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Safety and Hemodynamic Profile of Propofol and Dexmedetomidine Anesthesia during Intra-arterial Acute Stroke Therapy
There is limited data on the safety, hemodynamic profile, and outcome of patients undergoing intra-arterial therapy (IAT) for acute ischemic stroke (AIS) under sedation with dexmedetomidine (DEX) versus propofol (PROP).
Source: Journal of Stroke and Cerebrovascular Diseases - July 28, 2015 Category: Neurology Authors: Seby John, Jaspreet Somal, Umera Thebo, Muhammad S. Hussain, Ehab Farag, Suzanne Dupler, Joao Gomes Source Type: research

Update on anesthetic neuroprotection
Purpose of review: Perioperative cerebral injury can result in a wide range of clinical consequences from subtle cognitive changes to devastating or fatal strokes. Although the overall incidence of perioperative stroke is low, the large and growing number of aging patients undergoing surgery and anesthesia is placing an increasing number of vulnerable patients at risk. The purpose of this review is to evaluate recent evidence concerning the use of pharmacological and nonpharmacological strategies to protect against perioperative cerebral injury. Recent findings: Although a growing body of preclinical literature suggests th...
Source: Current Opinion in Anaesthesiology - July 3, 2015 Category: Anesthesiology Tags: DRUGS IN ANESTHESIA: Edited by Tong J. Gan Source Type: research

Methodology of Motor Evoked Potentials in a Rabbit Model
This study provides the basis for a reproducible model of SCI to be used for novel therapeutic drug development.
Source: Translational Stroke Research - May 20, 2015 Category: Neurology Source Type: research

Early neurological complications after transcatheter closure of atrial septal defect with nitinol wire mesh occluder.
Abstract Atrial septal defect (ASD) was closed percutaneously in an 18-year-old boy with a 27 mm nitinol wire mesh occluder according to standard procedures. Three hours after the procedure, he presented anxiety attacks, aggression, a vacant stare and a verbal/speaking disorder. Small ischaemic stroke localised in the right temporal/parietal region of the central nervous system was confirmed by computed tomography examination. Activated partial thromboplastin time was then 54 s despite continuous heparin infusion. Heparin dose was increased and symptomatic treatment was introduced (mannitol, furosemide, propofol, ...
Source: Polish Heart Journal - September 27, 2013 Category: Cardiology Authors: Heredia JD, Szkutnik M, Fiszer R, Zyła-Frycz M, Białkowski J Tags: Kardiol Pol Source Type: research

Endovascular treatment of intracranial arteriovenous malformation with n-butyl cyanoacrylate. Working methods and experience in 58 cases.
CONCLUSIONS: The rates of total occlusion and of morbidity and mortality in the series are in the internationally described ranges. The implementation of intranidal closings with 20-30% devascularization per session and the use of post-embolization hypotension after the haemorrhage complications described resulted in the total absence of haemorrhagic complications. PMID: 23566543 [PubMed - in process]
Source: Neurocirugia - May 1, 2013 Category: Neurosurgery Authors: Jordan González JA, Llibre Guerra JC, Prince López JA, Vázquez Luna F, Rodríguez Ramos RM, Ugarte Suarez JC Tags: Neurocirugia (Astur) Source Type: research

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