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Total 157 results found since Jan 2013.
Unraveling crime scenes strand by strand: the forensic odyssey of Bruce Budowle
Biotechniques. 2023 Aug 25. doi: 10.2144/btn-2023-0069. Online ahead of print.ABSTRACTBruce Budowle speaks to Ashling Cannon, Journal Development Editor for BioTechniques, about advancements & challenges in forensic science. Budowle completed his doctorate in genetics at Virginia Tech (VA, USA) formally known as Virginia Polytechnic Institute and State University. He then went on to complete a postdoctoral fellowship at the University of Alabama at Birmingham (AL, USA) to study genetic risk factors for acute lymphocytic leukemia, diabetes and melanoma. Budowle was early in his career and hadn't spent much time in foren...
Source: BioTechniques - August 25, 2023 Category: Biotechnology Authors: Bruce Budowle Source Type: research
Fight Aging! Newsletter, July 24th 2023
In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells.
Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Ligature placement caused progressive periodontal disease and bone resorption that was already significant on day 1 post-ligation and continued to increase until day 30. The severity of periodontal disease increased the frequency of activated microglia in the brains on day 30 by 36...
Source: Fight Aging! - July 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Formation and Implementation of Public Health Policy Toward Salt Reduction in Food Consumption
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231180164. doi: 10.1177/21501319231180164.ABSTRACTThis action research aimed to study the processes of public health policy toward salt reduction in food consumption. The processes were divided into 3 cycles as follows: 1) Public health policy formation; 2) Development of the policy to reduce dietary salt; and 3) Evaluation of the efficiency of the policy. Participants from the first group involved in policy formation; and a total number of 320 participants were recruited in the study with the criteria of a) age 18 years and above, b) having hypertension or at risk of h...
Source: Primary Care - June 12, 2023 Category: Primary Care Authors: Paralee Opasanant Panpimol Sukwong Source Type: research
Preventing Genetic Testing Fraud: 5 Actions for Health Plans
The following is a guest article by Erin Rutzler, Vice President of Fraud, Waste, and Abuse at Cotiviti
In Delaware, more than 250 Medicare patients underwent unnecessary genetic testing based on telehealth consultations that often lasted less than two minutes—costing Medicare thousands of dollars per patient. Meanwhile, an emerging scheme for fraudulent and unnecessary cardiovascular and cancer genetic testing allegedly resulted in $174 million in false and fraudulent Medicare claims.
These are just two examples of what the Healthcare Fraud Prevention Partnership describes as a surge in fraud, waste and abuse associated...
Source: EMR and HIPAA - May 5, 2023 Category: Information Technology Authors: Guest Author Tags: Administration Genomics-Precision Medicine Health IT Company Healthcare IT Regulations Revenue Cycle Management Cotiviti CPT Codes Erin Rutzler Fraud Waste and Abuse FWA Genetic Testing Genetic Testing Fraud Healthcare Fraud Prev Source Type: blogs
A comprehensive review on celastrol, triptolide and triptonide: Insights on their pharmacological activity, toxicity, combination therapy, new dosage form and novel drug delivery routes
Biomed Pharmacother. 2023 Apr 13;162:114705. doi: 10.1016/j.biopha.2023.114705. Online ahead of print.ABSTRACTCelastrol, triptolide and triptonide are the most significant active ingredients of Tripterygium wilfordii Hook F (TWHF). In 2007, the 'Cell' journal ranked celastrol, triptolide, artemisinin, capsaicin and curcumin as the five natural drugs that can be developed into modern medicinal compounds. In this review, we collected relevant data from the Web of Science, PubMed and China Knowledge Resource Integrated databases. Some information was also acquired from government reports and conference papers. Celastrol, trip...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 16, 2023 Category: Drugs & Pharmacology Authors: Jing Song Guan-Nan He Long Dai Source Type: research
Metformin, A Biological and Synthetic Overview
Bioorg Med Chem Lett. 2023 Mar 16:129241. doi: 10.1016/j.bmcl.2023.129241. Online ahead of print.ABSTRACTMetformin is the most widely known anti-hyperglycemic, officially acquired by the USA government in 1995 and in 2001 it became the most prescribed treatment for type II diabetes. But how did it become the must-use drug for this disease in such a short period of time? it all started with traditional medicine, by using a plant known as "goat's rue" for the reduction of blood glucose levels. Its use arose in 1918 and evolved to the metformin synthesis in laboratories a couple of years later, using very rudimentary methods ...
Source: Bioorganic and Medicinal Chemistry Letters - March 18, 2023 Category: Chemistry Authors: Edson D Hern ández-Velázquez Clara Alba-Betancourt Ángel J Alonso-Castro Rafael Ortiz-Alvarado Jes ús A López Victor Meza-Carmen C ésar R Solorio-Alvarado Source Type: research
Metformin, a biological and synthetic overview
Bioorg Med Chem Lett. 2023 Mar 16;86:129241. doi: 10.1016/j.bmcl.2023.129241. Online ahead of print.ABSTRACTMetformin is the most widely known anti-hyperglycemic, officially acquired by the USA government in 1995 and in 2001 it became the most prescribed treatment for type II diabetes. But how did it become the must-use drug for this disease in such a short period of time? it all started with traditional medicine, by using a plant known as "goat's rue" for the reduction of blood glucose levels. Its use arose in 1918 and evolved to the metformin synthesis in laboratories a couple of years later, using very rudimentary metho...
Source: Bioorganic and Medicinal Chemistry Letters - March 18, 2023 Category: Chemistry Authors: Edson D Hern ández-Velázquez Clara Alba-Betancourt Ángel J Alonso-Castro Rafael Ortiz-Alvarado Jes ús A López Victor Meza-Carmen C ésar R Solorio-Alvarado Source Type: research
