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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Ischemic Stroke

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Total 2464 results found since Jan 2013.

The Impact of Diabetes on Outcomes After Acute Ischemic Stroke: A Prospective Observational Study
Background: Stroke in diabetics may delay recovery and increases the risk of early recurrence of stroke. We compared the outcomes of patients (with and without diabetes) admitted with an acute ischemic stroke (AIS) in the state of Qatar. Patients and methods: We prospectively compared the clinical presentation, complications, discharge outcome, and stroke recurrence at 90 days in patients with and without diabetes. Results: Five thousand two hundred twenty-eight stroke patients were admitted between January 2014 and December 2017.
Source: Journal of Stroke and Cerebrovascular Diseases - December 10, 2018 Category: Neurology Authors: Naveed Akhtar, Saadat Kamran, Rajvir Singh, Rayaz A. Malik, Dirk Deleu, Paula J. Bourke, Sujatha Joseph, Mark D. Santos, Deborah M. Morgan, Faisal M. Wadiwala, Reny Francis, Blessy M. Babu, Pooja George, Rumissa Ibrahim, Pablo Garcia-Bermejo, Ashfaq Shuai Source Type: research

Serum Troponin Level in Acute Ischemic Stroke Identifies Patients with Visceral Infarcts
Background and Purpose: Patients with ischemic stroke of cardioembolic origin are at risk of visceral (renal or splenic) infarction. We hypothesized that serum troponin level at time of ischemic stroke would be associated with presence of visceral infarction. Methods: Data were abstracted from a single center prospective stroke database over 18 months and included all patients with ischemic stroke who underwent contrast-enhanced computerized tomography (CT) of the abdomen and pelvis for clinical purposes within 1 year of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2019 Category: Neurology Authors: Idrees Azher, Ashutosh Kaushal, Andrew Chang, Shawna Cutting, Brian Mac Grory, Tina Burton, Katarina Dakay, Bradford Thompson, Michael Reznik, Linda Wendell, Nicholas Stevenson Potter, Ali Mahta, Shyam Rao, Maurizio Paciaroni, Mitchell S.V. Elkind, Mahesh Source Type: research

Leukoaraiosis Predicts Short-term Cognitive But not Motor Recovery in Ischemic Stroke Patients During Rehabilitation
Background: Leukoaraiosis has been shown to impact functional outcomes after acute ischemic stroke. However, its association with domain specific recovery after ischemic stroke is uncertain. We sought to determine whether pre-existing leukoaraiosis is associated with short-term motor and cognitive recovery after stroke. Methods: We retrospectively studied ischemic stroke patients admitted to acute inpatient rehabilitation (AIR) between January 2013 and September 2015. Patient baseline characteristics, infarct volume, prestroke modified Rankin Scale, stroke cause, rehabilitation length of stay, and Functional Independence M...
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2019 Category: Neurology Authors: Muhib Khan, Heather Heiser, Nathan Bernicchi, Laurel Packard, Jessica L. Parker, Matthew A. Edwardson, Brian Silver, Kost V. Elisevich, Nils Henninger Source Type: research

Total Antioxidant Capacity Predicts Outcome in Acute Ischemic Stroke Subtypes in Egyptian Patients
Background: Oxidative stress after ischemic stroke contributes to neuronal cell injury. We tried to demonstrate an association between total antioxidant capacity (TAC) levels and outcomes after acute ischemic stroke (AIS). Methods: We enrolled 60 patients (36 females and 24 males) who were admitted to our hospital due to AIS, in addition to 30 age and sex-matched healthy controls. TAC levels were measured on day 1 of stroke onset, the relationships between TAC levels, stroke subtypes, and clinical outcomes based on the National Institutes of Health Stroke Scale and modified Rankin scale upon discharge were evaluated.
Source: Journal of Stroke and Cerebrovascular Diseases - April 19, 2019 Category: Neurology Authors: Nesma A.M. Ghonimi, Mohamed E. Mahdy, Osama A. Abdel Salam Source Type: research

