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Source: Neurological Sciences
Condition: Ischemic Stroke

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Total 240 results found since Jan 2013.

Venous thromboembolism prevention with low molecular weight heparin may reduce hemorrhagic transformation in acute ischemic stroke
ConclusionsThis retrospective study suggests that SHPD may play a protective role in HT appearance and evolution, which requires verification by a randomized clinical trial.
Source: Neurological Sciences - March 23, 2020 Category: Neurology Source Type: research

Dynamic increase in neutrophil levels predicts parenchymal hemorrhage and function outcome of ischemic stroke with r-tPA thrombolysis
ConclusionsDynamic increase in neutrophil and NLR after stroke may predict PH and 3-month poor outcome in AIS patients receiving r-tPA treatment. Therefore, neutrophil and NLR may serve as activity markers for PH and 3-month poor prognosis in AIS patients with intravenous thrombolysis.
Source: Neurological Sciences - March 15, 2020 Category: Neurology Source Type: research

The elevation of S100B and downregulation of circulating miR-602 in the sera of ischemic stroke (IS) patients: the emergence of novel diagnostic and prognostic markers
AbstractIschemic stroke (IS) is a major cause of mortality and disability. However, no reliable prognostic or diagnostic biomarker has been utilized to date. Here, we have evaluated the serum S100B concentration and miR-602 expression as potential biomarkers for IS. Fifty-two IS patients and 52 age- and sex-matched healthy volunteers were enrolled. Blood samples were collected from all patients at the time of admission, 24 and 48  h later, at the time of discharge, and 3 months later. Real-time (RT) PCR was used to measure the serum level of miR602. We also measured the serum concentration of S100B using ELISA. As compar...
Source: Neurological Sciences - March 11, 2020 Category: Neurology Source Type: research

The effectiveness of various cytotherapeutic strategies for the treatment of ischemic stroke: a Bayesian network meta-analysis of randomized controlled trials
ConclusionsIn the subacute stage, the intra-arterial injection of NCs or ALDH cells improves patients ’ activity of daily living. Additionally, CD34+ cells through intracerebral injection had an advantage in the recovery of injured nerve function even in the chronic stage. Intravenous injection of MSCs or EPCs is a safety delivery route that can reduce mortality and SAE onset. However, further clinical studies are still needed to confirm these results.
Source: Neurological Sciences - March 3, 2020 Category: Neurology Source Type: research

The influence of statins on the risk of post-stroke epilepsy
ConclusionAdequate treatment with statins after stroke may lower the risk of PSE.
Source: Neurological Sciences - February 20, 2020 Category: Neurology Source Type: research

Value of thrombus imaging in predicting the outcomes of patients with large-vessel occlusive strokes after endovascular therapy
ConclusionImaging of thrombus can be used as an aseessment tool to predict the outcomes and it needs further studies in the future.
Source: Neurological Sciences - February 20, 2020 Category: Neurology Source Type: research

Low TSH level predicts a poor clinical outcome in patients with anterior circulation ischemic stroke after endovascular thrombectomy
ConclusionA lower TSH value upon admission may predict an unfavorable functional outcome in AIS patients after EVT, but thyroid hormone levels have no bearing on the risk of HT.
Source: Neurological Sciences - February 12, 2020 Category: Neurology Source Type: research

A case of growing dural sinus malformation with associated developmental venous anomaly presenting like transient ischemic attack progressing into stroke
Source: Neurological Sciences - January 31, 2020 Category: Neurology Source Type: research

Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology
ConclusionHyperintensities could serve as a diagnostic and prognostic imaging biomarker for patients, presenting with mild acute focal neurology, warranting application of automated quantification methods. However, larger cohorts are required to provide a definitive answer especially as this is a heterogenous group of patients.
Source: Neurological Sciences - January 22, 2020 Category: Neurology Source Type: research

Why we fail: mechanisms and co-factors of unsuccessful thrombectomy in acute ischemic stroke
ConclusionIn 20% of failing MT, thrombus cannot be reached/passed. Direct carotid puncture or surgical arterial access could be considered in these cases.In 80% of failing interventions, thrombus can be passed with the device, but the occluded vessel cannot be recanalized. Rescue techniques can be an option. Development of new devices and techniques is necessary to improve recanalization rates. Assessment of pre-existing illness could sensitize for occurring complications.
Source: Neurological Sciences - January 22, 2020 Category: Neurology Source Type: research

Decreased visible deep medullary veins is a novel imaging marker for cerebral small vessel disease
ConclusionMultifactorial association between DMV scale and epidemiological, radiological contributors of aCSVD suggests DMV ’s involved pathomechanism may participate in aCSVD development. Attach importance to DMV radiological profile in aCSVD will provide more neuroimaging information for diagnosis and prognosis.
Source: Neurological Sciences - January 17, 2020 Category: Neurology Source Type: research

Insulin resistance is an independent risk factor for early neurological deterioration in non-diabetic patients with acute ischemic stroke
ConclusionThis study strongly suggests that IR is probably an independent risk factor for END in non-diabetic patients with acute ischemic stroke.
Source: Neurological Sciences - January 13, 2020 Category: Neurology Source Type: research

Utility of a scoring system for differentiating cancer-associated stroke from cryptogenic stroke in patients with cancer
ConclusionTrousseau scores simply and clearly identify CAS.
Source: Neurological Sciences - January 6, 2020 Category: Neurology Source Type: research

The role of carotid stenosis ultrasound scale in the prediction of ischemic stroke
ConclusionsThe novel CASUS can better reflect the level of cerebral reperfusion in patients with ischemic stroke and can better predict the occurrence of cardiovascular and cerebrovascular diseases.
Source: Neurological Sciences - January 2, 2020 Category: Neurology Source Type: research

Bilirubin: a novel predictor of hemorrhagic transformation and symptomatic intracranial hemorrhage after mechanical thrombectomy
ConclusionsElevated admission bilirubin is an independent predictor of HT and sICH in AIS patients treated with MT.
Source: Neurological Sciences - December 10, 2019 Category: Neurology Source Type: research