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Source: Journal of Clinical Neuroscience
Condition: Ischemic Stroke
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Total 164 results found since Jan 2013.
Magnetisation transfer parameters and stroke outcome
Publication date: Available online 16 April 2015 Source:Journal of Clinical Neuroscience Author(s): I. Sibon , T. Tourdias , S. Felix , J. Asselineau , L. Bracoud , A. Vivot , F. Rouanet , P. Renou , J.M. Orgogozo , V. Dousset Our aim was to evaluate the association between magnetisation transfer imaging (MTI) parameters measured 30 to 45days after a cerebrovascular insult and post-stroke functional outcome at the same time. MTI offers the opportunity to depict subtle microstructural changes in infarcted areas. The clinical significance of the heterogeneity of brain damage within ischaemic stroke lesions is unknown. We p...
Source: Journal of Clinical Neuroscience - April 28, 2015 Category: Neuroscience Source Type: research
High-resolution MRI of the vessel wall in patients with symptomatic atherosclerotic stenosis of the middle cerebral artery
Publication date: Available online 2 March 2015 Source:Journal of Clinical Neuroscience Author(s): Deng-Ling Zhao , Gang Deng , Bo Xie , Shenghong Ju , Ming Yang , Xiao-Hui Chen , Gao-Jun Teng Intracranial atherosclerosis is associated with recurrent ischemic stroke. High-resolution MRI (HR MRI) can provide information about atheroma in vivo. We aimed to analyze and compare vascular wall imaging characteristics between patients with symptomatic and asymptomatic atherosclerotic stenosis of the middle cerebral artery (MCA) using 3.0 Tesla HR MRI. The HR MRI protocol included four different scans: black blood T1-weighted, T...
Source: Journal of Clinical Neuroscience - March 2, 2015 Category: Neuroscience Source Type: research
Ischemic stroke related to an amniotic fluid embolism during labor
We report a young woman who survived multiple cerebral infarctions related to an amniotic fluid embolism (AFE) during labor. To our knowledge, an embolic stroke due to the coexistence of an AFE and patent foramen ovale (PFO) has not been reported. We describe the patient’s clinical and radiological features and discuss the stroke mechanism in relation to our AFE hypothesis. A 32-year-old woman presented to the emergency room after experiencing convulsions during labor (blood pressure, 64/28mmHg; oxygen saturation, 67%). She was in a stupor, and her response to painful stimuli on the right side was weaker than on the left...
Source: Journal of Clinical Neuroscience - February 21, 2015 Category: Neuroscience Source Type: research
In-hospital outcomes of thrombolysis for acute ischemic stroke in patients with primary brain tumors
Publication date: March 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 3 Author(s): Santosh B. Murthy , Yogesh Moradiya , Shreyansh Shah , Aditi Shastri , Eric M. Bershad , Jose I. Suarez Data on thrombolysis outcomes in patients with primary brain tumors are limited. Our aim was to study stroke outcomes following thrombolysis in these patients in a population-based study. Patients with acute ischemic stroke who received thrombolysis were identified from the 2002–2011 USA Nationwide Inpatient Sample. We compared demographics, comorbidities, and outcomes between primary brain tumor-associated strokes (BT...
Source: Journal of Clinical Neuroscience - February 16, 2015 Category: Neuroscience Source Type: research
Association between hemoglobin A1C levels and clinical outcome in ischemic stroke patients with or without diabetes
We examined whether chronic hyperglycemia, measured in terms of hemoglobin A1C (HbA1C) levels, influences clinical outcomes after acute ischemic stroke. We prospectively and consecutively included patients admitted within 7days of ischemic stroke onset. Demographic and clinical information and outcomes were analyzed separately for patients with or without diabetes in order to identify associations with HbA1C tercile. A total of 1351 patients without diabetes and 526 with diabetes were included. The risk of mortality and poor outcome showed a tendency to increase with increasing HbA1C tercile in both groups. Rates of mortal...
Source: Journal of Clinical Neuroscience - February 16, 2015 Category: Neuroscience Source Type: research
A male Fabry disease patient treated with intravenous thrombolysis for acute ischemic stroke
We report a 38-year-old man with acute aphasia and a left M2 segment of the middle cerebral artery thrombus with no recanalization who was finally diagnosed with Fabry disease after left ventricular hypertrophy of undetermined cause had been identified. A gene test revealed a R227X mutation typical of Fabry disease with the classical phenotype. To our knowledge our patient is the first reported male Fabry patient who was given intravenous thrombolytic therapy and the first reported Fabry patient who received intravenous thrombolytic therapy between 3 and 4.5hours of the symptom onset. Despite favorable prognostic indicator...
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research
National data on stroke outcomes in Thailand
In conclusion, the prevalence and outcomes of stroke in Thailand were comparable with other countries. The era of thrombolytic therapy has just begun in Thailand.