Co-Effect of Serum Galectin-3 and High-Density Lipoprotein Cholesterol on the Prognosis of Acute Ischemic Stroke
This study aimed to evaluate the coeffect of galectin-3 and HDL-C on death and vascular events within 1 year after ischemic stroke. Materials and Methods: Based on China Antihypertensive Trial in Acute Ischemic Stroke, a prospective study was conducted among 2970 patients with acute ischemic stroke. The primary outcome was a combination of death and vascular events within 1 year after ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2019 Category: Neurology Authors: Nimei Zeng, Aili Wang, Tan Xu, Chongke Zhong, Xiaowei Zheng, Zhengbao Zhu, Yanbo Peng, Hao Peng, Qunwei Li, Zhong Ju, Deqin Geng, Yonghong Zhang, Jiang He Source Type: research

High Detection Rate of Atrial Fibrillation With Insertable Cardiac Monitor Implantation in Patients With Cryptogenic Stroke Diagnosed by Magnetic Resonance Imaging
Background: Detection and treatment of atrial fibrillation (AF) is a major goal in preventing secondary stroke. Insertable cardiac monitors (ICMs) are available for diagnosis of arrhythmia monitoring in patients with cryptogenic stroke. Magnetic resonance imaging (MRI)-based diagnostic evaluation for acute ischemic stroke subtype classification is common in Japan and can be useful for specific diagnosis of cryptogenic stroke. Purpose: We aimed to investigate the detection rate of AF with an ICM in patients with cryptogenic stroke who were diagnosed by MRI.
Source: Journal of Stroke and Cerebrovascular Diseases - June 20, 2019 Category: Neurology Authors: Tomonori Iwata, Kenichi Todo, Hiroshi Yamagami, Masafumi Morimoto, Tetsuya Hashimoto, Ryosuke Doijiri, Hiroyuki Furuya Source Type: research

A Narrative Review of Nonvitamin K Antagonist Oral Anticoagulant Use in Secondary Stroke Prevention
The prevalence of atrial fibrillation (AF), the most common cardiac arrhythmia, increases with age, predisposing elderly patients to an increased risk of embolic stroke. With an increasingly aged population the number of people who experience a stroke every year, overall global burden of stroke, and numbers of stroke survivors and related deaths continue to increase. Anticoagulation with vitamin K antagonists (VKAs) reduces the risk of ischemic stroke in patients with AF; however, increased bleeding risk is well documented, particularly in the elderly.
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2019 Category: Neurology Authors: Valeria Caso, Florian Masuhr Tags: Review Article Source Type: research

Comment on: External Validation of the PREMISE Score in the Athens Stroke Registry
This study externally validated our proposed predicting early mortality from ischemic stroke (PREMISE) score, derived from the nationwide Austrian Stroke Unit registry.2 While we feel obliged to point out that the original PREMISE score publication2 was incorrectly referenced3 by Ntaios et al, it is reassuring that the authors confirmed prognostic accuracy (with excellent calibration and good discrimination) of the PREMISE score as an instrument for predicting early (within one week after admission) death after ischemic stroke in 2608 patients from the Athens Stroke Unit registry.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2019 Category: Neurology Authors: Thomas Gattringer, Alexandra Posekany, Stefan Kiechl, Franz Fazekas, Christian Enzinger Tags: Letter to the Editor Source Type: research

Clinical Utility of the Inflammatory Factors Combined With Lipid Markers in the Diagnostic and Prognostic Assessment of Ischemic Stroke: Based on Logistic Regression Models
In this study, we developed novel logistic regression models for the diagnostic and prognostic assessment of ischemic stroke. Methods: A total of 288 ischemic stroke patients and 300 controls admitted to The First Affiliated Hospital of Soochow University were included in the testing group. Two validation groups from The Affiliated Kunshan Hospital of Jiangsu University and The Second Affiliated Hospital of Soochow University were included to assess our novel assessment models. Results: Results from the testing group indicated that the diagnostic assessment model for ischemic stroke prediction was: Logit(P)  = 437.116...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2020 Category: Neurology Authors: Zhaoxi Ma, Yushan Yue, Yan Luo, Wanhua Wang, Yongjun Cao, Qi Fang Source Type: research

