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Prognostic prediction of thrombolytic therapy with rt-PA in acute ischemic stroke patients using an artificial intelligence model
CONCLUSIONS: ANN model is as effective as a logistic regression model in predicting the prognosis of AIS after thrombolytic therapy with rt-PA. Moreover, ANN is slightly superior to logistic regression in accuracy, precision and F1 score.PMID:37560207 | PMC:PMC10408517
Source: American Journal of Translational Research - August 10, 2023 Category: Research Authors: Miao Chen Liya Zhou Limin Fan Yanhong Li Hairong Wang Source Type: research

Development of a decision analytic model to support decision making and risk communication about thrombolytic treatment
Conclusions: We have produced a DAM that provides an estimation of the likely benefits and risks of thrombolysis for individual patients, which has subsequently been embedded in a computerised decision aid to support better decision-making and informed consent.
Source: BMC Medical Informatics and Decision Making - November 11, 2015 Category: Information Technology Authors: Peter McMeekinDarren FlynnGary FordHelen RodgersJo GrayRichard Thompson Source Type: research

Homocysteine-lowering therapy and early functional outcomes of ischemic patients with H-type hypertension: a retrospective analysis of CNSR
This study evaluated the effects of HLT during hospitalization on the early outcomes of the 792 ischemic stroke patients with H-type hypertension from the China National Stroke Registry. The subjects were divided into HLT and non-HLT groups. Demographic and laboratory information were collected, while the functional outcome at discharge and at 90 days follow-up were assessed by National Institutes of Health Stroke Scale and modified Rankin Scale (mRS) in both groups. We found that in the univariate analysis, the proportions of patients with good functional outcomes (mRS = 0–2) were 31.68 versus 29.36 % (OR 0.90, 95 ...
Source: Australasian Physical and Engineering Sciences in Medicine - December 7, 2015 Category: Biomedical Engineering Source Type: research

Maximizing First-Pass Complete Reperfusion with SAVE
ConclusionSAVE is fast and appears to be very effective in terms of first-pass complete reperfusion in patients with LVO.
Source: Clinical Neuroradiology - February 12, 2017 Category: Neurology Source Type: research

Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion
ConclusionReperfusion is the major predictor of functional outcome in BAO in clinical practice. Failed recanalization resulted in a  13-fold increase of the risk of poor outcome. Successful recanalization is crucial to achieve a better functional outcome in BAO.
Source: Clinical Neuroradiology - December 22, 2019 Category: Neurology Source Type: research

The clinical and cognitive spectrum of locked-in syndrome: 1-year follow-up of 100 patients
AbstractIn patients with locked-in syndrome (LIS), it is not known exactly to what extent cognitive functions are preserved and it is not known exactly how much it has improved. We aimed to examine the clinical and cognitive features of LIS 1 year after stroke. One hundred patients with locked-in syndrome (LIS) were recruited between January 2008 and May 2019 among 8200 patients with ischemic stroke. Patients were classified into two groups as single pontine infarcts (n = 72), and pontine plus multiple ischemic lesions (PMIL) (n = 28). Since the patients had limited motor and verbal response, the cognitive status o...
Source: Acta Neurologica Belgica - May 13, 2021 Category: Neurology Source Type: research

Preexisting cognitive impairment in intracerebral hemorrhage
ConclusionsIn conclusion, cognitive impairment frequently precedes ICH. A higher frequency of cerebrovascular events suggests a role of vascular processes in the development of cognitive impairment before ICH.
Source: Acta Neurologica Scandinavica - August 9, 2016 Category: Neurology Authors: M. Laible, S. Horstmann, M. M öhlenbruch, S. Schueler, T. Rizos, R. Veltkamp Tags: Original Article Source Type: research

Maximum lesions area and orthogonal values accessed from DWI images would be alternative imaging markers for predicting the outcome of acute ischemia in the middle cerebral artery territory.
Conclusion Since they correlated well with the infarction volume, MaxA and OD assessed on DWI were time-saving and achieved comparable diagnostic efficiencies; thus, they may represent alternative imaging markers for predicting unfavorable outcomes of acute ischemic stroke in MCA territory. PMID: 30130971 [PubMed - as supplied by publisher]
Source: Acta Radiologica - August 21, 2018 Category: Radiology Authors: Yuan T, Ren G, Quan G, Liu Y Tags: Acta Radiol Source Type: research

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