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Epidemiology of stroke in the last decade: a systematic review
CONCLUSION: There are few studies that analyse the incidence of CVD and even fewer that analyse its evolution. The overall median remains high, although the figures are heterogeneous across studies. Worldwide the trend is towards its decrease, and there are geographical areas, especially in Asia, with an alarming upward trend.PMID:34676530 | DOI:10.33588/rn.7309.2021138
Source: Revista de Neurologia - October 22, 2021 Category: Neurology Authors: F Purroy N Montal à Source Type: research

Acute Treatment of Ischemic Stroke
This article outlines the evidence to support intravenous thrombolysis with alteplase and tenecteplase, thrombolysis in the setting of DWI/flair mismatch, endovascular treatment in the 6-hour and 6- to 24-hour window, and the use of telemedicine in acute stroke. Current controversies and ongoing trials within endovascular treatment are also detailed. Case presentations are included to provide clinical context and the application of data to practice.
Source: Neurologic Clinics - November 17, 2021 Category: Neurology Authors: Stephanie Lyden, Jana Wold Source Type: research

P-029 Impact of in-hospital delirium on outcomes of acute ischemic stroke
ConclusionsDelirium complicates ~3.5% of AIS admissions, and is associated with increased risk of in-hospital death, longer stay, higher charges and decrease in likelihood of home discharge.Disclosures D. Pujara: None. H. Kamal: None. O. Mir: None. S. Reddy: None. K. Parsha: None. S. Patil: None. B. Gogia: None. P. Rai: None. C. Sitton: None. M. Chen: None. M. Abraham: None. M. Hussain: None. A. Hassan: None. A. Sarraj: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Pujara, D., Kamal, H., Mir, O., Reddy, S., Parsha, K., Patil, S., Gogia, B., Rai, P., Sitton, C., Chen, M., Abraham, M., Hussain, M., Hassan, A., Sarraj, A. Tags: Oral poster abstracts Source Type: research

Intravenous Thrombolytics in the Treatment of Acute Ischemic Stroke
AbstractPurpose of ReviewTo review the current evidence and ongoing clinical trials evaluating the efficacy and safety of tenecteplase (TNK), an alternative tissue plasminogen activator (tPA), in the acute management of arterial ischemic stroke (AIS). To date, alteplase is the only tPA approved by the United States FDA for use in AIS.Recent FindingsThere have been multiple phase two and three trials investigating the safety and efficacy of TNK in AIS. In patients with AIS due to large vessel occlusion, one randomized controlled trial demonstrated superiority of TNK for vessel recanalization rates and long-term functional o...
Source: Current Treatment Options in Cardiovascular Medicine - January 2, 2023 Category: Cardiology Source Type: research

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