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Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage. Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored ...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news

Fool Me Once: An Uncommon Presentation of PE
​BY FREDDIE IRIZARRY-DELGADO; VAROON KAKAIYA; & AHMED RAZIUDDIN, MDAn 86-year-old African-American woman was brought to the ED by her daughter after two days of nutritional neglect, abdominal pain, and altered mental status. Her daughter said her mother felt lightheaded, appeared dehydrated, and vomited nonbilious watery fluid once. The patient had a history of diabetes mellitus type 2, DVT/PE, dementia, and early signs of parkinsonism.Her vital signs were remarkable only for tachypnea (24 bpm). Her troponin I was markedly elevated at 1.7 ng/mL. A D-dimer was ordered because of her history of unprovoked DVT/PE, and i...
Source: The Case Files - November 27, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research

The Oversimplification of Cholesterol Testing Can Be Deadly
Early every year, countless Americans embark on a new fitness regime. They go for a physical and maybe for a blood test to measure cholesterol levels. After a clean bill of health, they might train to run a 10K, a marathon or even an Iron man. But what if those tests do not provide a complete picture of your health? What if you are on the verge of a heart attack and have no idea? Before 30, when the human body is at its peak, it can take the strain of being pushed to the limit. As we age, however, cellular changes and the expression of genetic predispositions can dramatically alter our health. Conventional medical tests a...
Source: Healthy Living - The Huffington Post - April 6, 2016 Category: Consumer Health News Source Type: news