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The Effects of Mesenchymal Stem Cells on the Gene Expression of TGF-beta and IFN-gamma in Patients with Rheumatoid Arthritis
This study aimed to evaluate the expression of genes encoding interleukin (IL)4 and IL10, as well as interferon-gamma (IFNG) and transforming growth factor beta (TGFB1) in refractory RA patients following intravenous injection of autologous bone marrow-derived MSCs (BM-MSCs). This study was registered in Iranian Registry of Clinical Trials (IRCT) (2015102824760N1) and ClinicalTrials.gov (identifier: NCT03333681). Blood samples were taken from 13 patients before and 1 and 6 months after the MSC injection to evaluate the clinical manifestations, paraclinical factors, and expression of IL4, IL10, IFNG, and TGFB1 genes employi...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 27, 2023 Category: Allergy & Immunology Authors: Maryam Rahimi Khorashad Mohsen Ghoryani Arezoo Gowhari Shabgah Zhaleh Shariati-Sarabi Jalil Tavakkol Afshari Mojgan Mohammadi Source Type: research

Investigation of the effect of oral selenium on the reduction of clinical symptoms and joint pain in patients with rheumatoid arthritis in the Iranian population
This article is protected by copyright. All rights reserved.PMID:37306592 | DOI:10.1002/jcph.2292
Source: The Journal of Clinical Pharmacology - June 12, 2023 Category: Drugs & Pharmacology Authors: Maryam Mehrpooya Mahnam Majmasanaye Fatemeh Faramarzi Azadeh Eshraghi Foroozan Faress Source Type: research

Adherence to treatment and associated factors in rheumatoid arthritis patients: a cross-sectional study from Iran
Reumatismo. 2023 May 8;75(1). doi: 10.4081/reumatismo.2023.1540.ABSTRACTThe aim of this study is to evaluate adherence to treatment and its related risk factors among a sample of rheumatoid arthritis patients (RA) attending the rheumatology outpatient clinic of Kermanshah university of medical sciences. In this cross-sectional study, RA patients were asked to complete the Morisky questionnaire and 19-item compliance questionnaire for rheumatology (CQR). Patients were divided into two groups: adherent and non-adherent to treatment, based on the CQR questionnaire results. Demographic and clinical characteristics (age, sex, m...
Source: Reumatismo - May 8, 2023 Category: Rheumatology Authors: D Mohamadzadeh S Assar M Pournazari P Soufivand M S Soleymani Source Type: research

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