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Total 677 results found since Jan 2013.

Prescription analgesic medication use among osteoarthritis patients
CONCLUSION: The use of gabapentinoid increased rapidly from recent decade, while opioids use did not decrease. The long-term excessive use of opioids was also a serious problem for OA pain control. More improvements such as focusing more on healthcare education and paying more attention on non-pharmacotherapy and the psychological situation of patients are needed.PMID:37724650 | DOI:10.1177/10225536231202835
Source: Journal of Orthopaedic Surgery - September 19, 2023 Category: Orthopaedics Authors: Zhenzhen Huang Xinxin Chen Xihong Gan Jiajia Chen Source Type: research

Naldemedine-induced opioid withdrawal with restlessness as the predominant symptom in a palliative care setting
We report a terminally ill cancer patient who was diagnosed with opioid withdrawal syndrome (OWS) based on symptoms centered around restlessness and sweating that developed 43 days after administration of naldemedine for OIC.RESULTS: The patient was a 78-year-old woman who was diagnosed with stage IVB uterine sarcoma in October, 1 year prior to her visit to our clinic, and underwent chemotherapy after surgery, but the disease became progressive. Thereafter, metastasis to the fourth thoracic vertebrae (Th4) was identified, and loxoprofen and acetaminophen were started for pain at the metastatic site. Oxycodone hydrochloride...
Source: Palliative and Supportive Care - June 23, 2023 Category: Palliative Care Authors: Ryota Sato Mayumi Ishida Nozomu Uchida Takehiko Sakimoto Takefumi Yamaguchi Yoshitaka Ooya Takao Takahashi Hideki Onishi Source Type: research

Early treatment with N-acetylcysteine reduces hepatotoxicity in acute acetaminophen poisoning
We reported a case of a 15-year- old girl referred to our Emergency Department 3 hours after ingestion of 10 g of paracetamol for suicidal purposes. She promptly started the administration of intravenous N-acetylcysteine (NAC) and the patient was discharged after 5 days of hospitalization in good clinical condition and with neuropsychiatric follow-up. Our case shows that the timing of the intravenous NAC administration is considered the most important factor in the prevention of acetaminophen-induced hepatic failure, despite high serum levels after acetaminophen ingestion.PMID:37247196 | DOI:10.23750/abm.v94iS1.13714
Source: Acta Bio-Medica : Atenei Parmensis - May 29, 2023 Category: General Medicine Authors: Serena Ferretti Antonietta Curatola Antonio Chiaretti Benedetta Graglia Antonio Gatto Lavinia Capossela Valeria Pansini Source Type: research

Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10-19 Years During the COVID-19 Pandemic - United States, 2020-2022
MMWR Morb Mortal Wkly Rep. 2023 Apr 21;72(16):426-430. doi: 10.15585/mmwr.mm7216a3.ABSTRACTThe World Health Organization declared COVID-19 a global pandemic on March 11, 2020 (1). As strategies to mitigate the pandemic were implemented, concerns were raised that the containment efforts through quarantine and social distancing practices were negatively affecting the mental and physical health of children and adolescents (2). Suicide is a growing public health problem in the United States. In 2020, suicide was the second leading cause of death among persons aged 10-14 years and the third leading cause among those aged 15-24 ...
Source: MMWR Morb Mortal Wkl... - April 21, 2023 Category: Epidemiology Authors: Rita Farah Saumitra V Rege Ryan J Cole Christopher P Holstege Source Type: research