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Source: Stroke
Condition: Hemorrhagic Stroke
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Total 995 results found since Jan 2013.
Cerebrovascular Accidents During Mechanical Circulatory Support Clinical Sciences
Conclusions—Stroke is a major cause of morbidity and mortality in patients on LVAD support. Chronic obstructive pulmonary disease increases the risk of ischemic stroke, whereas dialysis may increase the risk of hemorrhagic stroke. Although any stroke increases mortality, post-LVAD hemorrhagic stroke was associated with higher mortality compared with ischemic stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Saef Izzy, Daniel B. Rubin, Firas S. Ahmed, Feras Akbik, Simone Renault, Katelyn W. Sylvester, Henrikas Vaitkevicius, Jennifer A. Smallwood, Michael M. Givertz, Steven K. Feske Tags: Heart Failure, Complications, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Evolution of a US County System for Acute Comprehensive Stroke Care Clinical Sciences
We examined relationships between stroke details, reperfusion therapies, hospital transfers, and their change over time.Methods—All patients from January 1, 2013, to December 31, 2015, for whom 911 was called within 7 hours of onset in whom Emergency Medical Services personnel suspected acute stroke were evaluated.Results—Among 6132 patients, 3924 (64%) had confirmed diagnosis of stroke (74% ischemic/26% hemorrhagic), yielding diagnostic precision of 64% in the field. Of the 2892 patients with acute ischemic stroke, acute reperfusion therapy was given to 29.2% (21.7% intravenous tPA [tissue-type plasminogen activator] ...
Source: Stroke - April 23, 2018 Category: Neurology Authors: Radoslav I. Raychev, Dana Stradling, Nirav Patel, Joey R. Gee, David A. Lombardi, Johnson L. Moon, David M. Brown, Mayank Pathak, Wengui Yu, Samuel J. Stratton, Steven C. Cramer Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research
Thalidomide Reduces Hemorrhage of Brain Arteriovenous Malformations in a Mouse Model Basic Sciences
Conclusions—Thalidomide and lenalidomide improve mural cell coverage of bAVM vessels and reduce bAVM hemorrhage, which is likely through upregulation of Pdgfb expression.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Wan Zhu, Wanqiu Chen, Dingquan Zou, Liang Wang, Chen Bao, Lei Zhan, Daniel Saw, Sen Wang, Ethan Winkler, Zhengxi Li, Meng Zhang, Fanxia Shen, Sonali Shaligram, Michael Lawton, Hua Su Tags: Angiogenesis, Animal Models of Human Disease, Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Beneficial Role of Neutrophils Through Function of Lactoferrin After Intracerebral Hemorrhage Basic Sciences
Conclusions—LTF delivered to the ICH-affected brain by infiltrating PMNs may assist in hematoma detoxification and represent a powerful potential target for the treatment of ICH.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Xiurong Zhao, Shun–Ming Ting, Guanghua Sun, Meaghan Roy–O’Reilly, Alexis S. Mobley, Jesus Bautista Garrido, Xueping Zheng, Lidiya Obertas, Joo Eun Jung, Marian Kruzel, Jaroslaw Aronowski Tags: Translational Studies Original Contributions Source Type: research
Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke Basic Sciences
Conclusions—This study demonstrated for the first time that in a large animal model novel NSC EVs significantly improved neural tissue preservation and functional levels post-MCAO, suggesting NSC EVs may be a paradigm changing stroke therapeutic.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Robin L. Webb, Erin E. Kaiser, Brian J. Jurgielewicz, Samantha Spellicy, Shelley L. Scoville, Tyler A. Thompson, Raymond L. Swetenburg, David C. Hess, Franklin D. West, Steven L. Stice Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies, Treatment, Ischemic Stroke Original Contributions Source Type: research
Unmet Needs and Challenges in Clinical Research of Intracerebral Hemorrhage Special Report
Source: Stroke - April 23, 2018 Category: Neurology Authors: The Hemorrhagic Stroke Academia Industry (HEADS) Roundtable Participants* Tags: Statements and Guidelines, Intracranial Hemorrhage Special Reports Source Type: research
Basic and Translational Research in Intracerebral Hemorrhage Special Report
Source: Stroke - April 23, 2018 Category: Neurology Authors: The Hemorrhagic Stroke Academia Industry (HEADS) Roundtable Participants* Tags: Animal Models of Human Disease, Basic Science Research, Intracranial Hemorrhage Special Reports Source Type: research
Risk Factors for and Clinical Consequences of Multiple Intracranial Aneurysms Clinical Sciences
