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Source: Stroke
Condition: Hemorrhagic Stroke
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Total 995 results found since Jan 2013.
Blood Biomarkers for the Early Diagnosis of Stroke Clinical Sciences
Conclusions—The studied biomarkers were not sufficient for an accurate differential diagnosis of stroke in the hyperacute setting. Additional discovery of new biomarkers and improvement on laboratory techniques seem necessary for achieving a molecular diagnosis of stroke.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Aleȷandro Bustamante, Elena Lopez–Cancio, Sara Pich, Anna Penalba, Dolors Giralt, Teresa Garcia–Berrocoso, Carles Ferrer–Costa, Teresa Gasull, Maria Hernandez–Perez, Monica Millan, Marta Rubiera, Pedro Cardona, Luis Cano, He Tags: Biomarkers, Clinical Studies, Diagnostic Testing, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Mechanical Thrombectomy Outcomes With and Without Intravenous Thrombolysis in Stroke Patients Clinical Sciences
Conclusions—Our results demonstrated that MT+IVT patients had better functional outcomes, lower mortality, higher rate of successful recanalization, requiring lower number of device passes, and equal odds of symptomatic intracerebral hemorrhage compared with MT−IVT patients. The results support the current guidelines of offering intravenous thrombolysis to eligible patients even if they are being considered for mechanical thrombectomy. Because the data are compiled from studies where the 2 groups differed based on eligibility for intravenous thrombolysis, randomized trials are necessary to accurately evaluate the added...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Eva A. Mistry, Akshitkumar M. Mistry, Mohammad Obadah Nakawah, Rohan V. Chitale, Robert F. James, John J. Volpi, Matthew R. Fusco Tags: Revascularization, Meta Analysis, Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research
Warfarin Use in Patients With Atrial Fibrillation Undergoing Hemodialysis Clinical Sciences
Conclusions—Our findings suggest that warfarin should be used carefully in hemodialysis patients, given the higher risk of hemorrhagic events and the lack of ability to prevent thromboembolic complications.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Chang-Yun Yoon, Juhwan Noh, Jong Hyun Jhee, Tae Ik Chang, Ea Wha Kang, Youn Kyung Kee, Hyoungnae Kim, Seohyun Park, Hae-Ryong Yun, Su-Young Jung, Hyung Jung Oh, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Changsoo Kim, Tae-Hyun Yoo Tags: Arrhythmias, Clinical Studies, Nephrology and Kidney, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Real-World Setting Comparison of Nonvitamin-K Antagonist Oral Anticoagulants Versus Vitamin-K Antagonists for Stroke Prevention in Atrial Fibrillation Clinical Sciences
Conclusions—This meta-analysis confirms the main findings of the randomized controlled trials of dabigatran, rivaroxaban, and apixaban in the real-world setting and, hence, strengthens their validity.
Source: Stroke - August 28, 2017 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Konstantinos Makaritsis, Konstantinos Vemmos, Patrik Michel, Gregory Y.H. Lip Tags: Arrhythmias, Secondary Prevention, Meta Analysis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research
Palliative Care for Hospitalized Patients With Stroke Clinical Sciences
This study explores patterns of palliative care utilization and death in hospitalized patients with stroke across the United States.Methods—Using the 2010 to 2012 nationwide inpatient sample databases, we included all patients discharged with stroke identified by International Classification of Diseases-Ninth Revision codes. Strokes were subclassified as ischemic, intracerebral, and subarachnoid hemorrhage. We compared demographics, comorbidities, procedures, and outcomes between patients with and without a palliative care encounter (PCE) as defined by the International Classification of Diseases-Ninth Revision code V66....
