Stroke RSS Page 13

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Condition: Hemorrhagic Stroke
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Total 250 results found since Jan 2013.

Long-term motor, functional, and academic outcome following childhood ischemic and hemorrhagic stroke: A large rehabilitation center-based retrospective study
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Source: Developmental Neurorehabilitation - November 13, 2016 Category: Neurology Authors: Estelle Yvon Delphine Lamotte Anne Tiberghien Ingrid Godard Alain Mardaye Anne Laurent-Vannier Maria De Agostini Mathilde Chevignard Source Type: research

AEDs after ICH: Preventing the prophylaxis
Has the routine use of antiepileptic drugs (AEDs) in intracerebral hemorrhage (ICH) become a habit too difficult to break? Adherents to evidence-based medicine must surely have a conniption in light of this continuing practice. The guidelines have remained clear over the years: Do not use antiseizure medications in ICH unless there has been a seizure. Yet prophylactic AED use after acute ICH remains widespread in the United States. This is brought to our attention in the current issue of Neurology®. Naidech et al.1 report on the patterns of AED use in ICH over 5 years across several academic medical centers in Chicago....
Source: Neurology - December 25, 2016 Category: Neurology Authors: Koch, S., Sung, G. Tags: Critical care, Antiepileptic drugs, Intracerebral hemorrhage EDITORIALS Source Type: research

Race/Ethnicity as a Predictor for Location of Death in Patients With Acute Neurovascular Events.
CONCLUSION: This study did not show a difference in site of death in our institution by race or ethnicity, which is considered an important quality end-of-life care metric. PMID: 28056515 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - December 31, 2016 Category: Palliative Care Authors: Salomon S, Chuang E, Bhupali D, Labovitz D Tags: Am J Hosp Palliat Care Source Type: research

Nico launches trial for brain surgery shunt
Nico Corp said today it enrolled the 1st patient in the Enrich clinical trial which aims to explore the use of its BrainPath Approach for treating intracerebral hemorrhages. The trial will examine the procedural safety as well as economic and functional benefit of early surgical removal of intracerebral hemorrhages using its BrainPath Approach system. “Our initial clinical results with this approach for early clot removal have been exciting and provided a wake-up call to what has been missing in hemorrhagic stroke care,” trial principal investigator Dr. Daniel Barrow said in a press release. Indianapolis, I...
Source: Mass Device - January 10, 2017 Category: Medical Equipment Authors: Fink Densford Tags: Clinical Trials Neurological Nico Corp. Source Type: news

Organovo CEO Murphy steps away, Crouch steps up | Personnel Moves – April 14, 2017
Organovo (PINK:ONVO) said earlier this week that Taylor Crouch has been appointed as CEO, replacing Keith Murphy who is stepping away from the company. The changes are slated to go into effect on April 21. Prior to being tapped for the corner office, Crouch operated as CEO of investigative clinical research company eStudySite, the San Diego, Calif.-based company said. “I am extremely proud of the progress we have made in the last ten years achieving our vision for Organovo. Our 3D bioprinted human tissues are a disruptive and game-changing technology. Founding Organovo and guiding us to our leadership position...
Source: Mass Device - April 14, 2017 Category: Medical Equipment Authors: MassDevice staff Tags: Business/Financial News Active Implants AdvaMed Alphatec Holdings Inc. Anika Therapeutics Inc. Apollo Endosurgery Aurora Spine Baxter Biocorp Biogen Idec Biolase Technology Inc Bioventus LLC Bonesupport Clal Biotech Delcath Sys Source Type: news

Early Clinical Improvement in Central Retinal Artery Occlusion is Associated with Central Retinal Artery Recanalization (P4.262)
Conclusions:In our case series, no patient without early recanalization of the CRA had ECI. Further studies are merited to determine the impact of CRA recanalization timing and, furthermore, whether fibrinolytic therapy is associated with improved CRA recanalization rates and long-term visual acuity in CRAO patients.Disclosure: Dr. Alkuwaiti has nothing to disclose. Dr. Male has nothing to disclose. Dr. Hendriksen has nothing to disclose. Dr. Engel has nothing to disclose. Dr. Reshi has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air Liquide as a Scientific Advisory Board membe...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alkuwaiti, M., Male, S., Hendriksen, S., Engel, K., Reshi, R. A., Ezzeddine, M., Emiru, T., Logue, C., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Elevated ventricular CSF lactate within the first week after aneurysmal subarachnoid hemorrhage is associated with poor outcome (P5.068)
Conclusions:Elevated CSF lactate drawn within the first week of hospitalization following aSAH correlates with outcome. Larger prospective studies are needed to test the validity of this data for predicting outcome and for understanding the pathophysiologic mechanisms.Study Supported by: No funding was received for this study.Disclosure: Dr. Renfrow has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Arnel has nothing to disclose. Dr. Wolfe has nothing to disclose. Dr. Datar has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Renfrow, J., Wilson, T., Arnel, M., Wolfe, S., Datar, S. Tags: Neurocritical Care: Subarachnoid Hemorrhage Source Type: research