BE-FAST: A Sensitive Screening Tool to Identify In-Hospital Acute Ischemic Stroke
This study aims to assess the validity of BE-FAST (Balance, Eyes, Face, Arm, Speech, Time) as a screening tool for acute ischemic stroke among inpatients.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Faten El Ammar, Agnieszka Ardelt, Victor J. Del Brutto, Andrea Loggini, Zachary Bulwa, Raisa C. Martinez, Cedric J. McKoy, James Brorson, Ali Mansour, Fernando D. Goldenberg Source Type: research

Determinants of preventable stroke —Ankara ACROSS stroke preventability study
In this study, we analyzed pre-event clinical features that play a role in stroke preventability, and determined the cumulative burden of risk factors that necessitate optimization following the ischemic insult.
Source: Journal of Stroke and Cerebrovascular Diseases - April 29, 2020 Category: Neurology Authors: Irem Erkent, Mehmet Akif Topcuoglu, Mine Hayriye Sorgun, Hale Zeynep Batur Caglayan, Canan Togay Isikay, Bijen Nazliel, Ethem Murat Arsava Source Type: research

Assessing executive function following the early stage of mild Ischemic stroke with three brief screening tests
Stroke, as the main disabling disease around the world, brings heavy economic and social burden to all countries, including China, an aging country.1 Post-stroke cognitive impairment (PSCI), one of the most “invisible disabilities”, is common among stroke survivors and can have a significant effect upon a patient's quality of life.2,3 Among stroke patients, the prevalence of PSCI is 81.4% and cognitive impairment in post-stroke patients manifests in various cognitive domains, with executive functio n being the most common.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Kai Shao, Wei Wang, Shang-Zun Guo, Fang-Ming Dong, Yi-Ming Yang, Zhong-Min Zhao, Yan-Li Jia, Jian-Hua Wang Source Type: research

Combined polymorphisms in genes encoding the inflammasome components NLRP3 and CARD8 confer risk of ischemic stroke in men
Stroke is a common medical emergency with high mortality. There are two types of stroke, namely, hemorrhagic stroke and ischemic stroke (IS), and 85 –90% of stroke cases are ischemic. Studies have confirmed that the nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome may be involved in activating the inflammation and pathophysiology of atherosclerosis as well as in mediating inflammatory injury during cerebral ischemia .1
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Jie Lv, Xiaoshan Jiang, Jing Zhang, Xianghui Peng, Hongmei Lin Source Type: research

Thrombolytic therapy in ischemic stroke patients with pre-stroke depression in the telestroke vs non-telestroke
This study aims to examine clinical risk factors associated with inclusion or exclusion for rtPA in acute ischemic stroke populations with pre-stroke depression in the telestroke versus a non-telestroke setting.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Robyn Moraney, Nicolas Poupore, Rachel Shugart, Mandy Tate, Ashley Snell, Katherine Brown, Thomas I. Nathaniel Source Type: research

Predictors of Recurrent Ischemic Stroke in Obese Patients With Type 2 Diabetes Mellitus: A Population-based Study
Each year, approximately 0.8 million people are estimated to experience a new or recurrent stroke, according to the 2019 report of the American Heart Association.1 In Malaysia, stroke is the third leading cause of death after ischemic heart disease (IHD) and pneumonia.2 Both obesity and diabetes are considered as the established independent risk factors for ischemic stroke.3 Type 2 diabetes mellitus (T2DM) was also found to be associated with an increase in all-cause as well as cardiovascular mortality following the stroke,4,5 and in a meta-analysis of 18 studies, patients with diabetes had a higher stroke recurrence as co...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Orwa Albitar, Sabariah Noor Harun, Nur Ezzati Abidin, Balamurugan Tangiisuran, Hadzliana Zainal, Irene Looi, Khairul Azmi Ibrahim, Norsima Nazifah Sidek, Keat Wei Loo, Keng Yee Lee, Zariah Abdul Aziz, Siti Maisharah Sheikh Ghadzi Source Type: research