• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Vascularization Pattern After Ischemic Stroke is Different in Control Versus Diabetic Rats: Relevance to Stroke Recovery Basic Sciences
Conclusions— Diabetes mellitus impairs poststroke reparative neovascularization and impedes the recovery. Glycemic control after stroke can improve neurovascular repair and improve functional outcome.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Prakash, R., Li, W., Qu, Z., Johnson, M. A., Fagan, S. C., Ergul, A. Tags: Type 2 diabetes, Behavioral Changes and Stroke, Other imaging, Other Vascular biology Basic Sciences Source Type: research

Endoglin Deficiency Impairs Stroke Recovery Basic Sciences
Conclusions— Endoglin deficiency impairs brain injury recovery. Reduced angiogenesis, impaired macrophage homing, and delayed inflammation resolution could be the underlying mechanism.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Shen, F., Degos, V., Chu, P.-L., Han, Z., Westbroek, E. M., Choi, E.-J., Marchuk, D., Kim, H., Lawton, M. T., Maze, M., Young, W. L., Su, H. Tags: Cerebrovascular disease/stroke, Animal models of human disease, Genetically altered mice, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Basic Sciences Source Type: research

Hyperglycemia and PPAR{gamma} Antagonistically Influence Macrophage Polarization and Infarct Healing After Ischemic Stroke Basic Sciences
Conclusions— Hyperglycemia and macrophage-specific PPAR activation exert opposing effects on MO/MP polarization in ischemic stroke lesions and, thereby, critically determine the risk of hemorrhagic infarct transformation.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Gliem, M., Klotz, L., van Rooijen, N., Hartung, H.-P., Jander, S. Tags: Animal models of human disease, Coumarins, Other diabetes, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Anticoagulants Basic Sciences Source Type: research

Predictive Factors for Rebleeding After Aneurysmal Subarachnoid Hemorrhage: Rebleeding Aneurysmal Subarachnoid Hemorrhage Study Clinical Sciences
Conclusions— In our opinion, timing of treatment of aSAH patients, especially those with an modified Fisher grade of 3 or 4 in a good clinical condition, should be reconsidered. These aSAH patients might be regarded a medical emergency, requiring aneurysm repair as soon as possible. In this respect, our findings should provoke the debate on timing of aneurysm repair, especially in patients considered to be at high risk for rebleeding.
Source: Stroke - July 27, 2015 Category: Neurology Authors: van Donkelaar, C. E., Bakker, N. A., Veeger, N. J. G. M., Uyttenboogaart, M., Metzemaekers, J. D. M., Luijckx, G.-J., Groen, R. J. M., van Dijk, J. M. C. Tags: Acute Cerebral Hemorrhage, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Emergency treatment of Stroke, Aneurysm, AVM, hematoma Clinical Sciences Source Type: research

Variability in Outcome After Elective Cerebral Aneurysm Repair in High-Volume Academic Medical Centers Clinical Sciences
Conclusions— There is notable interhospital heterogeneity in outcomes among even the largest volume unruptured intracranial aneurysm referral centers. Although further regionalization may be needed, mandatory participation in prospective, adjudicated registries will be necessary to reliably identify factors associated with superior outcomes.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Zacharia, B. E., Bruce, S. S., Carpenter, A. M., Hickman, Z. L., Vaughan, K. A., Richards, C., Gold, W. E., Lu, J., Appelboom, G., Solomon, R. A., Connolly, E. S. Tags: Health policy and outcome research, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Clinical Sciences Source Type: research