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Single-step direct drug provocation testing is safe for de-labelling selected "non-low-risk" penicillin allergy labels
CONCLUSION: In our cohort, direct single-step DPT was safe with only 6 patients with "non-low risk" allergy experiencing benign reactions. We hope further study can be performed into single-step direct DPT for interrogating "non-low risk" penicillin allergy labels.PMID:33865989 | DOI:10.1016/j.anai.2021.04.008
Source: Annals of Allergy, Asthma and Immunology - April 18, 2021 Category: Allergy & Immunology Authors: Jamma Li Vera Cvetanovski B Nursing Suran Fernando Source Type: research

Trends in U.S. hospitalizations for anaphylaxis among infants and toddlers: 2006-2015.
CONCLUSION: Anaphylaxis hospitalizations among infants and toddlers in the US were stable from 2006-2015, while hospitalizations among older children were rising. Future research should focus on the trends in disease prevalence and healthcare utilization in the understudied population of infants and toddlers. PMID: 32911059 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 6, 2020 Category: Allergy & Immunology Authors: Robinson LB, Arroyo AC, Faridi MK, Rudders SA, Camargo CA Tags: Ann Allergy Asthma Immunol Source Type: research

Cholinergic Urticaria with Anaphylaxis: An Underrecognized Clinical Entity
Conclusions Anaphylaxis due to cholinergic triggers is underreported, with only several case reports in the literature. Reactions are multisystem with cutaneous, upper and lower airway, and cardiovascular involvement in most patients. Manifestations may be life-threatening, and reactions are often severe.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 8, 2016 Category: Allergy & Immunology Source Type: research

Biphasic reactions in patients with anaphylaxis treated with corticosteroids.
CONCLUSION: The incidence of biphasic reactions was 2.2% in patients treated with corticosteroids and those with a history of drug anaphylaxis were at greater risk. PMID: 26276313 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - August 11, 2015 Category: Allergy & Immunology Authors: Ko BS, Kim WY, Ryoo SM, Ahn S, Sohn CH, Seo DW, Lee YS, Lim KS, Kim TB Tags: Ann Allergy Asthma Immunol Source Type: research