Association between Leucocyte Count and Perihematomal Edema Growth After Primary Intracerebral Hemorrhage (N8.001)
Conclusions:Higher admission leucocyte count, particularly monocyte count, is associated with PHE growth. This suggests a potential role of inflammation in modulating PHE after ICH.Study Supported by: American Academy of Neurology and American Brain Foundation Clinical Research Training FellowshipDisclosure: Dr. Gusdon has nothing to disclose. Dr. Gialdini has nothing to disclose. Dr. Baradaran has nothing to disclose. Dr. Merkler has nothing to disclose. Dr. Iadecola has received personal compensation in an editorial capacity for the Journal of Neuroscience. Dr. Navi has nothing to disclose. Dr. Gupta has nothing to discl...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gusdon, A., Gialdini, G., Baradaran, H., Merkler, A., Iadecola, C., Navi, B., Gupta, A., Kamel, H., Murthy, S. Tags: Neuroscience in the Clinic: Novel Therapeutic Targets in Critical Care Neurology: Intracerebral and Intraventricular Hemorrhage Source Type: research

Role Of Sulfonylureas In Perihematomal Edema In Spontaneous Intracerebral Hemorrhage (N8.002)
Conclusions:Our study shows a trend towards decreased absolute PHE and better clinical outcomes in ICH patients with diabetes who are taking SUs. However, our findings are limited by the study design, low power, and imbalances in baseline ICH volume. Further studies are required to evaluate the role of SUs in attenuating PHE.Disclosure: Dr. Male has nothing to disclose. Dr. Robertson has nothing to disclose. Dr. Alkuwaiti has nothing to disclose. Dr. Bell has nothing to disclose. Dr. Lindsay has nothing to disclose. Dr. Reshi has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Male, S., Robertson, J., Alkuwaiti, M., Bell, C., Lindsay, D., Reshi, R., Ezzeddine, M., Streib, C. Tags: Neuroscience in the Clinic: Novel Therapeutic Targets in Critical Care Neurology: Intracerebral and Intraventricular Hemorrhage Source Type: research

Retrospective Validation of a Computer-Assisted Quantification Model of Intracerebral Hemorrhage Volume on Accuracy, Precision, and Acquisition Time, Compared with Standard ABC/2 Manual Volume Calculation ADULT BRAIN
CONCLUSIONS: SegTool appears to have attributes superior to ABC/2 in terms of accuracy and interrater reliability with a 9-second delay in measurement time (on average); hence, it could be useful in clinical trials and practice.
Source: American Journal of Neuroradiology - August 14, 2017 Category: Radiology Authors: Xue, W., Vegunta, S., Zwart, C. M., Aguilar, M. I., Patel, A. C., Hoxworth, J. M., Demaerschalk, B. M., Mitchell, J. R. Tags: ADULT BRAIN Source Type: research

Impact of Moderate Hyperchloremia on Clinical Outcomes in Intracerebral Hemorrhage Patients Treated With Continuous Infusion Hypertonic Saline: A Pilot Study
Conclusions: We observed higher rates of in-hospital mortality in patients who developed moderate hyperchloremia during treatment with continuous IV infusion 3% hypertonic saline, with moderate hyperchloremia independently predicting in-hospital mortality. These results suggest that chloride values should be monitored closely during hypertonic saline treatment as moderate elevations may impact outcomes in intracerebral hemorrhage patients.
Source: Critical Care Medicine - August 17, 2017 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Prophylactic Anticonvulsants in Intracerebral Hemorrhage
DiscussionLevetiracetam was routinely prescribed following ICH and was not associated with worse outcomes. Future investigations should examine the effect of prophylactic levetiracetam on cost and neuropsychological outcomes as well as the role of continuous EEG in identifying subclinical seizures.
Source: Neurocritical Care - October 1, 2017 Category: Neurology Source Type: research

E-039 Comparison of predictive grading systems for procedural risk in endovascular treatment of brain arteriovenous malformations - analysis of 104 consecutive patients
Conclusion Our independent analysis of 104 patients with brain AVMs treated with endovascular embolization validates the predictive capacity of the Buffalo score, but not AVMN or SM grades, for endovascular embolization procedural risk. This will allow for better stratification of brain AVM patients by procedural risk, and will ultimately result in safer care of these patients. Complications(n=25) No complications(n=79) P-value Age ± SD 46.0±16.9 42.3±15.9 0.33 Female gender, N (%) 7 (28) 38 (48) 0.12 Left side, N (%) 14 (56) 41 (52) 0.90 Spetzler-Martin grade, median (IQR) 3 (2–3) 2 (2–...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Pulli, B., Stapleton, C., Koch, M., Patel, A. Tags: Electronic Poster Abstracts Source Type: research

Impact of Asynchronous Training on Radiology Learning Curve among Emergency Medicine Residents and Clerkship Students.
CONCLUSION: Incorporating asynchronous WBL modules into EM clerkship and residency curriculum provides early radiographic exposure in their clinical training and can enhance diagnostic head CT scan interpretation. PMID: 29272248 [PubMed - in process]
Source: The Permanente journal - December 24, 2017 Category: General Medicine Tags: Perm J Source Type: research

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