Conclusions—Female sex, higher age, arterial hypertension, smoking, and familial IA are major risk factors for MIA. In addition, MIA patients are at risk for enhanced IA formation. Further studies are needed to evaluate rupture risk and the role of ethnicity, especially in the context of increased MIA identification with improved neurovascular imaging.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Ramazan Jabbarli, Thiemo Florin Dinger, Marvin Darkwah Oppong, Daniela Pierscianek, Philipp Dammann, Karsten H. Wrede, Klaus Kaier, Martin Kohrmann, Michael Forsting, Christoph Kleinschnitz, Ulrich Sure Tags: Risk Factors, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Aneurysm Original Contributions Source Type: research
Desirable Low-Density Lipoprotein Cholesterol Levels for Preventing Stroke Recurrence Clinical Sciences
Conclusions—The composite risk of stroke and transient ischemic attack reduced in the postrandomized LDL cholesterol level of 80 to 100 mg/dL after adjusting for statin usage.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00221104.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Naohisa Hosomi, Kazuo Kitagawa, Yoji Nagai, Yoko Nakagawa, Shiro Aoki, Tomohisa Nezu, Tatsuo Kagimura, Hirofumi Maruyama, Hideki Origasa, Kazuo Minematsu, Shinichiro Uchiyama, Masayasu Matsumoto Tags: Lipids and Cholesterol, Secondary Prevention, Treatment Original Contributions Source Type: research
Rescue Stenting for Failed Mechanical Thrombectomy in Acute Ischemic Stroke Clinical Sciences
Conclusions—RS was independently associated with good outcomes without increasing symptomatic intracranial hemorrhage or mortality. RS seemed considered in MT-failed internal carotid artery or middle cerebral artery M1 occlusion.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Yoonkyung Chang, Byung Moon Kim, Oh Young Bang, Jang-Hyun Baek, Ji Hoe Heo, Hyo Suk Nam, Young Dae Kim, Joonsang Yoo, Dong Joon Kim, Pyoung Jeon, Seung Kug Baik, Sang Hyun Suh, Kyung-Yul Lee, Hyo Sung Kwak, Hong Gee Roh, Young-Jun Lee, Sang Heum Kim, Chan Tags: Revascularization, Stent, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Minocycline Effects on Intracerebral Hemorrhage-Induced Iron Overload in Aged Rats Basic Sciences
This study quantified brain iron levels after ICH with magnetic resonance imaging R2* mapping. The effect of minocycline on iron overload and ICH-induced brain injury in aged rats was also determined.Methods—Aged (18 months old) male Fischer 344 rats had an intracerebral injection of autologous blood or saline, and brain iron levels were measured by magnetic resonance imaging R2* mapping. Some ICH rats were treated with minocycline or vehicle. The rats were euthanized at days 7 and 28 after ICH, and brains were used for immunohistochemistry and Western blot analyses. Magnetic resonance imaging (T2-weighted, T2* gradient-...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Shenglong Cao, Ya Hua, Richard F. Keep, Neeraj Chaudhary, Guohua Xi Tags: Basic Science Research, Intracranial Hemorrhage Original Contributions Source Type: research
Cranial Cavernous Malformations Topical Review
Source: Stroke - March 26, 2018 Category: Neurology Authors: Christopher J. Stapleton, Fred G. Barker II Tags: Cerebrovascular Malformations, Intracranial Hemorrhage Topical Reviews Source Type: research
Clinical and Technological Approaches to the Prehospital Diagnosis of Large Vessel Occlusion Topical Review
Source: Stroke - March 26, 2018 Category: Neurology Authors: Stephen van Gaal, Andrew Demchuk Tags: Diagnostic Testing, Imaging, Prognosis, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research
Accuracy of Prediction Instruments for Diagnosing Large Vessel Occlusion in Individuals With Suspected Stroke: A Systematic Review for the 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke AHA/ASA Systematic Review
Conclusions—No scale predicted LVO with both high sensitivity and high specificity. Systems that use LVO prediction instruments for triage will miss some patients with LVO and milder stroke. More prospective studies are needed to assess the accuracy of LVO prediction instruments in the prehospital setting in all patients with suspected stroke, including patients with hemorrhagic stroke and stroke mimics.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Eric E. Smith, David M. Kent, Ketan R. Bulsara, Lester Y. Leung, Judith H. Lichtman, Mathew J. Reeves, Amytis Towfighi, William N. Whiteley, Darin B. Zahuranec Tags: Statements and Guidelines AHA/ASA Systematic Review Source Type: research
Letter by Scheitz et al Regarding Article, “Randomized Controlled Trial of Early Versus Delayed Statin Therapy in Patients With Acute Ischemic Stroke: ASSORT Trial (Administration of Statin on Acute Ischemic Stroke Patient)” Letter to the Editor
Source: Stroke - February 26, 2018 Category: Neurology Authors: Jan F. Scheitz, Kennedy R. Lees, Matthias Endres Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Neuroprotectants Letters to the Editor Source Type: research
