 Category: Neurology Authors: Zicheng Cheng Zhenxiang Zhan Yaming Fu WenYuan Zhang Lingfan Xia Tong Xu Hongfang Chen Zhao Han Source Type: research

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