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Condition: Ischemic Stroke
Nutrition: Antidoxidants
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Total 671 results found since Jan 2013.
The Bioactivities of Phycocyanobilin from Spirulina
J Immunol Res. 2022 Jun 11;2022:4008991. doi: 10.1155/2022/4008991. eCollection 2022.ABSTRACTPhycocyanobilin (PCB) is a linear open-chain tetrapyrrole chromophore that captures and senses light and a variety of biological activities, such as anti-oxidation, anti-cancer, and anti-inflammatory. In this paper, the biological activities of PCB are reviewed, and the related mechanism of PCB and its latest application in disease treatment are introduced. PCB can resist oxidation by scavenging free radicals, inhibiting the activity of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and delaying the activity of antiox...
Source: Journal of Immunology Research - June 21, 2022 Category: Allergy & Immunology Authors: Yi Li Source Type: research
Edaravone, a scavenger for multiple reactive oxygen species, reacts with singlet oxygen to yield 2-oxo-3-(phenylhydrazono)-butanoic acid
In this study, we investigated the reactivity of edaravone toward 1O2 and identified its reaction products. Edaravone showed a reactivity toward 1O2 greater than those of uric acid, histidine, and tryptophan, which are believed to be 1O2 scavengers in vivo. And we confirmed that 2-oxo-3-(phenylhydrazono)-butanoic acid was formed as an oxidation product. We propose a plausible mechanism for 2-oxo-3-(phenylhydrazono)-butanoic acid production by 1O2-induced edaravone oxidation. Since 2-oxo-3-(phenylhydrazono)-butanoic acid has already been identified as a radical-initiated oxidation product, free radical-induced oxidati...
Source: Clinical Biochemistry - June 13, 2022 Category: Biochemistry Authors: Sakiko Amekura Kyouhei Shiozawa Chihiro Kiryu Yorihiro Yamamoto Akio Fujisawa Source Type: research