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research
Downregulation of serum brain specific microRNA is associated with inflammation and infarct volume in acute ischemic stroke
Publication date: February 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 2 Author(s): Yanping Liu , Junjian Zhang , Rongfei Han , Hanxing Liu , Dong Sun , Xuan Liu Cerebral ischemic injury activates a robust inflammatory response, exacerbating neurological deficit. Several brain specific microRNA (miRNA) molecules have been reported to mediate functioning of the immune system, referred to as NeurimmiR. We aimed to explore possible associations between serum miRNA levels and stroke severity and their involvement in the regulation of inflammatory responses after stroke. Blood samples were obtained from 31 ...
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research
Clinical presentation and imaging characteristics of occult lung cancer associated ischemic stroke
Publication date: February 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 2 Author(s): Hui Mai , Jun Xia , Yongjun Wu , Junlong Ke , Junliang Li , Jiangang Pan , Wubiao Chen , Yiming Shao , Zhi Yang , Saihua Luo , Yonghua Sun , Bin Zhao , Longxuan Li We investigated the clinical and imaging characteristics of initial and recurrent strokes in patients with occult lung cancer associated ischemic stroke (OLCA-stroke). A retrospective review of all ischemic stroke patients with occult lung cancer in the absence of conventional stroke etiologies between 2005 and 2013 was conducted. We compared the initial and ...
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research
Remote intracerebral haemorrhage post intravenous thrombolysis: Experience from an Australian stroke centre
Publication date: February 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 2 Author(s): Yuan Gao , Leonid Churilov , Sarah Teo , Bernard Yan Remote intracerebral haemorrhage (rICH) is defined as intracerebral haemorrhage (ICH) post thrombolysis in brain regions without visible ischaemic changes. There is uncertainty that clinical outcomes and risk factors for rICH are different to those for local ICH. We investigated the morbidity, mortality and factors associated with rICH. We hypothesised that a previous history of cerebral ischaemic events is associated with increased risk of rICH. We included consecuti...
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research
Increased risk of ischemic stroke in patients with pneumoconiosis
Publication date: February 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 2 Author(s): Yuan-Yang Cheng , Kuo-Hsuan Hsu , Yi-Huei Chen , Ching-Heng Lin Although past studies have confirmed that chronic dust exposure is a risk factor for cardiovascular disease, the relationship between it and cerebrovascular disease is still unclear. We aimed to determine whether pneumoconiosis is related to increased incidence of ischemic stroke in the following 5 to 11years. We selected 1238 patients with pneumoconiosis from Taiwan’s National Health Insurance database as our study cohort. After matching for age, sex and...
Source: Journal of Clinical Neuroscience - January 14, 2015 Category: Neuroscience Source Type: research
Saving the ischemic penumbra: Endovascular thrombolysis versus medical treatment
We present the first study to our knowledge comparing the ischemic penumbra saved with endovascular versus medical therapy. A retrospective review of 21 patients undergoing endovascular intervention for stroke from 2010 to 2011 was contrasted with 21 consecutive patients treated with antiplatelet agents alone. Immediate computed tomography perfusion (CTP) scan of the head and neck was obtained in all patients. Patients with lacunar and posterior circulation infarcts, and those who were medically unstable for MRI post-operatively were excluded. CTP and MRI underwent volumetric calculation. CTP penumbra was correlated with d...
Source: Journal of Clinical Neuroscience - November 29, 2014 Category: Neuroscience Source Type: research
Ischemic complications after tailored carotid artery stenting in different subpopulations with high-grade stenosis: Feared but rare
Publication date: Available online 28 November 2014 Source:Journal of Clinical Neuroscience Author(s): José E. Cohen , J. Moshe Gomori , Eyal Itshayek , Stylianos Pikis , Galina Keigler , Roni Eichel , Ronen R. Leker Although the procedural and postoperative safety profile of carotid artery stenting (CAS) has been steadily improving, many centers still recommend carotid endarectomy (CEA) over CAS. We assessed outcomes (procedural and postoperative stroke) following tailored CAS in a cohort of patients managed at a single academic medical center. Outcomes for patients with carotid artery stenosis treated from 2005–2013...
Source: Journal of Clinical Neuroscience - November 29, 2014 Category: Neuroscience Source Type: research
Successful endovascular repair of an unusual right-to-left shunt presenting with cerebral ischemia
We report a 54-year-old man with a stroke due to a unique right-to-left shunt who underwent successful endovascular treatment. This patient developed acute onset of right arm weakness with facial droop and aphasia which improved after intravenous thrombolysis. An MRI showed acute cerebral ischemia in the left middle cerebral artery and left posterior cerebral artery distribution. The patient developed recurrent stroke symptoms during agitated saline injection while undergoing a transthoracic echocardiogram which showed right-to-left shunting. Chest CT scan and conventional angiography revealed near occlusion of the superio...
Source: Journal of Clinical Neuroscience - November 3, 2014 Category: Neuroscience Source Type: research