Source: Stroke - August 28, 2017 Category: Neurology Authors: Tarvinder Singh, Steven R. Peters, David L. Tirschwell, Claire J. Creutzfeldt Tags: Race and Ethnicity, Quality and Outcomes, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Genetic Inhibition of Receptor Interacting Protein Kinase-1 Reduces Cell Death and Improves Functional Outcome After Intracerebral Hemorrhage in Mice Basic Sciences
Conclusions—The data show that the kinase domain of RIPK1 is a disease driver of ICH, mediating both acute cell death and functional outcome, and support development of RIPK1 inhibitors as therapeutic agents for human ICH.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Sevda Lule, Limin Wu, Lauren M. McAllister, William J. Edmiston III, Joon Yong Chung, Emily Levy, Yi Zheng, Peter J. Gough, John Bertin, Alexei Degterev, Eng H. Lo, Michael J. Whalen Tags: Basic Science Research, Genetically Altered and Transgenic Models, Intracranial Hemorrhage Original Contributions Source Type: research
Carbon Monoxide Preserves Circadian Rhythm to Reduce the Severity of Subarachnoid Hemorrhage in Mice Basic Sciences
Conclusions—Clock gene expression regulates, in part, the severity of SAH and requires myeloid HO-1 activity to clear the erythrocyte burden and inhibit neuronal apoptosis. Exposure to CO rescues the loss of HO-1 and thus merits further investigation in patients with SAH.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Nils Schallner, Judith-Lisa Lieberum, David Gallo, Robert H. LeBlanc III, Patrick M. Fuller, Khalid A. Hanafy, Leo E. Otterbein Tags: Inflammation, Translational Studies, Intracranial Hemorrhage Original Contributions Source Type: research
Plasma Glial Fibrillary Acidic Protein in the Differential Diagnosis of Intracerebral Hemorrhage Brief Report
Background and Purpose—Plasma GFAP (glial fibrillary acidic protein) has recently emerged as a potential biomarker for the differentiation of acute intracerebral hemorrhage (ICH) from acute ischemic stroke (AIS). We prospectively assessed the diagnostic accuracy of GFAP in the differential diagnosis of ICH.Methods—Consecutive patients presenting to the emergency department within 6 hours from symptom onset were evaluated. All patients underwent extensive diagnostic work-up and were classified according to discharge diagnosis in AIS, ICH, subarachnoid hemorrhage, and stroke mimics. GFAP was also measured in healthy volu...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Aristeidis H. Katsanos, Konstantinos Makris, Dimitra Stefani, Katerina Koniari, Eleni Gialouri, Moses Lelekis, Maria Chondrogianni, Christina Zompola, Efthymios Dardiotis, Ioannis Rizos, John Parissis, Eleni Boutati, Konstantinos Voumvourakis, Georgios Ts Tags: Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research
Neutrophil-Lymphocyte Ratio and Perihematomal Edema Growth in Intracerebral Hemorrhage Brief Report
Conclusions—Higher neutrophil–lymphocyte ratio is independently associated with PHE growth. This suggests that PHE growth can be predicted using differential leukocyte counts on admission.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Aaron M. Gusdon, Gino Gialdini, Gbambele Kone, Hediyeh Baradaran, Alexander E. Merkler, Halinder S. Mangat, Babak B. Navi, Costantino Iadecola, Ajay Gupta, Hooman Kamel, Santosh B. Murthy Tags: Intracranial Hemorrhage Brief Reports Source Type: research
Influence of Renal Impairment on Outcome for Thrombolysis-Treated Acute Ischemic Stroke Brief Report
Background and Purpose—Renal dysfunction (RD) is associated with poor prognosis after stroke. We assessed the effects of RD on outcomes and interaction with low- versus standard-dose alteplase in a post hoc subgroup analysis of the ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study).Methods—A total of 3220 thrombolysis-eligible patients with acute ischemic stroke (mean age, 66.5 years; 37.8% women) were randomly assigned to low-dose (0.6 mg/kg) or standard-dose (0.9 mg/kg) intravenous alteplase within 4.5 hours of symptom onset. Six hundred and fifty-nine (19.8%) patients had moderate-to-severe R...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Susan J. Carr, Xia Wang, Veronica V. Olavarria, Pablo M. Lavados, Jorge A. Rodriguez, Jong S. Kim, Tsong-Hai Lee, Richard I. Lindley, Octavio M. Pontes-Neto, Stefano Ricci, Shoichiro Sato, Vijay K. Sharma, Mark Woodward, John Chalmers, Craig S. Anderson, Tags: Clinical Studies, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research
Translational Stroke Research Special Report
Source: Stroke - August 28, 2017 Category: Neurology Authors: Francesca Bosetti, James I. Koenig, Cenk Ayata, Stephen A. Back, Kyra Becker, Joseph P. Broderick, S. Thomas Carmichael, Sunghee Cho, Marilyn J. Cipolla, Dale Corbett, Roderick A. Corriveau, Steven C. Cramer, Adam R. Ferguson, Seth P. Finklestein, Byron D Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies, Intracranial Hemorrhage, Ischemic Stroke Special Reports Source Type: research
Use and Timing of Tracheostomy After Severe Stroke Topical Reviews
Source: Stroke - August 28, 2017 Category: Neurology Authors: Julian Bosel Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Topical Review Source Type: research
Prothrombin Complex Concentrates Use in Intracerebral Hemorrhage Controversies in Stroke
Source: Stroke - August 28, 2017 Category: Neurology Authors: Sven Poli, Florian Hartig, Magdy H. Selim, Carlos A. Molina, Dar Dowlatshahi Tags: Intracranial Hemorrhage Controversies in Stroke Source Type: research
Management of Brain Arteriovenous Malformations: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Conclusions—Brain arteriovenous malformations are a relatively uncommon but important cause of hemorrhagic stroke, especially in young adults. This statement describes the current knowledge of the natural history and treatment of patients with ruptured and unruptured brain arteriovenous malformations, suggestions for management, and implications for future research.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Colin P. Derdeyn, Gregory J. Zipfel, Felipe C. Albuquerque, Daniel L. Cooke, Edward Feldmann, Jason P. Sheehan, James C. Torner Tags: Statements and Guidelines AHA/ASA Scientific Statement Source Type: research
Correction to: THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage Correction
Source: Stroke - July 24, 2017 Category: Neurology Tags: Corrections Source Type: research
