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Inflammatory bowel disease and cardiovascular diseases
Inflammatory Bowel Disease is comprised of two major subtypes: Crohn's disease and ulcerative colitis, characterized by chronic inflammation of the gastrointestinal tract with extraintestinal manifestations that can involve a number of systems.1 There were estimated to be 7 million cases of inflammatory bowel disease globally in 2017, and at the national level, the United States had the highest age-standardized prevalence rate (464.5 per 100,000 population) of inflammatory bowel disease.2 Atherosclerotic cardiovascular diseases is defined as a history of acute coronary syndrome, myocardial infarction, stable or unstable an...
Source: The American Journal of Medicine - September 1, 2022 Category: General Medicine Authors: Bing Chen, Lauren V Collen, Craig Mowat, Kim L. Isaacs, Siddharth Singh, Sunanda V. Kane, Edward V. Loftus, Francis A. Farraye, Scott Snapper, Hani Jneid, Carl J Lavie, Chayakrit Krittanawong Tags: Clinical Research Study Source Type: research

Combined use of high doses of vasopressin and corticosteroids in a patient with Crohn ’s disease with refractory septic shock after intestinal perforation: a case report
ConclusionsThe significant increase in her cardiac index and stroke volume index resulted in an improvement in peripheral resistance, gas exchange, and urine output and a decrease in her heart rate, interleukin-6 level, and tumor necrosis factor- α level. The administration of high doses of vasopressin and corticosteroids was demonstrated to be safe for the immune system, to reduce the systemic inflammatory response, and to have direct cardiovascular effects. Further studies are required to examine the use of vasopressin as an initial vasop ressor as well as its use in high dosages and in combination with corticosteroids.
Source: Journal of Medical Case Reports - November 13, 2017 Category: General Medicine Source Type: research