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Outcomes Among Clopidogrel, Prasugrel, and Ticagrelor in ST-Elevation Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention From the TOTAL Trial
ConclusionsIn this observational analysis of STEMI patients who underwent primary percutaneous coronary intervention, ticagrelor was associated with improved outcomes compared with clopidogrel and prasugrel. An appropriately powered randomized trial is needed to confirm these findings.RésuméContexteIl n’existe pas d’analyse robuste comparant les inhibiteurs P2Y12 à prise orale (clopidogrel, prasugrel et ticagrélor) chez les patients ayant subi un infarctus du myocarde avec élévation du segment ST (STEMI) traités par une intervention coronaire percutanée (ICP) primaire. Nous avons entrepris d’évaluer les rés...
Source: Canadian Journal of Cardiology - October 9, 2019 Category: Cardiology Source Type: research

Outcomes Among Clopidogrel, Prasugrel, And Ticagrelor In Stemi Patients Undergoing Primary Percutaneous Coronary Intervention From The Total Trial
ConclusionsIn this observational analysis of STEMI patients undergoing PPCI, ticagrelor was associated with improved outcomes compared to clopidogrel and prasugrel. An appropriately powered randomized trial is needed to confirm these findings.
Source: Canadian Journal of Cardiology - May 8, 2019 Category: Cardiology Source Type: research

Modality selection for the revascularization of left main disease
Publication date: Available online 15 December 2018Source: Canadian Journal of CardiologyAuthor(s): Derrick Y. Tam, Faisal Bakaeen, Dmitriy N. Feldman, Philippe Kolh, Gaetano Antonio Lanza, Marc Ruel, Raffaele Piccolo, Stephen E. Fremes, Mario FL. GaudinoAbstractThe management of severe left main (LM) disease remains controversial and continues to evolve as new evidence emerges. Patient selection for CABG or PCI relies on both predicting mortality with CABG from clinical characteristics using the Society of Thoracic Surgeons risk score and anatomical complexity using the SYNTAX score. LM stenting techniques continue to evo...
Source: Canadian Journal of Cardiology - December 15, 2018 Category: Cardiology Source Type: research

Transcatheter vs Surgical Aortic Valve Replacement for Aortic Stenosis in Low-Intermediate Risk Patients: A Meta-analysis
Conclusions Although there was no difference in 30-day and late mortality, the rate of complications differed between TAVR and SAVR in the low-intermediate surgical risk population.
Source: Canadian Journal of Cardiology - August 25, 2017 Category: Cardiology Source Type: research

Transcatheter Versus Surgical Aortic Valve Replacement for Aortic Stenosis in Low-Intermediate Risk Patients: A Meta-Analysis
Conclusions While there was no difference in 30-day and late mortality, the rate of complications differed between TAVR and SAVR in the low-intermediate surgical risk population. Teaser In this meta-analysis, there was no difference in 30-day and median 1.5-year mortality outcomes between TAVR and SAVR. However, there was a higher incidence of aortic insufficiency, vascular complications and permanent pacemaker implantation after TAVR compared to SAVR and a higher incidence of atrial fibrillation, acute kidney injury, major bleeding and cardiogenic shock after SAVR compared to TAVR.
Source: Canadian Journal of Cardiology - June 16, 2017 Category: Cardiology Source Type: research