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Source: Neurological Research
Condition: Ischemic Stroke
Education: Study
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Total 301 results found since Jan 2013.
Association between polyvascular atherosclerosis and estimated glomerular filtration rate in patients with ischaemic stroke: data analysis of the patients in the Chinese National Stroke Registry.
This study evaluated the prevalence of chronic kidney disease (CKD) in ischemic stroke (IS) patients with polyvascular disease (PolyVD) and analysed the relationship between PolyVD and estimated glomerular filtration rate (eGFR) in IS patients.
METHODS: Data from 9152 consecutive IS patients from the China National Stroke Registry were analysed. PolyVD was defined as patients with IS and coronary artery disease (CAD) and/or peripheral arterial disease (PAD). Chronic kidney disease was defined as eGFR < 60 mL/minute/1.73 m(2).The prevalence of CKD in IS patients with PolyVD was calculated. Logistic regression w...
Source: Neurological Research - April 22, 2015 Category: Neurology Tags: Neurol Res Source Type: research
C-reactive protein gene polymorphisms and gene-environment interactions in ischaemic stroke.
Authors: Chen Z, Yu D, Xu ZW, Li SS, Li XF, Li J, Yang X
Abstract
Ischaemic stroke is a heterogeneous, multifactorial disease caused by the combination of certain risk factors and genetic factors. Several single nucleotide polymorphisms (SNPs) of C-reactive protein (CRP) have been reported to be associated with serum CRP levels. However, genetic association studies have produced conflicting results regarding the association between these SNPs and ischaemic stroke. In this paper, we conducted a population-based case-control study to determine whether two SNPs of CRP (rs1800947 and rs3093059) are associated with isch...
Source: Neurological Research - May 26, 2015 Category: Neurology Tags: Neurol Res Source Type: research
Association study between C-reactive protein polymorphisms and ischaemic stroke.
CONCLUSIONS: There is no association between rs1130864 or rs3093059 and ischaemic stroke in Chinese Han population.
PMID: 26039816 [PubMed - as supplied by publisher]
Source: Neurological Research - June 4, 2015 Category: Neurology Tags: Neurol Res Source Type: research
High nonfasting triglyceride concentrations predict good outcome following acute ischaemic stroke.
DISCUSSION: Higher fasting and nonfasting serum TG concentrations predicted good poststroke outcome independently of other prognostic factors.
PMID: 28683603 [PubMed - as supplied by publisher]
Source: Neurological Research - July 9, 2017 Category: Neurology Tags: Neurol Res Source Type: research
Association of hemoglobin glycation index with outcomes of acute ischemic stroke in type 2 diabetic patients.
Conclusion Both low HGI and high HGI was associated with an increased risk of poor prognosis in diabetic patients with ischemic stroke, compared with moderate HGI.
PMID: 29560815 [PubMed - as supplied by publisher]
Source: Neurological Research - March 23, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Lp-PLA2 as a risk factor of early neurological deterioration in acute ischemic stroke with TOAST type of large arterial atherosclerosis.
Authors: Wang Y, Hu S, Ren L, Lei Z, Lan T, Cai J, Li C
Abstract
INTRODUCTION: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a well-known risk factor of atherosclerotic vascular diseases. Nevertheless, its role in the acute phase of ischemic stroke is still unclear. The aim of this study is to identify the relationship between Lp-PLA2 levels and early neurological deterioration (END) in acute ischemic stroke patients with Trial of Org 10 172 in Acute Stroke Treatment (TOAST) subtype of large arterial atherosclerosis (LAA).
METHODS: We enrolled Chinese patients with first ever acute ischemic stroke admitt...
Source: Neurological Research - October 10, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Factors associated with medication persistence among ischemic stroke patients: a systematic review.
Conclusions: Stroke patients' medication persistence decreases over time, and persistence on antiplatelets, anticoagulants, and statin was poor. Several factors were associated with medication persistence, and these factors should be considered in future secondary preventative strategies.
PMID: 32321382 [PubMed - as supplied by publisher]
Source: Neurological Research - April 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research
Screening for cognitive impairment with the montreal cognitive assessment at six months after stroke and transient ischemic attack.
CONCLUSION: The MoCA-Beijing cutoff score for differentiating CI from NCI after stroke and TIA at six months was at 24/25, and it is important for routine clinical practice.
PMID: 32967577 [PubMed - as supplied by publisher]
Source: Neurological Research - September 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research
Association of inflammatory and platelet volume markers with clinical outcome in patients with anterior circulation ischaemic stroke after endovascular thrombectomy.
Conclusions: MPV, PDW, and MPV/PC are associated with stroke severity. Higher NLR levels upon admission may predict unfavorable functional outcomes in patients with AIS after undergoing EVT.Abbreviations ACA: anterior cerebral artery; AIS: acute ischemic stroke; ASPECTS: alberta stroke program early CT score; BMI: body mass index; DBP: diastolic blood pressure; END: early neurological deterioration; EVT: endovascular thrombectomy; hs-CRP: high-sensitivity C-reactive protein; HT: hemorrhagic transformation; ICA: internal carotid artery; IL-6: interleukin-6; IS: ischemic progression; LAA: Large-Artery Atherosclerosis; MCA: m...
Source: Neurological Research - January 8, 2021 Category: Neurology Tags: Neurol Res Source Type: research
Application of the P300 potential in cognitive impairment assessments after transient ischemic attack or minor stroke.
Conclusions The P300 latency delay can be used to detect cognitive impairments in patients after TIA/minor stroke and the P300-Fz latency is more sensitive for diagnosing cognitiveimpairments in TIA/minor stroke patients.
PMID: 33443462 [PubMed - as supplied by publisher]
Source: Neurological Research - January 15, 2021 Category: Neurology Tags: Neurol Res Source Type: research
Obesity in acute ischaemic stroke patients treated with intravenous thrombolysis therapy
Conclusions: Obesity may be related to long-term prognosis of large group of AIS patients treated with IVT. It depends on the scale of clinical study samples, follow-up time, and evaluation criteria.PMID:34112057 | DOI:10.1080/01616412.2021.1939486
Source: Neurological Research - June 11, 2021 Category: Neurology Authors: Hongmin Li Suliman Khan Rabeea Siddique Qian Bai Yang Liu Ruiyi Zhang Yan Zhang V Wee Yong Mengzhou Xue Source Type: research
No rebound effect after a course of clopidogrel in patients with acute TIA or minor stroke
CONCLUSIONS: No rebound increase in the risk of ischemic stroke and composite events was found during the 90 days after discontinuation of clopidogrel therapy in patients with TIA or minor stroke in the CHANCE trial.TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00979589.PMID:35695332 | DOI:10.1080/01616412.2022.2075660
Source: Neurological Research - June 13, 2022 Category: Neurology Authors: Xinmiao Zhang Jing Jing Xingquan Zhao Liping Liu Anxin Wang Yuesong Pan David Wang S Claiborne Johnston Yilong Wang Yongjun Wang Xia Meng Source Type: research
