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Effect of aqueous olanexidine versus alcohol-based chlorhexidine for surgical skin antisepsis on incidence of surgical site infections in gastrointestinal surgery: multicentre randomised controlled clinical trial (OEDO trial) protocol
Introduction Surgical site infections (SSIs) are among the most common nosocomial infections in surgery patients. Two types of preparations, povidone-iodine and chlorhexidine-alcohol, are commonly used in preoperative antiseptic procedures worldwide. However, there are inconsistencies among international guideline recommendations concerning skin antiseptics. This trial aimed to evaluate the superiority of olanexidine, which reduced SSI rates more than povidone-iodine in our previous randomised trial, over chlorhexidine-alcohol in clean-contaminated surgery. Methods and analysis This multicentre randomised controlled clini...
Source: BMJ Open - August 21, 2023 Category: General Medicine Authors: Takeuchi, M., Obara, H., Furube, T., Kawakubo, H., Kitago, M., Okabayashi, K., Aoyama, J., Amemiya, R., Fujisaki, H., Sano, J., Goto, R., Sato, Y., Kitagawa, Y. Tags: Open access, Surgery Source Type: research

Individual and Sociodemographic Factors Associated with Polysensitization at a New York City Hospital
Allergic contact dermatitis (ACD) is a cutaneous delayed-type hypersensitivity response with a global prevalence estimated at over 20%.1 The gold standard for diagnosis is patch testing, in which allergens are applied to a patient's skin to elicit cutaneous responses in sensitized individuals. Many patients undergoing patch testing test positive for 3 or more unrelated allergens, termed polysensitization.2 A recent North American Contact Dermatitis Group study found that 32.1% of patients tested were positive to at least three allergens, but reported rates vary.
Source: Annals of Allergy, Asthma and Immunology - June 14, 2023 Category: Allergy & Immunology Authors: Sabrina Ghalili, Margaret Downes, Ross O'Hagan, Shayan Owji, Eden David, Stella A Caldas, Grace Rabinowitz, Hannah Verma, Emma Guttman-Yassky, Benjamin Ungar Tags: Letters Source Type: research

Allergies from At-Home Gel and Acrylic Manicures Are On the Rise
Hardly anyone uses normal nail polish anymore, it seems. Now, gel and acrylic manicures are the thing—and you don’t even have to go to a salon to get them. Gel and acrylic manis appeal to many because they can last for three weeks (or even longer) without chipping. In the last few years, the UV lamps required to harden or “cure” more chip-proof polishes have gone from specialty salon tools to household appliances, spurred initially by women seeking salon-style nails during lockdown. There’s a booming market for chemically-hardening products like powders, gels, and putties, often promoted by h...
Source: TIME: Health - May 18, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized healthscienceclimate Public Health Source Type: news

Occupational Chronic Hand Dermatitis in Hospital Environment Successfully Treated with Dupilumab: A Case Report
Iran J Allergy Asthma Immunol. 2022 Aug 12;21(4):484-487. doi: 10.18502/ijaai.v21i4.10296.ABSTRACTDuplilumab is approved to treat mild to moderate atopic dermatitis. It is unclear, however, whether Dupilumab is effective for occupational hand eczema. In this article, we describe a 29-year-old nurse who developed severe hand eczema after working in a hospital for 6 years and received inadequate relief from routine treatment. Duplilumab was administered to the patient with great results.PMID:36243937 | DOI:10.18502/ijaai.v21i4.10296
Source: Iranian Journal of Allergy, Asthma and Immunology - October 16, 2022 Category: Allergy & Immunology Authors: Hui Gan Ya-Dong Gao Source Type: research

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