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Association between depression risk and polycystic ovarian syndrome in young women: a retrospective nationwide population-based cohort study (1998 –2013)
This study was supported in part by the Taiwan Ministry of Health and Welfare Clinical Trial Center (MOHW108-TDU-B-212-133  004), China Medical University Hospital, Academia Sinica Stroke Biosignature Project (BM10701010021), MOST Clinical Trial Consortium for Stroke (MOST 107-2321-B-039 -004-), Tseng-Lien Lin Foundation, Taichung, Taiwan and Katsuzo and Kiyo Aoshima Memorial Funds, Japan. No competing interest existe d.TRIAL REGISTRATION NUMBERN/A.
Source: Human Reproduction - August 13, 2019 Category: Reproduction Medicine Source Type: research

Common diseases as determinants of menopausal age
STUDY QUESTION Can the diagnosis of common diseases before menopause influence age at natural menopause (ANM) onset? SUMMARY ANSWER Polycystic ovary syndrome (PCOS) and depression were observed to delay menopause. WHAT IS KNOWN ALREADY It has been observed that women who undergo early menopause experience a higher burden of health problems related to metabolic syndromes, heart disease and depression, but whether ANM can be influenced by common adult diseases has not been studied extensively. STUDY DESIGN, SIZE, DURATION All women attending mammography screening or clinical mammography at four hospitals in Sweden were in...
Source: Human Reproduction - November 16, 2016 Category: Reproduction Medicine Authors: Li, J., Eriksson, M., Czene, K., Hall, P., Rodriguez-Wallberg, K. A. Tags: Reproductive Epidemiology Source Type: research

Metabolic features of adult and adolescent first-degree relatives of women with polycystic ovary syndrome: a systematic review and meta-analysis
Women with polycystic ovary syndrome (PCOS) have a 2-fold increased risk of metabolic syndrome (1). The risk of metabolic complications in first-degree relatives (FDR) of PCOS women is unclear (2, 3). The present analysis aimed to determine the metabolic risks of adult and adolescent FDR of PCOS women (i.e. fathers, mothers, brothers, sisters, sons and daughters) vs controls. Primary outcomes were mean differences in BMI, and odds for type 2 diabetes mellitus (DM2), metabolic syndrome (MetS), stroke, and myocardial infarction (MI).
Source: Fertility and Sterility - September 1, 2017 Category: Reproduction Medicine Authors: J. Chae, D. Lizneva, A. Sinitsyna, T. Trofimova, L.E. Blake, L.V. Suturina, L. Gavrilova-Jordan, R. Azziz, M.P. Diamond Tags: Poster session Source Type: research

Using the electronic medical record (EMR) for identifying women with polycystic ovary syndrome (PCOS)
PCOS is a common, complex disease, with severe long term sequelae such as anovulatory infertility, endometrial carcinoma, heart attack and stroke. Despite its public healthy importance, PCOS is inconsistently diagnosed due to both its clinical heterogeneity and the use of multiple diagnostic definitions. An innovative approach to identify PCOS cases is to repurpose data routinely collected into the EMR, using the standardized International Classification of Diseases, Ninth and Tenth Revision (ICD-9 and ICD-10) coding system.
Source: Fertility and Sterility - September 1, 2018 Category: Reproduction Medicine Authors: V. Conoscenti, A.N. Kho, G. Hayes Tags: Poster session Source Type: research

Polycystic ovary syndrome: a reproductive and metabolic web of risk, comorbidities, and disease
Polycystic ovary syndrome (PCOS) has been described as the most common endocrine disorder affecting reproductive age women. PCOS is often associated with metabolic dysfunction, obesity, glucose intolerance with hyperinsulinemia, lipid abnormalities. and hypertension. Women with PCOS also suffer higher rates of cardiovascular (CV) disease, peripheral vascular disease, stroke, diabetes, sleep apnea, non-alcoholic fatty liver disease, and breast and uterine cancer. However, rather than a strict cause and effect relationship, many have argued that these conditions are independent or related to a specific feature such as obesit...
Source: Fertility and Sterility - March 1, 2019 Category: Reproduction Medicine Authors: G. Wright Bates Tags: Reflections Source Type: research

Polycystic ovary syndrome: a “risk-enhancing” factor for cardiovascular disease
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic ovarian morphology. Polycystic ovary syndrome, particularly the hyperandrogenism phenotype, is associated with several cardiometabolic abnormalities, including obesity, dyslipidemia, elevated blood pressure, and prediabetes or type 2 diabetes. Many, but not all, studies have suggested that PCOS is associated with increased risk of cardiovascular disease (CVD), including coronary heart disease and stroke, independent of body mass index and traditional risk factors.
Source: Fertility and Sterility - May 1, 2022 Category: Reproduction Medicine Authors: Carolyn Guan, Salman Zahid, Anum S. Minhas, Pamela Ouyang, Arthur Vaught, Valerie L. Baker, Erin D. Michos Tags: Views and reviews Source Type: research