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Influence of Amyloid-{beta} on Cognitive Decline After Stroke/Transient Ischemic Attack: Three-Year Longitudinal Study Clinical Sciences
Conclusions— Compared with subjects without Alzheimer’s disease–like Aβ deposition, those with Aβ deposition experienced a more severe and rapid cognitive decline over 3 years after stroke/transient ischemic attack. Aβ was associated with changes in multiple cognitive domains.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Liu, W., Wong, A., Au, L., Yang, J., Wang, Z., Leung, E. Y. L., Chen, S., Ho, C. L., Mok, V. C. T. Tags: Behavioral Changes and Stroke, PET and SPECT Clinical Sciences Source Type: research

Integrin {alpha}4 Overexpression on Rat Mesenchymal Stem Cells Enhances Transmigration and Reduces Cerebral Embolism After Intracarotid Inȷection Brief Report
Conclusions—ITGA4 overexpression on MSCs enhances transendothelial migration in vitro, but not in vivo, although it improves safety after intracarotid transplantation into stroke rats.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Li–li Cui, Franziska Nitzsche, Evgeny Pryazhnikov, Marina Tibeykina, Laura Tolppanen, Jussi Rytkonen, Tuulia Huhtala, Jing–wei Mu, Leonard Khiroug, Johannes Boltze, Jukka Jolkkonen Tags: Cell Therapy, Translational Studies, Ischemic Stroke Brief Reports Source Type: research

Effects of Noninvasive Brain Stimulation on Language Networks and Recovery in Early Poststroke Aphasia Clinical Sciences
Conclusions— Ten sessions of inhibitory rTMS over the right posterior inferior frontal gyrus, in combination with speech and language therapy, significantly improve language recovery in subacute ischemic stroke and favor recruitment of left-hemispheric language networks.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Thiel, A., Hartmann, A., Rubi-Fessen, I., Anglade, C., Kracht, L., Weiduschat, N., Kessler, J., Rommel, T., Heiss, W.-D. Tags: Behavioral Changes and Stroke, PET and SPECT, Rehabilitation, Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Amyloid Burden, Neuroinflammation, and Links to Cognitive Decline After Ischemic Stroke Topical Reviews
Source: Stroke - August 25, 2014 Category: Neurology Authors: Thiel, A., Cechetto, D. F., Heiss, W.-D., Hachinski, V., Whitehead, S. N. Tags: Behavioral Changes and Stroke, PET and SPECT, Neuroprotectors Topical Reviews Source Type: research

Combined 18F-FDG PET-CT and DCE-MRI to Assess Inflammation and Microvascularization in Atherosclerotic Plaques Brief Reports
Conclusions— There is a weak but significant positive correlation between inflammation on positron emission tomography/computed tomography and neovascularization as assessed with dynamic contrast–enhanced-MRI. Future studies should investigate which imaging modality has the highest predictive value for recurrent stroke, as these are not interchangeable. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00451529.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Truijman, M. T. B., Kwee, R. M., van Hoof, R. H. M., Hermeling, E., van Oostenbrugge, R. J., Mess, W. H., Backes, W. H., Daemen, M. J., Bucerius, J., Wildberger, J. E., Kooi, M. E. Tags: Imaging, Carotid Stenosis, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT Brief Reports Source Type: research

Monitoring Neuroprotective Effects Using Positron Emission Tomography With 11CITMM, a Radiotracer for Metabotropic Glutamate 1 Receptor Basic Sciences
Conclusions— [11C]ITMM-PET may be a useful technique for characterizing the change in mGlu1 level during the occurrence and progression of neuronal damage and for evaluating the neuroprotective effects of drugs after ischemia.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Yui, J., Xie, L., Fujinaga, M., Yamasaki, T., Hatori, A., Kumata, K., Nengaki, N., Zhang, M.-R. Tags: PET and SPECT Basic Sciences Source Type: research

Increase in 18F-Fluoroacetate Uptake in Patients With Chronic Hemodynamic Cerebral Ischemia Brief Reports
Conclusions— In patients with atherosclerotic internal carotid artery or middle cerebral artery disease, 18F-FACE uptake is increased in the noninfarcted cerebral cortex with chronic hemodynamic ischemia characterized by misery perfusion with decreased oxygen metabolism. Increased 18F-FACE uptake may indicate the cortical regions that are at particular risk for ischemic damage.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Yamauchi, H., Kagawa, S., Kishibe, Y., Takahashi, M., Nishii, R., Mizuma, H., Takahashi, K., Onoe, H., Higashi, T. Tags: PET and SPECT Brief Reports Source Type: research